Abstract: One embodiment provides for a media playback device comprising a memory device to store instructions; one or more processors to execute the instructions stored on the memory device, the instructions to cause the one or more processors to provide a playback queue manager to manage one or more media playback queues including a set of media items associated with a scheduled event and a playback routing manager to determine an output destination for the set of media items based on context associated with the scheduled event, the playback routing manager to route output of playback of the set of media items to one or more of multiple different connected media playback devices based on the context associated with the scheduled event.

Abstract: The invention provides methods for treating or preventing cardiac and neurological disorders using chemokine receptor antagonists.

Abstract: A bicycle wheel axle dropout member includes a body portion adapted to be joined to a wheel axle-supporting member of a bicycle and a pair of arm portions extending from the body portion and defining a slot adapted to receive a portion of the bicycle wheel axle in seated relation at the base of the slot. At least one arm portion of the dropout member has a distal part projecting outwardly with respect to the perimeter of the fastener, a hole in the distal part closely adjacent the perimeter of the fastener, and a stop member detachably received in the hole and having a stop head portion positioned abreast of the fastener such as to be engaged by the fastener if the wheel axle should unseat from the base of the slot and to thereby stop the wheel from detaching from the dropout member.

Abstract: A rear carrier rack for a bicycle comprises spaced-apart side members, each of which includes a horizontal portion and an L-shaped portion, an inverted U-bar, an inverted V-bar and a plurality of cross pieces, of which one between the two horizontal portions of the side members supports a pair of adjustable connecting bars and a locking mechanism for such bars. The free ends of the two bars and the two points where the free ends of the V-shaped and U-shaped bars meet serve as the four attachment points of the rack to the bicycle.

Abstract: A racing bicycle frameset comprises a single straight seat tube, the centerline of which intersects the horizontal plane that includes the bottom bracket tube a substantial distance forwardly of the centerline of the bottom bracket tube.

Abstract: Bicycle frame seat stays provide relatively greater lateral stiffness and relatively less vertical stiffness if they are oval-shaped in cross section and oriented with the major axis horizontal.