Patents by Inventor David R. Holmes, III

David R. Holmes, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230283621
    Abstract: In accordance with some embodiments of the disclosed subject matter, mechanisms for distributed network monitoring are provided.
    Type: Application
    Filed: August 6, 2021
    Publication date: September 7, 2023
    Inventors: Robert W. Techentin, David R. Holmes, III, Barry K. Gilbert
  • Patent number: 11229403
    Abstract: Systems and methods are provided for evaluating physiological signal quality. A physiological signal, based on a series measurements on a subject, may be received. A quality of the physiological signal received may be evaluated, and an analysis of the physiological signal may be based at least in part on the quality evaluation.
    Type: Grant
    Filed: January 16, 2018
    Date of Patent: January 25, 2022
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Lukas Smital, David R. Holmes, III, Clifton R. Haider, Barry K. Gilbert
  • Publication number: 20210145346
    Abstract: In accordance with some embodiments of the disclosed subject matter, mechanisms for efficient real-time embedded processing of physiological signals using S transforms are provided. In some embodiments, a system comprises: a sensor configured to monitor at least one condition of the subject and generate physiological feedback data; a processor configured to receive the physiological feedback data from the sensor and programmed to: implement a ECG Leads filter bank with a predetermined number of coefficients and taps selected to perform a Stockwell transform on the physiological feedback data and provide a frequency domain data of the physiological feedback data; analyze the frequency domain data using a physiological monitoring criteria; generate a report about the physiological condition of the subject based on the analysis of the frequency domain data using the physiological monitoring criteria; a display configured to display the report about the physiological condition of the subject.
    Type: Application
    Filed: July 11, 2018
    Publication date: May 20, 2021
    Inventors: David R. Holmes, III, Clifton R. Haider, Lukas Smital, Samuel Cerqueira Pinto, Christopher L. Felton
  • Publication number: 20210022620
    Abstract: In accordance with some embodiments, systems, methods, and media for estimating compensatory reserve and predicting hemodynamic decompensation using physiological data are provided. In some embodiments, a system for estimating compensatory reserve is provided, the system comprising: a processor programmed to: receive a blood pressure waveform of a subject; generate a first sample of the blood pressure waveform with a first duration; provide the sample as input to a trained CNN that was trained using samples of the first duration from blood pressure waveforms recorded from subjects while decreasing the subject's central blood volume, each sample being associated with a compensatory reserve metric; receive, from the trained CNN, a first compensatory reserve metric based on the first sample; and cause information indicative of remaining compensatory reserve to be presented.
    Type: Application
    Filed: July 21, 2020
    Publication date: January 28, 2021
    Inventors: Robert W. Techentin, Timothy B. Curry, Michael J. Joyner, David R. Holmes, III, Clifton R. Haider, Christopher L. Felton, Barry K. Gilbert, Charlotte Sue Van Dorn, William A. Carey
  • Publication number: 20200037961
    Abstract: Systems and methods are provided for evaluating physiological signal quality. A physiological signal, based on a series measurements on a subject, may be received. A quality of the physiological signal received may be evaluated, and an analysis of the physiological signal may be based at least in part on the quality evaluation.
    Type: Application
    Filed: January 16, 2018
    Publication date: February 6, 2020
    Inventors: Lukas Smital, David R. Holmes, III, Clifton R. Haider, Barry K. Gilbert
  • Patent number: 8544474
    Abstract: Systems and methods that provide magnetically-enhanced delivery of therapeutic agents to selected tissue are disclosed. The systems and methods involve the use of carrier devices and release devices and two different magnetic fields to move magnetic particles into selected tissue. Movement of the magnetic particles (and any associated therapeutic agent) into the tissue may be assisted by both magnetic attractive forces as well as magnetic repulsive forces.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: October 1, 2013
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Gurpreet S. Sandhu, David R. Holmes, Jr., Robert D. Simari, Nicole P. Sandhu, David R. Holmes, III
  • Publication number: 20110257460
    Abstract: This document relates to molecularly imprinted polymers for use in mammals. For example, methods and materials for capturing a molecule in the body of a mammal using a molecularly imprinted polymer are provided. In some cases methods for delivering a molecule using a molecularly imprinted polymer into the body of a mammal are provided. The methods provided can be used to target any molecule in the body of a mammal.
    Type: Application
    Filed: November 13, 2009
    Publication date: October 20, 2011
    Inventors: David R. Holmes, Gurpreet S. Sandhu, Robert D. Simari, Nicole P. Sandhu, David R. Holmes, III, Jonathan Harburn
  • Publication number: 20110251454
    Abstract: A system for tracking and evaluating a colonoscopy procedure performed using an endoscope includes a tracking subsystem, a processing subsystem and a display subsystem. The tracking subsystem provides information representative of the location of the endoscope within a patient's colon during the procedure. The processing subsystem generates visualization metrics from images produced by the endoscope during the procedure. The display subsystem is coupled to the tracking and processing subsystems to generate a visual display of the patient's colon with information representative of the visualization metrics at associated colon locations.
    Type: Application
    Filed: November 23, 2009
    Publication date: October 13, 2011
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Richard A. Robb, Gianrico Farrugia, William J. Sandborn, David R. Holmes, III
  • Publication number: 20110178539
    Abstract: This document provides methods and materials related to minimally invasive techniques for reducing the volume of and/or occluding left atrial appendages.
    Type: Application
    Filed: July 8, 2009
    Publication date: July 21, 2011
    Inventors: David R. Holmes, Jr., David R. Holmes, III, Paul A. Friedman, Charles J. Bruce, Samuel J. Asirvatham, Susan B. Johnson, Rebecca B. Fountain
  • Patent number: 7830948
    Abstract: A system provides for remote monitoring using asynchronous code division multiple access (CDMA) communication techniques between a base station and one or more transponders. Each transponder is attached or otherwise associated with an object or an environment to be monitored. Upon receipt of an interrogation signal, a transponder generates and transmits a coded transponder signal containing the monitored data. The coded transponder signal is generated using a spreading code. Each transponder is associated with a unique, mutually exclusive set of spreading codes. Each spreading code is based on a unique transponder address and the monitored data to be sent. A detector asynchronously monitors received signals for any of the available spreading codes. Once the detector detects a particular spreading code, the base station can identify the source transponder and extract the monitored data.
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: November 9, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Timothy Michael Schaefer, Jonathan Darrel Coker, Rick Allen Philpott, Edward Brian Welch, David R. Holmes, III
  • Publication number: 20100121188
    Abstract: This document provides methods and materials that can be used to reduce or prevent contrast agent-induced toxicity. For example, devices for capturing contrast agents from blood are provided.
    Type: Application
    Filed: October 10, 2007
    Publication date: May 13, 2010
    Inventors: Gurpreet S. Sandhu, David R. Holmes, III, David R. Holmes, JR., Nicole P. Sandhu, Robert D. Simari
  • Publication number: 20100066506
    Abstract: A system provides for remote monitoring using asynchronous code division multiple access (CDMA) communication techniques between a base station and one or more transponders. Each transponder is attached or otherwise associated with an object or an environment to be monitored. Upon receipt of an interrogation signal, a transponder generates and transmits a coded transponder signal containing the monitored data. The coded transponder signal is generated using a spreading code. Each transponder is associated with a unique, mutually exclusive set of spreading codes. Each spreading code is based on a unique transponder address and the monitored data to be sent. A detector asynchronously monitors received signals for any of the available spreading codes. Once the detector detects a particular spreading code, the base station can identify the source transponder and extract the monitored data.
    Type: Application
    Filed: November 20, 2009
    Publication date: March 18, 2010
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Timothy Michael Schaefer, Jonathan Darrel Coker, Rick Allen Philpott, Edward Brian Welch, David R. Holmes, III
  • Patent number: 7643536
    Abstract: A system provides for remote monitoring using asynchronous code division multiple access (CDMA) communication techniques between a base station and one or more transponders. Each transponder is attached or otherwise associated with an object or an environment to be monitored. Upon receipt of an interrogation signal, a transponder generates and transmits a coded transponder signal containing the monitored data. The coded transponder signal is generated using a spreading code. Each transponder is associated with a unique, mutually exclusive set of spreading codes. Each spreading code is based on a unique transponder address and the monitored data to be sent. A detector asynchronously monitors received signals for any of the available spreading codes. Once the detector detects a particular spreading code, the base station can identify the source transponder and extract the monitored data.
    Type: Grant
    Filed: August 10, 2004
    Date of Patent: January 5, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Timothy Michael Schaefer, Jonathan Darrel Coker, Rick Allen Philpott, Edward Brian Welch, David R. Holmes, III