Patents by Inventor David Rekosh

David Rekosh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds that Inhibit HIV Particle Formation
    Publication number: 20110152301
    Abstract: The present invention describes novel methods of identifying compounds which inhibit HIV particle formation and Rev-dependent HIV production. The present invention also provides methods and compounds for inhibiting HIV particle formation and or treating patients infected with HIV.
    Type: Application
    Filed: December 22, 2010
    Publication date: June 23, 2011
    Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: David Rekosh, Marie-Louise Hammarskjöld
  • Compounds that inhibit HIV particle formation
    Patent number: 7875604
    Abstract: The present invention describes novel methods of identifying compounds which inhibit HIV particle formation and Rev-dependent HIV production. The present invention also provides methods and compounds for inhibiting HIV particle formation and or treating patients infected with HIV.
    Type: Grant
    Filed: February 1, 2005
    Date of Patent: January 25, 2011
    Assignee: University of Virginia Patent Foundation
    Inventors: David Rekosh, Marie-Louise Hammarskjöld
  • Compounds that Inhibit Hiv Particle Formation
    Publication number: 20080318959
    Abstract: The present invention describes novel methods of identifying compounds which inhibit HIV particle formation and Rev-dependent HIV production. The present invention also provides methods and compounds for inhibiting HIV particle formation and or treating patients infected with HIV.
    Type: Application
    Filed: February 1, 2005
    Publication date: December 25, 2008
    Inventors: David Rekosh, Marie-Louise Hammarskjold
  • Purified retroviral constitutive transport enhancer elements that enhance nucleocytoplasmic transport of mRNA, and methods of making and using the elements
    Patent number: 5880276
    Abstract: A novel retroviral nucleotide sequence comprising a constitutive transport enhancer which functions to transport mRNA transcripts from the nucleus to the cytoplasm of a cell, wherein the mRNA transcript is either differentially spliced, alternatively spliced, incompletely spliced, or unspliced. Additionally disclosed are methods of using the constitutive transport enhancer to screen agents for antiviral activity against rev-dependent HIV proteins by expressing the proteins in a rev-negative subgenomic construct containing the enhancer either in the presence of absence of the agent.
    Type: Grant
    Filed: April 25, 1996
    Date of Patent: March 9, 1999
    Assignees: The Research Foundation of the State University of NY, University of Alabama at Birmingham Research Foundation
    Inventors: Marie-Louise Hammarskjold, David Rekosh, Molly Bray, Eric Hunter
  • Purified retroviral constitutive transport enhancer and its use to facilitate mRNA transport, and to produce recombinant, attenuated HIV
    Patent number: 5585263
    Abstract: A novel retroviral nucleotide sequence comprising a constitutive transport enhancer which functions to transport mRNA transcripts from the nucleus to the cytoplasm of a cell, wherein the mRNA transcript is either differentially spliced, alternatively spliced, incompletely spliced, or unspliced. Also disclosed is a recombinant attenuated HIV containing only structural proteins gag, pol, and env, wherein the expression of the structural proteins is rev-independent and facilitated by the constitutive transport enhancer.
    Type: Grant
    Filed: May 20, 1994
    Date of Patent: December 17, 1996
    Assignees: University of Alabama at Birmingham Research Foundation, Research Foundation of State University of New York
    Inventors: Marie-Louise Hammarskj old, David Rekosh, Molly Bray, Eric Hunter