Patents by Inventor David R. Mott
David R. Mott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10099417Abstract: A sheath flow system having a channel with at least one fluid transporting structure located in the top and bottom surfaces situated so as to transport the sheath fluid laterally across the channel to provide sheath fluid fully surrounding the core solution. At the point of introduction into the channel, the sheath fluid and core solutions flow side by side within the channel or the core solution may be bounded on either side by the sheath fluid. The system is functional over a broad channel size range and with liquids of high or low viscosity. The design can be readily incorporated into microfluidic chips without the need for special manufacturing protocols. Uses include extruding materials and/or fabricating structures.Type: GrantFiled: August 12, 2015Date of Patent: October 16, 2018Assignee: The United States of America, as represented by the Secretary of the NavyInventors: David R. Mott, Frances S. Ligler, Stephanie Fertig, Aron Bobrowski
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Publication number: 20180056586Abstract: A method of direct-write manufacturing (3D printing) includes a simple to manufacture printhead configured to create sheathed flow. The method is operable at room temperature and suitable for use with sensitive materials.Type: ApplicationFiled: August 25, 2017Publication date: March 1, 2018Inventors: David R. Mott, André A. Adams, Jonathan D. Yuen, Michael A. Daniele
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Patent number: 9649803Abstract: A sheath flow system having a channel with at least one fluid transporting structure located in the top and bottom surfaces situated so as to transport the sheath fluid laterally across the channel to provide sheath fluid fully surrounding the core solution. At the point of introduction into the channel, the sheath fluid and core solutions flow side by side within the channel or the core solution may be bounded on either side by the sheath fluid. The system is functional over a broad channel size range and with liquids of high or low viscosity. The design can be readily incorporated into microfluidic chips without the need for special manufacturing protocols. Uses include extruding materials and/or fabricating structures.Type: GrantFiled: May 29, 2015Date of Patent: May 16, 2017Assignee: The United States of America, as represented by the Secretary of the NavyInventors: David R. Mott, Peter B. Howell, Jr., Frances S. Ligler, Stephanie Fertig, Aron Bobrowski
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Patent number: 9573311Abstract: A sheath flow system having a channel with first and second fluid transporting structures located on opposing surfaces facing one another across the channel in the top and bottom surfaces of the channel situated so as to transport the sheath fluid laterally across the channel to provide sheath fluid fully surrounding the core solution. At the point of introduction into the channel, the sheath fluid and core solutions flow side by side within the channel or the core solution may be bounded on either side by the sheath fluid. The system is functional over a broad channel size range and with liquids of high or low viscosity. The design can be readily incorporated into microfluidic chips without the need for special manufacturing protocols.Type: GrantFiled: December 27, 2012Date of Patent: February 21, 2017Assignee: The United States of America, as represented by the Secretary of the NavyInventors: David R. Mott, Peter B. Howell, Jr., Frances S. Ligler, Stephanie Fertig, Aron Bobrowski
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Publication number: 20150343691Abstract: A sheath flow system having a channel with at least one fluid transporting structure located in the top and bottom surfaces situated so as to transport the sheath fluid laterally across the channel to provide sheath fluid fully surrounding the core solution. At the point of introduction into the channel, the sheath fluid and core solutions flow side by side within the channel or the core solution may be bounded on either side by the sheath fluid. The system is functional over a broad channel size range and with liquids of high or low viscosity. The design can be readily incorporated into microfluidic chips without the need for special manufacturing protocols. Uses include extruding materials and/or fabricating structures.Type: ApplicationFiled: August 12, 2015Publication date: December 3, 2015Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: David R. Mott, Peter B. Howell, JR., Frances S. Ligler, Stephanie Fertig, Aron Bobrowski
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Publication number: 20150266226Abstract: A sheath flow system having a channel with at least one fluid transporting structure located in the top and bottom surfaces situated so as to transport the sheath fluid laterally across the channel to provide sheath fluid fully surrounding the core solution. At the point of introduction into the channel, the sheath fluid and core solutions flow side by side within the channel or the core solution may be bounded on either side by the sheath fluid. The system is functional over a broad channel size range and with liquids of high or low viscosity. The design can be readily incorporated into microfluidic chips without the need for special manufacturing protocols. Uses include extruding materials and/or fabricating structures.Type: ApplicationFiled: May 29, 2015Publication date: September 24, 2015Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: David R. Mott, Peter B. Howell, JR., Frances S. Ligler, Stephanie Fertig, Aron Bobrowski
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Publication number: 20140087466Abstract: A fiber includes one or more layers of polymer surrounding a central lumen, and living animal cells disposed within the lumen and/or within at least one of the one or more layers, wherein the fiber has an outer diameter of between 5 and 8000 microns and wherein each individual layer of polymer has a thickness of between 0.1 and 250 microns. Also disclosed are model tissues including such fibers, and method of making such fibers. The fibers can serve as synthetic blood vessels, ducts, or nerves.Type: ApplicationFiled: March 4, 2013Publication date: March 27, 2014Inventors: Frances S. Ligler, André A. Adams, Michael Daniele, David R. Mott, Peter B. Howell, JR., Stephanie Fertig, Aron Bobrowski
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Publication number: 20140017149Abstract: A sheath flow system having a channel with first and second fluid transporting structures located on opposing surfaces facing one another across the channel in the top and bottom surfaces of the channel situated so as to transport the sheath fluid laterally across the channel to provide sheath fluid fully surrounding the core solution. At the point of introduction into the channel, the sheath fluid and core solutions flow side by side within the channel or the core solution may be bounded on either side by the sheath fluid. The system is functional over a broad channel size range and with liquids of high or low viscosity.Type: ApplicationFiled: December 27, 2012Publication date: January 16, 2014Inventors: David R. Mott, Peter B. Howell, JR., Frances S. Ligler, Stephanie Fertig, Aron Bobrowski
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Patent number: 8132443Abstract: The present invention is generally directed to a microfabricated gas chromatograph column having two patterned substrates, each optionally having a stationary phase material coating, bonded together to provide a continuous flow channel. The flow channel can have a serpentine arrangement or a modified serpentine arrangement comprising alternating series of consecutive turns in one direction where each series has enough turns to move carrier gas and analyte molecules from the center of the column cross section to an outer wall of the channel or from one outer wall of the channel to the opposite outer wall. Different portions of the substrates can be coated with differing thicknesses of stationary phase material and/or with different stationary phase materials. The column can have a circular cross-section or a semi-circular cross-section where the flat portion of the cross-section has grooves. Also disclosed is the related method of making the microfabricated gas chromatograph column.Type: GrantFiled: May 1, 2009Date of Patent: March 13, 2012Assignee: The United States of America as represented by the Secretary of the NavyInventors: R Andrew McGill, Rekha Pai, David R. Mott, Jennifer L Stepnowski, Viet Nguyen
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Publication number: 20090272270Abstract: The present invention is generally directed to a microfabricated gas chromatograph column having two patterned substrates, each optionally having a stationary phase material coating, bonded together to provide a continuous flow channel. The flow channel can have a serpentine arrangement or a modified serpentine arrangement comprising alternating series of consecutive turns in one direction where each series has enough turns to move carrier gas and analyte molecules from the center of the column cross section to an outer wall of the channel or from one outer wall of the channel to the opposite outer wall. Different portions of the substrates can be coated with differing thicknesses of stationary phase material and/or with different stationary phase materials. The column can have a circular cross-section or a semi-circular cross-section where the flat portion of the cross-section has grooves. Also disclosed is the related method of making the microfabricated gas chromatograph column.Type: ApplicationFiled: May 1, 2009Publication date: November 5, 2009Inventors: R Andrew McGill, Rekha Pai, David R. Mott, Jennifer L. Stepnowski, Viet Nguyen