Patents by Inventor David Reed Helton

David Reed Helton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF CYPROHEPTADINE TO TREAT ORGANOPHOSPHATE EXPOSURE
    Publication number: 20200085808
    Abstract: A method of treating exposure to an organophosphate compound by administering a cyproheptadine compound to a subject in need thereof.
    Type: Application
    Filed: August 29, 2019
    Publication date: March 19, 2020
    Inventors: David Reed Helton, David Brian Fick
  • Treatment of organophosphate exposure with ocinaplon
    Patent number: 10478438
    Abstract: A method of treating exposure to organophosphate agents and preventing morbidity due to such exposure through the administration of a pyrazolopyrimidine compound such as ocinaplon, zaleplon, indiplon, or divaplon.
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: November 19, 2019
    Inventors: David Reed Helton, Ernest Pfadenhauer
  • Use of cyproheptadine to treat organophosphate exposure
    Patent number: 10398687
    Abstract: A method of treating exposure to an organophosphate compound by administering a cyproheptadine compound to a subject in need thereof.
    Type: Grant
    Filed: September 14, 2011
    Date of Patent: September 3, 2019
    Inventors: David Reed Helton, David Brian Fick
  • TREATMENT OF ORGANOPHOSPHATE EXPOSURE WITH TETRAHYDROINDOLONE ARYLPIPERAZINE COMPOUNDS
    Publication number: 20150051219
    Abstract: A method of treating exposure to organophosphate agents through the use of compounds comprising tetrahydroindolone and arylpiperazine moieties.
    Type: Application
    Filed: July 28, 2014
    Publication date: February 19, 2015
    Inventors: David Reed HELTON, David Brian FICK
  • Assay for determination of compounds having anti-emetic activity
    Patent number: 8637263
    Abstract: A screening method for identifying compounds with anti-emetic properties by evaluating binding affinity and efficacy of the compounds with respect to the 5-HT1a, 5-HT1d, and 5-HT7 receptors.
    Type: Grant
    Filed: October 14, 2011
    Date of Patent: January 28, 2014
    Assignee: Epiomed Therapeutics, Inc.
    Inventors: David Reed Helton, David Brian Fick, Ernest H. Pfadenhauer
  • TREATMENT OF ORGANOPHOSPHATE EXPOSURE WITH TRIPTANS
    Publication number: 20140024641
    Abstract: A method of treating exposure to organophosphate agents and preventing morbidity due to such exposure through the administration of a triptan compound to a subject.
    Type: Application
    Filed: January 7, 2013
    Publication date: January 23, 2014
    Inventors: David Reed HELTON, David Brian FICK, Ernest H. PFADENHAUER, James LUCOT
  • Tetrahydroindolone derivatives for treatment of neurological conditions
    Patent number: 8598180
    Abstract: Compositions comprising tetrahydroindolone derivatives in which the tetrahydroindolone moiety is covalently linked to a substituted arylpiperazine moiety and methods for treating neurological and psychiatric conditions using such compositions are disclosed.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: December 3, 2013
    Assignee: Abraxis Bioscience, Inc.
    Inventors: David Reed Helton, David Brian Fick, Jason Paul Sharp, Ernest H. Pfadenhauer
  • TREATMENT OF ORGANOPHOSPHATE EXPOSURE WITH OCINAPLON
    Publication number: 20110245275
    Abstract: A method of treating exposure to organophosphate agents and preventing morbidity due to such exposure through the administration of a pyrazolopyrimidine compound such as ocinaplon, zaleplon, indiplon, or divaplon.
    Type: Application
    Filed: October 16, 2009
    Publication date: October 6, 2011
    Inventor: David Reed Helton
  • Compositions for treating pain
    Patent number: 6936601
    Abstract: The present invention provides compositions for treating pain using an atypical antipsychotic compound that is seroquel in combination with another Drug Used in the Treatment of Pain.
    Type: Grant
    Filed: August 15, 2002
    Date of Patent: August 30, 2005
    Assignee: Eli Lilly and Company
    Inventors: David Reed Helton, Harlan E. Shannon, Daniel E. Womer, Mary Jeanne Kallman
  • Method for treating pain
    Publication number: 20030013689
    Abstract: The present invention provides a method for treating pain using an atypical antipsychotic compound.
    Type: Application
    Filed: August 15, 2002
    Publication date: January 16, 2003
    Inventors: David Reed Helton, Harlan E. Shannon, Daniel E. Womer, Mary Jeanne Kallman
  • 3-substituted Bicyclo?3.1.0!hexane-6-carboxylic acids
    Patent number: 5916920
    Abstract: Compounds of the formula ##STR1## in which X represents a bond, S, O or NR.sup.a ; and R is as defined in the specification are useful as modulators of metabotropic glutamate receptor function.
    Type: Grant
    Filed: November 14, 1996
    Date of Patent: June 29, 1999
    Assignee: Eli Lilly and Company
    Inventors: Carmen Dominguez Fernandez, David Reed Helton, Steven Marc Massey, James Allen Monn
  • Anxiolytic agents
    Patent number: 5882671
    Abstract: The present invention provides a method of treating anxiety and related disorders using an agonist which acts at negatively coupled cAMP-linked metabotropic glutamate receptors.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: March 16, 1999
    Assignee: Eli Lilly and Company
    Inventors: David Reed Helton, Mary Jeanne Kallman, James Allen Monn, Darryle Darwin Schoepp, Joseph Patrick Tizzano