Patents by Inventor David R Wisely
David R Wisely has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12209443Abstract: Various examples are directed to apparatus and methods for providing a door latch block assembly. An apparatus includes a first planar surface configured to mount parallel to and facing away from a first side of a door frame, and a second planar surface configured to mount flush with and facing toward the first side of the door frame. The apparatus further includes a rectangular protrusion extending from the second planar surface configured to extend through an aperture in the door frame and protrude from a second side of the door frame. The apparatus also includes cylindrical openings extending through the latch block apparatus configured to receive hardware for affixing a latching mechanism to a distal end of the protrusion. The apparatus is configured to provide precise alignment of the latching mechanism for securing the door frame to a door.Type: GrantFiled: May 20, 2022Date of Patent: January 28, 2025Assignee: Activar Construction Products Group, Inc.Inventors: David R. Wise, Kim Thomas Sefton Band, David John Ashcroft
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Publication number: 20220372788Abstract: Various examples are directed to apparatus and methods for providing a door latch block assembly. An apparatus includes a first planar surface configured to mount parallel to and facing away from a first side of a door frame, and a second planar surface configured to mount flush with and facing toward the first side of the door frame. The apparatus further includes a rectangular protrusion extending from the second planar surface configured to extend through an aperture in the door frame and protrude from a second side of the door frame. The apparatus also includes cylindrical openings extending through the latch block apparatus configured to receive hardware for affixing a latching mechanism to a distal end of the protrusion. The apparatus is configured to provide precise alignment of the latching mechanism for securing the door frame to a door.Type: ApplicationFiled: May 20, 2022Publication date: November 24, 2022Inventors: David R. Wise, Kim Thomas Sefton Band, David John Ashcroft
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Patent number: 11262362Abstract: The present invention provides biomarkers for sensitive, specific, accurate and quantitative diagnosis and assessment of chronic hypoxia. In particular, the present invention provides 2-hydroxyglutarate as a biomarker that is differentially produced in chronic hypoxia. Furthermore, embodiments of the invention are able to differentiate between chronic and acute hypoxia. Assays for levels of 2-hydroxyglutarate may be used alone or in conjunction with additional biomarkers of hypoxia to increase the precision of analysis. In particular embodiments of the invention, the level of 2-hydroxyglutarate and at least one second biomarker may be assayed to generate a hypoxic profile that can be compared to a reference or control profile, thereby diagnosing a subject as normoxic, chronically hypoxic, or acutely hypoxic.Type: GrantFiled: November 18, 2012Date of Patent: March 1, 2022Assignee: Memorial Sloan-Kettering Cancer CenterInventors: David R. Wise, Patrick S. Ward, Craig B. Thompson
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Patent number: 9631407Abstract: An access door for insertion into an opening in a construction surface is provided. The access door has a frame for engagement with edges of the opening in the construction surface. The frame has a channel formed therein for receiving a thermally insulative material to provide a thermal break between the frame and the construction surface. A door is operatively coupled to the frame and movable between an open position allowing access through the opening in the construction surface and a closed position preventing access through the opening in the construction surface.Type: GrantFiled: May 21, 2015Date of Patent: April 25, 2017Assignee: Maxam Metal Products LimitedInventors: David R. Wise, Kim Thomas Sefton Band
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Publication number: 20160123068Abstract: An access door for insertion into an opening in a construction surface is provided. The access door has a frame for engagement with edges of the opening in the construction surface. The frame has a channel formed therein for receiving a thermally insulative material to provide a thermal break between the frame and the construction surface. A door is operatively coupled to the frame and movable between an open position allowing access through the opening in the construction surface and a closed position preventing access through the opening in the construction surface.Type: ApplicationFiled: May 21, 2015Publication date: May 5, 2016Inventors: David R. WISE, Kim Thomas Sefton BAND
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Publication number: 20160033533Abstract: The present invention provides biomarkers for sensitive, specific, accurate and quantitative diagnosis and assessment of chronic hypoxia. In particular, the present invention provides 2-hydroxyglutarate as a biomarker that is differentially produced in chronic hypoxia. Furthermore, embodiments of the invention are able to differentiate between chronic and acute hypoxia. Assays for levels of 2-hydroxyglutarate may be used alone or in conjunction with additional biomarkers of hypoxia to increase the precision of analysis. In particular embodiments of the invention, the level of 2-hydroxyglutarate and at least one second biomarker may be assayed to generate a hypoxic profile that can be compared to a reference or control profile, thereby diagnosing a subject as normoxic, chronically hypoxic, or acutely hypoxic.Type: ApplicationFiled: November 28, 2012Publication date: February 4, 2016Inventors: David R. Wise, Patrick S. Ward, Craig B. Thompson
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Publication number: 20160017567Abstract: A clip-in access door for covering an opening in a construction surface has a frame for mounting in the opening, a door mounted on the frame, and a plurality of clips mounted on the frame for securing the frame in the opening of the construction surface. The clips along at least one edge of the frame are rotatable between an insert position and a lock position. Methods of using the clip-in access door are provided.Type: ApplicationFiled: July 15, 2015Publication date: January 21, 2016Inventors: David R. WISE, Kim Thomas Sefton BAND
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Patent number: 8934901Abstract: When a mobile station MS1 determines during communication through a first network (1), that a second network (7) is available that offers better operational parameters for the communication, the mobile station sends a handover announcement (S 5.3) to the first network to offer it an opportunity to improve the operational parameters for the communication through the first network. The first network (1) may in response offer updated operational parameters (S5.6) with a view to encouraging the communication to continue through the first network. A decision (S5.7) whether to make a handover to the second network can then be made by comparing the updated operational parameters for the first network with the operational parameters for the second network.Type: GrantFiled: March 15, 2006Date of Patent: January 13, 2015Assignee: British Telecommunications Public Limited CompanyInventors: Rory S Turnbull, David R Wisely, Peter P Smyth
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Publication number: 20140314728Abstract: The present invention provides biomarkers for sensitive, specific, accurate and quantitative diagnosis and assessment of chronic hypoxia. In particular, the present invention provides 2-hydroxyglutarate as a biomarker that is differentially produced in chronic hypoxia. Furthermore, embodiments of the invention are able to differentiate between chronic and acute hypoxia. Assays for levels of 2-hydroxyglutarate may be used alone or in conjunction with additional biomarkers of hypoxia to increase the precision of analysis. In particular embodiments of the invention, the level of 2-hydroxyglutarate and at least one second biomarker may be assayed to generate a hypoxic profile that can be compared to a reference or control profile, thereby diagnosing a subject as normoxic, chronically hypoxic, or acutely hypoxic.Type: ApplicationFiled: November 18, 2012Publication date: October 23, 2014Inventors: David R. Wise, Patrick S. Ward, Craig B. Thompson
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Patent number: 8767617Abstract: A mobile station MS1 can communicate through a PLMN (2) and also through a number of local wireless networks e.g. WLAN (6) and WiMAX (7). When the user of MS1 wishes to run an application, for example an video player application, a suitable one of the networks is selected for the communication by obtaining data from the candidate networks using SIP INVITE messages that produce responses containing network parameter data for each of the candidate networks. The handset MS1 may also monitor local network traffic to determine network congestion and also check past history to determine whether many handovers have been made during previous sessions. The data is collated and checked with a service provider (10) so that a network selection decision can be made.Type: GrantFiled: March 24, 2006Date of Patent: July 1, 2014Assignee: BRITISH TELECOMMUNICATIONS public limited companyInventor: David R Wisely
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Publication number: 20110301153Abstract: The invention concerns methods of treating cancer comprising contacting said tumors with a chemical inhibitor of glutaminolysis. These inhibitors include amino-oxyacetate, phenylbutyrate, phenylacetate, and 3,7-bis(dimethylamino)-phenazathionium chloride (methylene blue).Type: ApplicationFiled: November 16, 2009Publication date: December 8, 2011Applicant: The Trustees of the University of PennsylvaniaInventors: Craig B. Thompson, David R. Wise
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Patent number: 7907529Abstract: In order to keep a pathway for time critical data packets (for example for VoIP calls) a dummy flow of data packets is established between a home hub router (20) and a broadband remote access server (25) being the first gateway to the IP network. Should a call be made from the telephone (23), the dummy flow is replaced for the duration of the call by the packets generated for the VoIP call. The dummy flow is adjusted by increasing or decreasing the number of data packets transmitted in order to ensure that a minimum bandwidth having a tolerable delay is available. The dummy flow works by causing non time critical (i.e. P2P data packet flows) to back off and no modification is required to routers and the like incorporated into the network.Type: GrantFiled: February 28, 2007Date of Patent: March 15, 2011Assignee: British Telecommunications public limited companyInventors: David R Wisely, Rory S Turnbull, Richard Gedge
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Publication number: 20100085943Abstract: A connection between a communications terminal and a communications network is arranged such that on detection of imminent degradation or loss of such connection, the utilization of the connection is maximized in advance of such degradation. The network temporarily reallocates the maximum bandwidth that the terminal is capable of using to that terminal, which may result in a small temporary degradation of the bandwidth available to other terminals, and the terminal downloads the data most likely to be required next to a cache (in the case of specific web pages, identified by recent accession, bookmarks, or hyperlinks from the page currently being viewed), or a buffer (if the data is being streamed) using this extra bandwidth made available.Type: ApplicationFiled: January 16, 2008Publication date: April 8, 2010Inventors: Gidon Moshe Reid, David R. Wisely, Rory S. Turnbull
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Publication number: 20090265775Abstract: The present invention relates to authenticating a mobile device using location information associated with the device. The present invention provides a mechanism for authenticating a mobile device based on location related information or a “logical location”, but without requiring an actual location. The mobile user device gathers tokens such as SIM data from other wireless devices using wireless communication between the user device and the other devices. A server determines whether these tokens match predetermined reference information, and if so authenticates the user device.Type: ApplicationFiled: March 15, 2006Publication date: October 22, 2009Applicant: BRITISH TELECOMMUNICATIONS PUBLIC LIMITED COMPANYInventors: David R. Wisely, Rory S. Turnbull
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Publication number: 20090232088Abstract: A mobile station MS1 can communicate through a PLMN (2) and also through a number of local wireless networks e.g. WLAN (6) and WiMAX (7). When the user of MS1 wishes to run an application, for example an video player application, a suitable one of the networks is selected for the communication by obtaining data from the candidate networks using SIP INVITE messages that produce responses containing network parameter data for each of the candidate networks. The handset MS1 may also monitor local network traffic to determine network congestion and also check past history to determine whether many handovers have been made during previous sessions. The data is collated and checked with a service provider (10) so that a network selection decision can be made.Type: ApplicationFiled: March 24, 2006Publication date: September 17, 2009Inventor: David R Wisely
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Publication number: 20090059811Abstract: In order to keep a pathway for time critical data packets (for example for VoIP calls) a dummy flow of data packets is established between a home hub router (20) and a broadband remote access server (25) being the first gateway to the IP network. Should a call be made from the telephone (23), the dummy flow is replaced for the duration of the call by the packets generated for the VoIP call. The dummy flow is adjusted by increasing or decreasing the number of data packets transmitted in order to ensure that a minimum bandwidth having a tolerable delay is available. The dummy flow works by causing non time critical (i.e. P2P data packet flows) to back off and no modification is required to routers and the like incorporated into the network.Type: ApplicationFiled: February 28, 2007Publication date: March 5, 2009Inventors: David R. Wisely, Rory S. Turnbull, Richard Gedge
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Publication number: 20090029703Abstract: When a mobile station MS1 determines during communication through a first network (1), that a second network (7) is available that offers better operational parameters for the communication, the mobile station sends a handover announcement (S 5.3) to the first network to offer it an opportunity to improve the operational parameters for the communication through the first network. The first network (1) may in response offer updated operational parameters (S5.6) with a view to encouraging the communication to continue through the first network. A decision (S5.7) whether to make a handover to the second network can then be made by comparing the updated operational parameters for the first network with the operational parameters for the second network.Type: ApplicationFiled: March 15, 2006Publication date: January 29, 2009Inventors: Rory S. Turnbull, David R. Wisely, Peter P. Smyth
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Patent number: 6425211Abstract: This invention relates to a novel self-closing fire rated floor door. More particularly, this invention pertains to a novel floor door which uses fusible plugs and compressed gas cylinders for automatically closing the floor door when ambient temperature rises above a predetermined temperature, due to a fire. A self-closing fire rated floor door assembly comprising: (a) a fire rated frame with an opening therethrough; (b) a fire rated door hingedly connected to the frame and cooperating with the opening; (c) a fluid cylinder which is pivotally connected to the frame and the door, the cylinder when pressurized with fluid opening the door relative to the frame, and when depressurized, closing the door relative to the frame; (d) a fusible plug, rated according to a specific temperature, connected in fluid-tight manner with the fluid cylinder.Type: GrantFiled: November 20, 2000Date of Patent: July 30, 2002Assignee: Maxam Metal Products Ltd.Inventors: David R. Wise, Alfred G. Craig, Jerome E. Beck