Patents by Inventor David R. Shaffer

David R. Shaffer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Upgrading carbonaceous materials
    Patent number: 8778036
    Abstract: Disclosed are methods for upgrading carbonaceous materials. Also disclosed are apparatuses for upgrading carbonaceous materials. Also disclosed are systems for upgrading carbonaceous materials. Also disclosed are upgraded carbonaceous materials.
    Type: Grant
    Filed: August 22, 2011
    Date of Patent: July 15, 2014
    Assignee: Skye Energy Holdings, Inc.
    Inventor: David R. Shaffer
  • Hepatitis A virus deletion mutants and vaccine formulations containing the same
    Patent number: 6136322
    Abstract: Disclosed are live hepatitis A virus deletion mutants having a deletion mutation in the 5' nontranslated region of the viral genome. The deletion mutation may be selected from the group consisting of (a) pY1 deletion mutations that cause the virus to retain the ability to replicate in monkey kidney cells; and (b) deletion mutations between nucleotides 140 and 144 that render the virus temperature sensitive. Advantageously, the deletion mutation may be an attenuating mutation. Pharmaceutical formulations containing such viruses are disclosed, along with the use thereof to produce antibodies useful for diagnostic purposes and for imparting protective immunity against hepatitis A virus.
    Type: Grant
    Filed: June 15, 1998
    Date of Patent: October 24, 2000
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Stanley M. Lemon, David R. Shaffer
  • Hepatitis A virus deletion mutants and vaccine formulations containing the same
    Patent number: 5766906
    Abstract: Disclosed are live hepatitis A virus deletion mutants having a deletion mutation in the 5' nontranslated region of the viral genome. The deletion mutation may be selected from the group consisting of (a) pY1 deletion mutations that cause the virus to retain the ability to replicate in monkey kidney cells; and (b) deletion mutations between nucleotides 140 and 144 that render the virus temperature sensitive. Advantageously, the deletion mutation may be an attenuating mutation. Pharmaceutical formulations containing such viruses are disclosed, along with the use thereof to produce antibodies useful for diagnostic purposes and for imparting protective immunity against hepatitis A virus.
    Type: Grant
    Filed: July 11, 1994
    Date of Patent: June 16, 1998
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Stanley M. Lemon, David R. Shaffer