Abstract: A differential hoist fixture is adapted to secure to the flange of a differential case to provide for the lifting thereof, as in rear axle differentials used in large over the road trucks, mining equipment, and other large industrial wheeled vehicles. The fixture includes two parallel jaws, with one including a clamping bolt therethrough, and a lifting arm at right angles to the two jaws. The clamping bolt may be inwardly angled in the jaw opening, so that as the differential is lifted, the tendency for the flange to slip from the jaw opening will tend to cock the clamping bolt outward, thus applying further clamping force. The opposite jaw may include inwardly angled teeth on the inner surface, facing the clamping bolt, for greater security. The attachment to the lifting arm may be adjustable, by a plurality of bolt holes or an elongated slot for the lifting bolt.