Patents by Inventor David R. Latulippe

David R. Latulippe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multiplexed microcolumn devices and processes for selection of nucleic acid aptamers
    Patent number: 10132798
    Abstract: The present invention relates to a microcolumn device for selecting nucleic acid aptamers for single and multiple target molecules, as well as a method for making the microcolumn device. The present invention also relates to a system for selecting nucleic acid aptamers for single and multiple target molecules. The present invention further relates to methods of using the microcolumn device for selecting nucleic acid aptamers for multiple target molecules. Kits that include one or more microcolumn device and/or system of the present invention are also disclosed.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: November 20, 2018
    Assignee: CORNELL UNIVERSITY
    Inventors: Harold G. Craighead, David R. Latulippe, John T. Lis, Abdullah Ozer, Kylan Szeto
  • RNA APTAMER ISOLATION VIA DUAL-CYCLE (RAPID) SELECTION
    Publication number: 20150291952
    Abstract: The present invention relates to a method for selecting an aptamer for a target molecule. The method involves providing a random oligonucleotide library comprising a plurality of unique random sequence oligonucleotides; providing a target mixture comprising at least one target molecule; and subjecting the random oligonucleotide library and the target mixture to at least one round of an aptamer isolation protocol to yield at least one aptamer for the target molecule, wherein a round of the aptamer isolation protocol comprises at least one selection cycle followed by an amplification cycle. The present invention also relates to systems and devices for implementing or performing the method of the present invention. The present invention further relates to using the method to isolate aptamers for high-throughput sequencing analysis and other aptamer analysis protocols.
    Type: Application
    Filed: August 15, 2013
    Publication date: October 15, 2015
    Applicant: CORNELL UNIVERSITY
    Inventors: Harold G. Craighead, David R. Latulippe, John T. Lis, Abdullah Ozer, Kylan Szeto
  • MULTIPLEXED MICROCOLUMN DEVICES AND PROCESSES FOR SELECTION OF NUCLEIC ACID APTAMERS
    Publication number: 20150204859
    Abstract: The present invention relates to a microcolumn device for selecting nucleic acid aptamers for single and multiple target molecules, as well as a method for making the microcolumn device. The present invention also relates to a system for selecting nucleic acid aptamers for single and multiple target molecules. The present invention further relates to methods of using the microcolumn device for selecting nucleic acid aptamers for multiple target molecules. Kits that include one or more microcolumn device and/or system of the present invention are also disclosed.
    Type: Application
    Filed: May 13, 2013
    Publication date: July 23, 2015
    Applicant: CORNELL UNIVERSITY
    Inventors: Harold G. Craighead, David R. Latulippe, John T. Lis, Abdullah Ozer, Kylan Szeto