Patents by Inventor David Ralph
David Ralph has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250148214Abstract: A neuro-symbolic retrieval augmented generation hybrid method includes detecting an incomplete entigen group within a knowledge database. The incomplete entigen group includes entigens and one or more entigen relationships between at least some of the entigens. The incomplete entigen group represents knowledge of a topic. The method further includes obtaining additive content for the topic based on the incomplete entigen group and generating an additive entigen group based on the additive content. The method further includes updating the incomplete entigen group utilizing the additive entigen group to produce an updated entigen group. The method further includes indicating that the updated entigen group has an un-curated status when the additive entigen group conflicts with the incomplete entigen group.Type: ApplicationFiled: January 9, 2025Publication date: May 8, 2025Applicant: entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Donald Joseph Wurzel, Paige Kristen Thompson, Stephen Emerson Sundberg, Ameeta Vasant Reed, Stephen Chen, Dennis Arlen Roberson, Thomas James MacTavish, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Theodore Mazurkiewicz, Gary W. Grube
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Patent number: 12287818Abstract: A method includes determining a set of identigens for each word of at least some words of a string of words of a query to produce a plurality of sets of identigens. The method further includes interpreting, based on a first knowledge database, the plurality of sets of identigens to produce a first entigen group and generating a first preliminary query response based on the first entigen group. The method further includes interpreting, based on a second knowledge database, the plurality of sets of identigens to produce a second entigen group and generating a second preliminary query response based on the second entigen group. The method further includes comparing the first and second preliminary query responses and when the first preliminary query response and the second preliminary query response are divergent, resolving inconsistencies between the first and second preliminary query responses to produce a final query response.Type: GrantFiled: December 24, 2018Date of Patent: April 29, 2025Assignee: entigenlogic LLCInventors: Frank John Williams, Andrew Chu, Dennis Arlen Roberson, David Ralph Lazzara, Donald Joseph Wurzel
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Publication number: 20250110980Abstract: A method performed by a computing device includes generating a neural network representation of a subjective query and generating a query entigen group as a symbolic architecture representation of the subjective query. The method further includes identifying one or more characteristic entigen categories for a subjective category entigen of the query entigen group. The method further includes generating a symbolic architecture representation of a query response for the subjective query that includes a set of response entigens based on the one or more characteristic entigen categories. The set of response entigens provides an answer for the subjective query.Type: ApplicationFiled: December 13, 2024Publication date: April 3, 2025Applicant: entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Stephen Emerson Sundberg, Ameeta Vasant Reed, Dennis Arlen Roberson, Thomas James MacTavish, Karl Olaf Knutson, Jessy Thomas, Niklas Josiah MacTavish, David Michael Corns, II, Andrew Chu, Theodore Mazurkiewicz, Gary W. Grube
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Publication number: 20250094415Abstract: A method executed by a computing device includes determining that a set of words are included in a word set. The method further includes determining a set of identigens for each word of the word set to produce sets of identigens, where a set of identigens of the sets of identigens represents one or more different meanings of a word of the word set. The method further includes interpreting, using identigen pairing rules, the sets of identigens to produce an entigen set. The method further includes assigning a single new entigen to represent the entigen set, where the single new entigen represents a most likely meaning interpretation of the word set.Type: ApplicationFiled: December 6, 2024Publication date: March 20, 2025Applicant: Entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Donald Joseph Wurzel, Paige Kristen Thompson, Stephen Emerson Sundberg, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Eric Andrew Faurie, Theodore Mazurkiewicz, Gary W. Grube
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Publication number: 20250077560Abstract: A method includes selecting an entigen group from a knowledge database. The entigen group is a most likely meaning of a phrase of a string of words. An entigen of the entigen group corresponds to a selected identigen from a set of identigens regarding a word of the string of words. The set of identigens represent different meanings of the word. The method further includes identifying other entigen groups of alternate phrases having a similar most likely meaning from the knowledge database. The alternate phrases are different permutations of the string of words. The method further includes determining a dominant sentiment the other entigen groups and generating an updated clarifying entigen group based on the sentiment.Type: ApplicationFiled: November 20, 2024Publication date: March 6, 2025Applicant: entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Gary W. Grube, Stephen Emerson Sundberg
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Publication number: 20250077900Abstract: A method executed by a computing device includes determining to extend knowledge within a knowledge database for an object represented by linked entigens of an entigen group based on a deficiency of the entigen group. The method further includes determining a set of identigens for each word of a phrase associated with the object to produce sets of identigens. The method further includes interpreting the sets of identigens to determine a most likely meaning interpretation of the phrase and produce a new entigen group. The method further includes updating the entigen group utilizing the new entigen group to produce a curated entigen group such that a deficiency of the entigen group is resolved providing more accurate and more complete knowledge of the object.Type: ApplicationFiled: November 15, 2024Publication date: March 6, 2025Applicant: entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Donald Joseph Wurzel, Paige Kristen Thompson, Stephen Emerson Sundberg, Ameeta Vasant Reed, Stephen Chen, Dennis Arlen Roberson, Thomas James MacTavish, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Theodore Mazurkiewicz, Gary W. Grube
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Patent number: 12243093Abstract: Described is a system and method for routing output information to one or more of a plurality of output devices. In one implementation, output information that includes information to be presented and a location information identifying where the output information is to be presented may be generated by an output host. The output information is received by an output router that determines, based on the location information, an output device and routes the output information to the output device for presentation.Type: GrantFiled: December 12, 2019Date of Patent: March 4, 2025Assignee: Amazon Technologies, Inc.Inventors: Alexander Michael McNamara, Nathan Lee Wesling, Natalie Thuy-Tien Nguyen, Jack Bradley Jones, Felix Joseph Etienne Pageau, Lu Ye, Kevin Alexander Lee, Sridhar Boyapati, Benjamin Ralph Hollis, David William Bettis, Kirk Arlo Petersen, Korwin Jon Smith
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Patent number: 12230420Abstract: Bundled cables and methods for preparing bundled cable are disclosed herein. In the method, a plurality of subunits is wound about a central member. The subunits include a subunit jacket made of a first thermoplastic composition and has a first outer surface, and the central member includes a central member jacket made of a second thermoplastic composition and has a second outer surface. A metal element is provided at an interface of the second outer surface and the first outer surface of the subunits. The metal element is heated such that at least one of the first thermoplastic composition or the second thermoplastic composition forms bonds with the other of the first thermoplastic composition or the second thermoplastic composition.Type: GrantFiled: September 12, 2023Date of Patent: February 18, 2025Assignee: CORNING RESEARCH & DEVELOPMENT CORPORATIONInventors: David Ralph Maack, Lars Kristian Nielsen, James Arthur Register, William Taylor Rowell
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Patent number: 12204863Abstract: A method includes detecting an incomplete entigen group within a knowledge database. The incomplete entigen group includes entigens and one or more entigen relationships between at least some of the entigens. The incomplete entigen group represents knowledge of a topic. The method further includes obtaining additive content for the topic based on the incomplete entigen group and generating an additive entigen group based on the additive content. The method further includes updating the incomplete entigen group utilizing the additive entigen group to produce an updated entigen group. The method further includes indicating that the updated entigen group has an un-curated status when the additive entigen group conflicts with the incomplete entigen group.Type: GrantFiled: March 24, 2022Date of Patent: January 21, 2025Assignee: entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Donald Joseph Wurzel, Paige Kristen Thompson, Stephen Emerson Sundberg, Ameeta Vasant Reed, Stephen Chen, Dennis Arlen Roberson, Thomas James MacTavish, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Theodore Mazurkiewicz, Gary W. Grube
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Patent number: 12178829Abstract: Provided are compounds, compositions, methods, and kits for increasing target specificity of a mannosylated carbohydrate polymeric therapeutic or diagnostic compound to reduce or eliminate localization of the mannosylated carbohydrate polymeric therapeutic or diagnostic compound to off-target sites. Mannosylated carbohydrate polymers are synthesized to be modified to be either polyanionic (i.e., net negatively charged) or electrostatically neutral, and using these polyanionic or neutral mannosylated carbohydrate polymers as competitors for polycationic (i.e., net positively charged) mannosylated carbohydrate polymers carrying small molecule drug payloads or imaging moieties to CD206 expressing cells in target tissues, such as tumors or other sites of inflammation.Type: GrantFiled: October 27, 2023Date of Patent: December 31, 2024Assignee: Navidea Biopharmaceuticals, Inc.Inventors: David A. Ralph, Jeffrey Scott Arnold
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Patent number: 12182188Abstract: A method performed by a computing device includes determining a set of identigens for each word of words of a subjective query to produce sets of identigens. The method further includes interpreting, using identigen pairing rules of a knowledge database, the sets of identigens to determine a most likely meaning interpretation of the subjective query and produce a query entigen group that includes query entigens. The method further includes identifying one or more characteristic entigen categories for a subjective category entigen of the query entigen group. The method further includes recovering a set of response entigens for the subjective query from the knowledge database utilizing the query entigen group and based on the one or more characteristic entigen categories. The set of response entigens provides an answer for the subjective query.Type: GrantFiled: July 26, 2022Date of Patent: December 31, 2024Assignee: entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Stephen Emerson Sundberg, Ameeta Vasant Reed, Dennis Arlen Roberson, Thomas James MacTavish, Karl Olaf Knutson, Jessy Thomas, Niklas Josiah MacTavish, David Michael Corns, II, Andrew Chu, Theodore Mazurkiewicz, Gary W. Grube
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Patent number: 12164507Abstract: A method executed by a computing device includes determining whether a set of words are included in a word set. When the set of words are in the word set, the method further includes determining a set of identigens for each word of the word set to produce sets of identigens, where a set of identigens of the sets of identigens represents one or more different meanings of a word of the word set. The method further includes interpreting, using identigen pairing rules, the sets of identigens to produce an entigen set. The method further includes assigning a single new entigen to represent the entigen set, where the single new entigen represents a most likely meaning interpretation of the word set.Type: GrantFiled: April 10, 2023Date of Patent: December 10, 2024Assignee: entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Donald Joseph Wurzel, Paige Kristen Thompson, Stephen Emerson Sundberg, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Eric Andrew Faurie, Theodore Mazurkiewicz, Gary W. Grube
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Publication number: 20240386703Abstract: A method for execution by a computing device includes obtaining a set of media element identigens for media elements of media to produce sets of media element identigens. The sets of media element identigens are possible interpretations of a media element. The method further includes generating a set of relationships between media elements. The relationships provide a list of one or more ways in which the media elements are related. The method further includes processing different permutations of the sets of media element identigens using the set of relationships to generate textual descriptions as a proxy for an entigen group. The entigen group represents a most likely interpretation of the media.Type: ApplicationFiled: July 26, 2024Publication date: November 21, 2024Applicant: entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Gary W. Grube
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Patent number: 12147907Abstract: A method executed by a computing device includes determining to update an entigen group within a knowledge database, where the entigen group includes a set of linked entigens that represent knowledge associated with an object. The method further includes determining a set of identigens for each word of a phrase associated with the object to produce sets of identigens. The method further includes interpreting the sets of identigens to determine a most likely meaning interpretation of the phrase and produce a new entigen group. The method further includes updating the entigen group utilizing the new entigen group to produce a curated entigen group such that a deficiency of the entigen group is resolved providing more accurate and more complete knowledge of the object.Type: GrantFiled: February 10, 2022Date of Patent: November 19, 2024Assignee: entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Donald Joseph Wurzel, Paige Kristen Thompson, Stephen Emerson Sundberg, Ameeta Vasant Reed, Stephen Chen, Dennis Arlen Roberson, Thomas James MacTavish, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Theodore Mazurkiewicz, Gary W. Grube
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Publication number: 20240294564Abstract: Provided are novel compounds containing a polymeric carbohydrate backbone, one or more mannose-binding C-type lectin receptor targeting moieties, and a nitrogenous bisphosphonate compound coupled to the backbone via a thiol-maleimide conjugation, in addition to pharmaceutical compositions, methods of synthesizing, and methods of use. The thiol-maleimide conjugation of a bisphosphonate to a polymeric carbohydrate backbone provides for methods of using the compounds and compositions thereof for releasing the therapeutic payload when internalized into a mannose-binding C-type lectin receptor-expressing cell, such as tumor associated macrophages (TAMs) for the treatment of various diseases, including, cancer, autoimmune diseases, and inflammatory disorders.Type: ApplicationFiled: May 15, 2024Publication date: September 5, 2024Inventors: David A. Ralph, Jeffrey Scott Arnold
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Patent number: 12056914Abstract: A method for execution by a computing device includes obtaining a set of media element identigens for media elements of media to produce sets of media element identigens. The sets of media element identigens are possible interpretations of a media element. The method further includes generating a set of relationships between media elements. The relationships provide a list of one or more ways in which the media elements are related. The method further includes processing different permutations of the sets of media element identigens using the set of relationships to generate an entigen group. The entigen group represents a most likely interpretation of the media.Type: GrantFiled: August 17, 2021Date of Patent: August 6, 2024Assignee: entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Stephen Chen, Karl Olaf Knutson, Jessy Thomas, David Michael Corns, II, Andrew Chu, Gary W. Grube
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Publication number: 20240249161Abstract: A method performed by a computing device includes generating a comparative query entigen group set based on a comparative query in accordance with identigen rules, where the comparative query entigen group set represents a most likely interpretation of the comparative query. The method further includes obtaining a first response entigen group from a knowledge database based on a first comparative query entigen group of the comparative query entigen group set. The method further includes obtaining a second response entigen group from the knowledge database based on a second comparative query entigen group of the comparative query entigen group set. The method further includes generating a comparative response based on the first response entigen group and the second response entigen group.Type: ApplicationFiled: April 4, 2024Publication date: July 25, 2024Applicant: entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Stephen Emerson Sundberg, Ameeta Vasant Reed, Dennis Arlen Roberson, Thomas James MacTavish, Karl Olaf Knutson, Jessy Thomas, Niklas Josiah MacTavish, David Michael Corns, II, Andrew Chu, Theodore Mazurkiewicz, Gary W. Grube
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Publication number: 20240202445Abstract: A method for execution by a computing device includes identifying sets of identigens for words of a phrase. The method further includes selecting, based on identigen pairing rules of a knowledge database, a first identigen of a first set of identigens for a first word that pairs with at least one corresponding sequentially adjacent identigen of a second set of identigens. The method further includes selecting the first identigen of the first set of identigens as a subsequent identigen corresponding to a subsequent occurrence of the first word within the sequence of words. The method further includes interpreting, in accordance with the identigen pairing rules and based on the first identigen selection for the subsequent occurrence of the first word, the sets of identigens to produce an entigen group that represents a most likely meaning interpretation of the phrase.Type: ApplicationFiled: January 3, 2024Publication date: June 20, 2024Applicant: entigenlogic LLCInventors: Frank John Williams, David Ralph Lazzara, Donald Joseph Wurzel, Stephen Emerson Sundberg, Ameeta Vasant Reed, Dennis Arlen Roberson, Thomas James MacTavish, Karl Olaf Knutson, Jessy Thomas, Niklas Josiah MacTavish, David Michael Corns, II, Andrew Chu, Theodore Mazurkiewicz, Gary W. Grube
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Patent number: 12006339Abstract: Provided are novel compounds containing a polymeric carbohydrate backbone, one or more mannose-binding C-type lectin receptor targeting moieties, and a nitrogenous bisphosphonate compound coupled to the backbone via a thiol-maleimide conjugation, in addition to pharmaceutical compositions, methods of synthesizing, and methods of use. The thiol-maleimide conjugation of a bisphosphonate to a polymeric carbohydrate backbone provides for methods of using the compounds and compositions thereof for releasing the therapeutic payload when internalized into a mannose-binding C-type lectin receptor-expressing cell, such as tumor associated macrophages (TAMs) for the treatment of various diseases, including, cancer, autoimmune diseases, and inflammatory disorders.Type: GrantFiled: May 19, 2023Date of Patent: June 11, 2024Assignee: Navidea Biopharmaceuticals, Inc.Inventors: David A. Ralph, Jeffrey Scott Arnold
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Patent number: RE50354Abstract: A method of detecting patterns in network traffic is provided. The method includes receiving packets of network traffic, performing a frequency analysis per field of the packets as a function of frequency of the occurrence of the same data in the corresponding field, and selecting top values which are values associated with each field of the set of fields that satisfy a criterion as having occurred most frequently in the packets as a function of a result of the frequency analysis.Type: GrantFiled: August 24, 2023Date of Patent: March 25, 2025Assignee: Arbor Networks, Inc.Inventors: Steinthor Bjarnason, Andrew Ralph Beard, David Turnbull