Patents by Inventor David R. Liston

David R. Liston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES
    Publication number: 20170253645
    Abstract: Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.
    Type: Application
    Filed: February 15, 2017
    Publication date: September 7, 2017
    Inventors: Guido Cappuccilli, Roberto Crea, Randy Shen, Craig A. Hokanson, Peter B. Kirk, David R. Liston
  • Universal fibronectin type III binding-domain libraries
    Patent number: 9376483
    Abstract: Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having high binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: June 28, 2016
    Assignee: Protelica, Inc.
    Inventors: Guido Cappuccilli, Roberto Crea, Randy Shen, Craig A. Hokanson, Peter B. Kirk, David R. Liston
  • UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES
    Publication number: 20140206576
    Abstract: Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.
    Type: Application
    Filed: January 8, 2014
    Publication date: July 24, 2014
    Inventors: Guido Cappuccilli, Roberto Crea, Randy Shen, Craig A. Hokanson, Peter B. Kirk, David R. Liston
  • UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES
    Publication number: 20140135474
    Abstract: Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having high binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins.
    Type: Application
    Filed: May 22, 2013
    Publication date: May 15, 2014
    Applicant: PROTELICA, INC.
    Inventors: Guido Cappuccilli, Robert Crea, Randy Shen, Craig A. Hokanson, Peter B. Kirk, David R. Liston
  • Universal fibronectin type III binding-domain libraries
    Patent number: 8697608
    Abstract: Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: April 15, 2014
    Assignee: Protelica, Inc.
    Inventors: Guido Cappuccilli, Roberto Crea, Randy Shen, Craig A. Hokanson, Peter B. Kirk, David R. Liston
  • Universal fibronectin Type III binding-domain libraries
    Patent number: 8680019
    Abstract: Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.
    Type: Grant
    Filed: September 18, 2009
    Date of Patent: March 25, 2014
    Assignee: Protelica, Inc.
    Inventors: Guido Cappuccilli, Roberto Crea, Randy Shen, Craig A. Hokanson, Peter B. Kirk, David R. Liston
  • Universal fibronectin type III binding-domain libraries
    Patent number: 8470966
    Abstract: Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having high binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins.
    Type: Grant
    Filed: June 21, 2010
    Date of Patent: June 25, 2013
    Assignee: Protelica, Inc.
    Inventors: Guido Cappuccilli, Roberto Crea, Randy Shen, Craig A. Hokanson, Peter B. Kirk, David R. Liston
  • UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES
    Publication number: 20110124527
    Abstract: Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.
    Type: Application
    Filed: August 4, 2010
    Publication date: May 26, 2011
    Inventors: Guido Cappuccilli, Roberto Crea, Randy Shen, Craig A. Hokanson, Peter B. Kirk, David R. Liston
  • UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES
    Publication number: 20110021746
    Abstract: Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having hign binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins.
    Type: Application
    Filed: June 21, 2010
    Publication date: January 27, 2011
    Inventors: Guido Cappuccilli, Roberto Crea, Randy Shen, Craig A. Hokanson, Peter B. Kirk, David R. Liston
  • UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES
    Publication number: 20100152063
    Abstract: Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.
    Type: Application
    Filed: September 18, 2009
    Publication date: June 17, 2010
    Applicant: ProtElix, Inc.
    Inventors: Guido Cappuccilli, Roberto Crea, Randy Shen, Craig A. Hokanson, Peter B. Kirk, David R. Liston
  • Universal fibronectin type III binding-domain libraries
    Publication number: 20090176654
    Abstract: Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.
    Type: Application
    Filed: August 11, 2008
    Publication date: July 9, 2009
    Applicant: ProtElix, Inc.
    Inventors: Guido Cappuccilli, Roberto Crea, Randy Shen, Craig A. Hokanson, Peter B. Kirk, David R. Liston