Patents by Inventor David R. Colman

David R. Colman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALTERED N-CADHERIN PROCESSING IN TUMOR CELLS BY FURIN AND PROPROTEIN CONVERTASE 5A (PC5A)
    Publication number: 20100310451
    Abstract: The present invention relates to a method for diagnosis and/or prognosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a subject by determining the molecular form of cadherin at the cell surface of cancer cells in the subject. The invention also relates to a method for preventing, inhibiting or treating cancer or its metastasis in a subject by increasing the adhesive forms of cadherin and/or decreasing the non-adhesive forms of cadherin at the cell surface. The invention also relates to a method step of determining the expression level of furin and proprotein convertase 5A (PC5A).
    Type: Application
    Filed: November 3, 2008
    Publication date: December 9, 2010
    Applicants: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARN, IRCM (INSTITUT DE RECHERCHES CLINQUES DE MONTRÉAL), MOUNT SINAI SCHOOL OF MEDICINE
    Inventors: Deborah Maret, David R. Colman, Eugenia Gruzglin, Nabil Seidah
  • Protective peptide antigen
    Patent number: 5614194
    Abstract: Described is a antigen and antigenic amino acid sequence consisting of repeating units of the immunodominant epitope region of the circumsporozoite surface protein of a parasite of the genus Plasmodium. Also described is a related fusion protein produced by a recombinant microorganism and a vaccine for immunizing mammals against malaria.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: March 25, 1997
    Assignee: New York University
    Inventors: David R. Colman, Joan Ellis, G. Nigel Godson, Ruth S. Nussenzweig, Victor N. Nussenzweig, Pamela S. Svec, Fidel Zavala