Patents by Inventor David R. Mack

David R. Mack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11933790
    Abstract: A method of isotope-labelling a microbiota sample. It involves providing a first microbiota sample that was obtained from a given source; exposing the first microbiota sample to an isotope enriched medium; and culturing the exposed first microbiota sample in the isotope enriched medium to obtain an isotope-labelled microbiota sample, wherein the isotope labelled metaproteome of the isotope-labelled microbiota sample is taxon specific for taxa present in the first microbiota sample when initially obtained from the given source.
    Type: Grant
    Filed: January 27, 2021
    Date of Patent: March 19, 2024
    Assignee: UNIVERSITY OF OTTAWA
    Inventors: Joseph Michel Daniel Figeys, Alain Christophe Stintzi, David R. Mack, Xu Zhang, Zhibin Ning
  • Patent number: 11175294
    Abstract: A method of isotope-labelling a microbiota sample. It involves providing a first microbiota sample that was obtained from a given source; exposing the first microbiota sample to an isotope enriched medium; and culturing the exposed first microbiota sample in the isotope enriched medium to obtain an isotope-labelled microbiota sample, wherein the isotope labelled metaproteome of the isotope-labelled microbiota sample is taxon specific for taxa present in the first microbiota sample when initially obtained from the given source.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: November 16, 2021
    Assignee: University Of Ottawa
    Inventors: Joseph Michel Daniel Figeys, Alain Christophe Stintzi, David R. Mack, Xu Zhang, Zhibin Ning
  • Patent number: 11104965
    Abstract: There is provided methods and compositions to diagnose, classify and treat inflammatory bowel disease including ulcerative colitis and Crohn's disease by measuring the levels of certain bacterial taxa and proteins collected from the gut.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: August 31, 2021
    Inventors: Alain Stintzi, David R. Mack, Joseph Michel Daniel Figeys, Walid Abdelfattah Elsayed Mottawea, Turki Saleh A. Abujamel, Cheng-kang Chiang
  • Publication number: 20210255197
    Abstract: A method of isotope-labelling a microbiota sample. It involves providing a first microbiota sample that was obtained from a given source; exposing the first microbiota sample to an isotope enriched medium; and culturing the exposed first microbiota sample in the isotope enriched medium to obtain an isotope-labelled microbiota sample, wherein the isotope labelled metaproteome of the isotope-labelled microbiota sample is taxon specific for taxa present in the first microbiota sample when initially obtained from the given source.
    Type: Application
    Filed: January 27, 2021
    Publication date: August 19, 2021
    Inventors: Joseph Michel Daniel FIGEYS, Alain Christophe STINTZI, David R. MACK, Xu ZHANG, Zhibin NING
  • Publication number: 20200191803
    Abstract: A method for determining a presence of inflammatory bowel disease in a subject. The method involves providing a gut sample obtained from a subject; measuring a level in said gut sample of one or more proteins, wherein said one or more proteins comprises at least one of: leukotriene A-4 hydrolase, catalase, transketolase, thioredoxin domain containing protein 17, vasodilator-stimulated phosphoprotein and thymosin beta-10; and comparing said measured level of each of said one or more proteins to a corresponding protein level for a normal subject. A method for determining a presence of pancolitis in a subject with ulcerative colitis is also provided.
    Type: Application
    Filed: June 14, 2018
    Publication date: June 18, 2020
    Inventors: Joseph Michel Daniel FIGEYS, Alain Christophe STINTZI, David R. MACK, Amanda Elizabeth Starr, Shelley A. Deeke
  • Publication number: 20190331693
    Abstract: A method of isotope-labelling a microbiota sample. It involves providing a first microbiota sample that was obtained from a given source; exposing the first microbiota sample to an isotope enriched medium; and culturing the exposed first microbiota sample in the isotope enriched medium to obtain an isotope-labelled microbiota sample, wherein the isotope labelled metaproteome of the isotope-labelled microbiota sample is taxon specific for taxa present in the first microbiota sample when initially obtained from the given source.
    Type: Application
    Filed: June 1, 2017
    Publication date: October 31, 2019
    Inventors: Joseph Michel Daniel FIGEYS, Alain Christophe STINTZI, David R. MACK, Xu ZHANG, Zhibin NING
  • Patent number: 10228379
    Abstract: There is provided protein biomarkers and methods for their use in diagnosing and treating Inflammatory Bowel Disease (IBD), ulcerative colitis (UC) and Crohn's disease (CD) as well as methods for assessing the severity of the diseases.
    Type: Grant
    Filed: May 28, 2018
    Date of Patent: March 12, 2019
    Assignee: UNIVERSITY OF OTTAWA
    Inventors: Daniel Figeys, Alain Stintzi, David R. Mack, Cheng-Kang Chiang, Amanda Elizabeth Starr
  • Publication number: 20180320222
    Abstract: There is provided methods and compositions to diagnose, classify and treat inflammatory bowel disease including ulcerative colitis and Crohn's disease by measuring the levels of certain bacterial taxa and proteins collected from the gut.
    Type: Application
    Filed: July 6, 2018
    Publication date: November 8, 2018
    Inventors: Alain STINTZI, David R. MACK, Daniel FIGEYS, Walid Abdelfattah Elsayed Mottawea, Turki Saleh A. ABUJAMEL, Cheng-kang CHIANG
  • Publication number: 20180275142
    Abstract: There is provided protein biomarkers and methods for their use in diagnosing and treating Inflammatory Bowel Disease (IBD), ulcerative colitis (UC) and Crohn's disease (CD) as well as methods for assessing the severity of the diseases.
    Type: Application
    Filed: May 28, 2018
    Publication date: September 27, 2018
    Inventors: Daniel FIGEYS, Alain STINTZI, David R. MACK, Cheng-Kang CHIANG, Amanda Elizabeth STARR
  • Patent number: 10023918
    Abstract: There is provided methods and compositions to diagnose, classify and treat inflammatory bowel disease including ulcerative colitis and Crohn's disease by measuring the levels of certain bacterial taxa and proteins collected from the gut.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: July 17, 2018
    Assignee: UNIVERSITY OF OTTAWA
    Inventors: Alain Stintzi, David R. Mack, Daniel Figeys, Walid Abdelfattah Elsayed Mottawea, Turki Saleh A. Abujamel, Cheng-kang Chiang
  • Patent number: 10001493
    Abstract: There is provided protein biomarkers and methods for their use in diagnosing and treating Inflammatory Bowel Disease (IBD), ulcerative colitis (UC) and Crohn's disease (CD) as well as methods for assessing the severity of the diseases.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: June 19, 2018
    Assignee: UNIVERSITY OF OTTAWA
    Inventors: Daniel Figeys, Alain Stintzi, David R. Mack, Cheng-Kang Chiang, Amanda Elizabeth Starr
  • Publication number: 20170205429
    Abstract: There is provided protein biomarkers and methods for their use in diagnosing and treating Inflammatory Bowel Disease (IBD), ulcerative colitis (UC) and Crohn's disease (CD) as well as methods for assessing the severity of the diseases.
    Type: Application
    Filed: April 3, 2017
    Publication date: July 20, 2017
    Inventors: Daniel FIGEYS, Alain STINTZI, David R. MACK, Cheng-Kang CHIANG, Amanda Elizabeth STARR
  • Publication number: 20160032363
    Abstract: There is provided methods and compositions to diagnose, classify and treat inflammatory bowel disease including ulcerative colitis and Crohn's disease by measuring the levels of certain bacterial taxa and proteins collected from the gut.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: Alain STINTZI, David R. MACK, Daniel FIGEYS, Walid METTAWEA, Turki ABUJAMEL, Cheng-kang CHIANG
  • Publication number: 20110066518
    Abstract: A bid invalidating auction system may include a memory, an interface, and a processor. The memory stores a plurality of elements characterized by an ordering in which the elements will be rendered ineligible to win a contest. The processor provides, via the interface, the elements to the users, and receives, via the interface, a selection of an element from a user. The processor associates the element with the user if the element is eligible and not associated with another user. The processor renders the next eligible element in the ordering ineligible, if the first element is associated with the first user. The processor repeats the receive, associate, identify and render until an occurrence of an event. Upon the occurrence of the event, the processor identifies the next eligible element in the ordering which is associated with a user and designates the associated user the winner.
    Type: Application
    Filed: September 16, 2009
    Publication date: March 17, 2011
    Inventors: David R. Mack, Stephen C. P. Mack
  • Patent number: 7536644
    Abstract: The preferred embodiments described herein provide a method and system for facilitating selection of stored medical images. In one preferred embodiment, a plurality of medical images are stored, and, for each medical image, the settings of at least one acquisition time control used to create the image are also stored. During image review, a user selects a set of acquisition time control settings, and a set of medical images is automatically selected from the stored images based on the selected set of acquisition time control settings. Other preferred embodiments are provided, and each of the preferred embodiments described herein can be used alone or in combination with one another.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: May 19, 2009
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Kenneth M. Fowkes, Laurence S. McCabe, Paul D. Miller, David R. Mack, Ruth E. Leibig
  • Publication number: 20040001080
    Abstract: The preferred embodiments described herein provide a method and system for facilitating selection of stored medical images. In one preferred embodiment, a plurality of medical images are stored, and, for each medical image, the settings of at least one acquisition time control used to create the image are also stored. During image review, a user selects a set of acquisition time control settings, and a set of medical images is automatically selected from the stored images based on the selected set of acquisition time control settings. Other preferred embodiments are provided, and each of the preferred embodiments described herein can be used alone or in combination with one another.
    Type: Application
    Filed: June 27, 2002
    Publication date: January 1, 2004
    Inventors: Kenneth M. Fowkes, Laurence S. McCabe, Paul D. Miller, David R. Mack, Ruth E. Leibig