Patents by Inventor David R. Kaplan

David R. Kaplan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRK tyrosine kinase receptor is the physiological receptor for nerve growth factor
    Patent number: 5811396
    Abstract: The present invention relates to a complex comprising nerve growth factor (NGF) and trk-proto-oncogene protein. The present invention also relates to methods for detecting the presence of NGF and trk-proto-oncogene receptor. The present invention further relates to methods that can be used in diagnostics and therapeutics for neurodegenerative diseases such as Alzheimer's and Huntington's by detecting NGF-trk receptor pairs and the phosphorylation of trk protein.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 22, 1998
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: David R. Kaplan, Luis F. Parada
  • CDS derivatives and methods of use for cellular modulation and enhancement of cellular engraftment
    Patent number: 5623056
    Abstract: Specific and nonspecific immunomodulation, enhancement of cellular engraftment, and modulation of nonimmune cells are achieved by using various membrane-binding and soluble CD8 compositions.
    Type: Grant
    Filed: December 28, 1993
    Date of Patent: April 22, 1997
    Assignee: TKB Associates Limited Partnership
    Inventors: Mark L. Tykocinski, David R. Kaplan
  • CD8 derivatives and methods of use for cellular modulation and enhancement of cellular engraftment
    Patent number: 5601828
    Abstract: Specific and nonspecific immunomodulation, enhancement of cellular engraftment, and modulation of nonimmune cells are achieved by using various membrane-binding and soluble CD8 compositions.
    Type: Grant
    Filed: August 24, 1993
    Date of Patent: February 11, 1997
    Assignee: TKB Associates Limited Partnership
    Inventors: Mark L. Tykocinski, David R. Kaplan
  • Focal plane array test facility
    Patent number: 5471055
    Abstract: A test system for completely characterizing all known types of infrared and ar-infrared detector arrays for FLIR imagers, which utilizes a number of different radiation sources, array supports, radiation filters, and radiation stops all remotely controlled and positioned by a computer which performs the test, sorts the data collected the results and presents it in a variety of formats. Also an automatic test method for characterizing infrared detectors using remote controlled radiation sources and dewar mounting devices under computer control.
    Type: Grant
    Filed: May 28, 1993
    Date of Patent: November 28, 1995
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Christopher R. Costanzo, David R. Kaplan, Khoa V. Dang
  • Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells
    Patent number: 5242687
    Abstract: Specific and nonspecific immunomodulation, enhancement of cellular engraftment, and modulation of nonimmune cells are achieved by using various membrane-binding and soluble CD8 compositions.
    Type: Grant
    Filed: April 25, 1991
    Date of Patent: September 7, 1993
    Assignee: TKB Associates Limited Partnership
    Inventors: Mark L. Tykocinski, David R. Kaplan
  • Flexible membrane circuit tester
    Patent number: 5079501
    Abstract: A pattern of electrodes, with electrical lead lines to the electrodes, are arried by a thin-film membrane mounted on a frame. The pattern corresponds to a test point pattern on a circuit to be tested. The lead lines go to edge connectors on the frame. In order to test a circuit, the membrane is pushed against the test points by air pressure, such that capacitive coupling occurs between the electrodes and the test points.
    Type: Grant
    Filed: February 22, 1991
    Date of Patent: January 7, 1992
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Brian S. Miller, David R. Kaplan
  • Flexible membrane circuit tester
    Patent number: 5072176
    Abstract: A pattern of electrodes, with electrical lead lines to the electrodes, are arried by a thin-film membrane mounted on a frame. The pattern corresponds to a test point pattern on a circuit to be tested. The lead lines go to edge connectors on the frame. In order to test a circuit, the membrane is pushed against the test points by air pressure, such that capacitive coupling occurs between the electrodes and the test points.
    Type: Grant
    Filed: February 22, 1991
    Date of Patent: December 10, 1991
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Brian S. Miller, David R. Kaplan
  • Method of making a flexible membrane circuit tester
    Patent number: 5062203
    Abstract: A pattern of electrodes, with electrical lead lines to the electrodes, are arried by a thin-film membrane mounted on a frame. The pattern corresponds to a test point pattern on a circuit to be tested. The lead lines go to edge connectors on the frame. In order to test a circuit, the membrane is pushed against the test points by air pressure, such that capacitive coupling occurs between the electrodes and the test points.
    Type: Grant
    Filed: February 22, 1991
    Date of Patent: November 5, 1991
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Brian S. Miller, David R. Kaplan
  • Method of making a flexible membrane circuit tester
    Patent number: 5062204
    Abstract: A pattern of electrodes, with electrical lead lines to the electrodes, are arried by a thin-film membrane mounted on a frame. The pattern corresponds to a test point pattern on a circuit to be tested. The lead lines go to edge connectors on the frame. In order to test a circuit, the membrane is pushed against the test points by air pressure, such that capacitive coupling occurs between the electrodes and the test points.
    Type: Grant
    Filed: February 22, 1991
    Date of Patent: November 5, 1991
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Brian S. Miller, David R. Kaplan
  • Flexible membrane circuit tester
    Patent number: 5055776
    Abstract: A pattern of electrodes, with electrical lead lines to the electrodes, are arried by a thin-film membrane mounted on a frame. The pattern corresponds to a test point pattern on a circuit to be tested. The lead lines go to edge connectors on the frame. In order to test a circuit, the membrane is pushed against the test points by air pressure, such that capacitive coupling occurs between the electrodes and the test points.
    Type: Grant
    Filed: July 10, 1990
    Date of Patent: October 8, 1991
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Brian S. Miller, David R. Kaplan
  • Method of making a flexible membrane circuit tester
    Patent number: 5046239
    Abstract: A pattern of electrodes, with electrical lead lines to the electrodes, are arried by a thin-film membrane mounted on a frame. The pattern corresponds to a test point pattern on a circuit to be tested. The lead lines go to edge connectors on the frame. In order to test a circuit, the membrane is pushed against the test points by air pressure, such that capacitive coupling occurs between the electrodes and the test points.
    Type: Grant
    Filed: February 22, 1991
    Date of Patent: September 10, 1991
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Brian S. Miller, David R. Kaplan