Abstract: This invention concerns performing clinical tissue examination with a device that includes sensors which produces signals in response to pressure imposed on the sensors as the sensors are pressed against the tissue. The sensors generate signals in response to pressure imposed on the sensors when pressed against a selected region of tissue. That pressure varies in accordance with properties of underlying tissue structures. An image of the region of tissue is generated based on the signals generated by the sensors. The image is then displayed. The image represents the pressure imposed on the sensors. The image that is displayed may be a three dimensional image of the region of tissue. The signals produced by the sensors can also be processed to detect an underlying tissue structure in the region of tissue. A location or a map of the detected underlying tissue structure relative to a reference point is generated and displayed. The results of a current examination are compared to those of a previous examination.

Abstract: A device is provided for diagnosis and treatment of tissue with instruments, specifically locating a tissue structure and positioning an instrument relative to that tissue structure. The device which includes a plurality of sensors for generating signals in response to pressure imposed on the sensors as the sensors are pressed against the tissue. The device which includes a member which is configured to be pressed against tissue and the sensors are disposed on the member, for detection of an underlying tissue structure in the tissue. The device also includes a locating device, arranged at a selected position with respect to the sensors, for indicating a location of the underlying tissue structure. An image based on the sensors may be displayed. The method of using the device includes positioning the locating device, which may be an instrument guide, over an underlying tissue structure based on the image.