Patents by Inventor David Renwick Houck

David Renwick Houck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the treatment and prevention of ocular disorders
    Patent number: 8551952
    Abstract: Provided herein are methods for treatment of ocular diseases. The methods comprise administering a compound of general Formula (I): wherein R1, R2, R3, R4 and Ak are as defined in the specification.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: October 8, 2013
    Assignee: Scynexis, Inc.
    Inventor: David Renwick Houck
  • Macrocycles
    Patent number: 8536114
    Abstract: Disclosed herein are compounds of general formula (I): wherein A, B, R1 and R2 are as defined in the specification, and their use as pharmaceuticals.
    Type: Grant
    Filed: December 30, 2009
    Date of Patent: September 17, 2013
    Assignee: Scynexis, Inc.
    Inventors: Keqiang Li, David Renwick Houck, Cyprian Okwara Ogbu, Michael Robert Peel, Andrew William Scribner
  • Arylalkyl and heteroarylalkyl derivatives of cyclosporine A for the treatment and prevention of viral infection
    Patent number: 8329658
    Abstract: This invention provides compounds of general formula (I): wherein A, B, R1, R2 and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus and/or human immunodeficiency virus.
    Type: Grant
    Filed: October 2, 2006
    Date of Patent: December 11, 2012
    Assignee: Scynexis, Inc.
    Inventors: David Renwick Houck, Keqiang Li
  • METHODS FOR THE TREATMENT AND PREVENTION OF OCULAR DISORDERS
    Publication number: 20120270804
    Abstract: Provided herein are methods for treatment of ocular diseases. The methods comprise administering a compound of general Formula (I): wherein R1, R2, R3, R4 and Ak are as defined in the specification.
    Type: Application
    Filed: April 27, 2012
    Publication date: October 25, 2012
    Inventor: David Renwick Houck
  • 3-ETHER AND 3-THIOETHER SUBSTITUTED CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF HEPATITIS C INFECTION
    Publication number: 20120264679
    Abstract: This invention relates to cyclosporin derivatives of general formula (I): wherein A, B, R1, R2 and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus.
    Type: Application
    Filed: June 20, 2012
    Publication date: October 18, 2012
    Applicant: SCYNEXIS, INC.
    Inventors: Hans Georg Fliri, David Renwick Houck
  • Method for the treatment and prevention of ocular disorders
    Patent number: 8188052
    Abstract: Provided herein are methods for treatment of ocular diseases. The methods comprise administering a compound of general Formula (I): wherein R1, R2, R3, R4 and Ak are as defined in the specification.
    Type: Grant
    Filed: May 18, 2007
    Date of Patent: May 29, 2012
    Assignee: Scynexis, Inc.
    Inventor: David Renwick Houck
  • Methods and pharmaceutical compositions for the treatment and prevention of hepatitis C infection
    Patent number: 7754685
    Abstract: This invention relates to cyclosporin derivatives of general formula (I): wherein A, B, R1, R2 and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus.
    Type: Grant
    Filed: October 2, 2006
    Date of Patent: July 13, 2010
    Assignee: Scynexis, Inc.
    Inventor: David Renwick Houck
  • NOVEL MACROCYCLES
    Publication number: 20100173836
    Abstract: Disclosed herein are compounds of general formula (I): wherein A, B, R1 and R2 are as defined in the specification, and their use as pharmaceuticals.
    Type: Application
    Filed: December 30, 2009
    Publication date: July 8, 2010
    Inventors: Keqiang Li, David Renwick Houck, Cyprian Okwara Ogbu, Michael Robert Peel, Andrew William Scribner
  • 3-Ether and 3-Thioether Substituted Cyclosporin Derivatives For the Treatment and Prevention of Hepatitis C Infection
    Publication number: 20100167996
    Abstract: This invention relates to cyclosporin derivatives of general formula (I): wherein A, B, R1, R2 and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus.
    Type: Application
    Filed: December 21, 2009
    Publication date: July 1, 2010
    Inventors: Hans Georg Fliri, David Renwick Houck
  • 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
    Patent number: 7718767
    Abstract: This invention relates to cyclosporin derivatives of general formula (I): wherein A, B, R1, R2 and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus.
    Type: Grant
    Filed: March 21, 2006
    Date of Patent: May 18, 2010
    Assignee: Scynexis, Inc.
    Inventors: Hans Georg Fliri, David Renwick Houck
  • METHOD FOR THE TREATMENT AND PREVENTION OF OCULAR DISORDERS
    Publication number: 20100062975
    Abstract: Provided herein are methods for treatment of ocular diseases. The methods comprise administering a compound of general Formula (I): wherein R1, R2, R3, R4 and Ak are as defined in the specification.
    Type: Application
    Filed: May 18, 2007
    Publication date: March 11, 2010
    Inventor: David Renwick Houck
  • Arylalkyl and Heteroarylalkyl Derivaties of Cyclosporine a for the Treatment and Prevention of Viral Infection
    Publication number: 20090298751
    Abstract: This invention provides compounds of general formula (T): (I) wherein A, B, R1, R2, and X are as defined in this specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus and/or human immunodeficiency virus.
    Type: Application
    Filed: October 2, 2006
    Publication date: December 3, 2009
    Applicant: SCYNEXIS, INC.
    Inventors: David Renwick Houck, Keqiang Li
  • Cyclic peptides
    Patent number: 7576057
    Abstract: The invention relates to novel cyclic peptide derivatives of general formula (I): wherein A, B, R1 and R2 are as defined in the specification, pharmaceutically acceptable salts thereof, and their use as pharmaceuticals, in particular for the treatment of hepatitis C virus.
    Type: Grant
    Filed: November 19, 2007
    Date of Patent: August 18, 2009
    Assignee: Scynexis, Inc.
    Inventors: Andrew William Scribner, David Renwick Houck
  • Novel cyclic peptides
    Publication number: 20080171699
    Abstract: The invention relates to novel cyclic peptide derivatives of general formula (I): wherein A, B, R1 and R2 are as defined in the specification, pharmaceutically acceptable salts thereof, and their use as pharmaceuticals, in particular for the treatment of hepatitis C virus.
    Type: Application
    Filed: November 19, 2007
    Publication date: July 17, 2008
    Inventors: Andrew William Scribner, David Renwick Houck
  • 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
    Patent number: 7196161
    Abstract: This invention relates to cyclosporin derivatives of general formula (I): wherein A, B, R1, R2 and X are as defined in the specification, and pharmaceutical compositions prepared from the same, for use in treatment of hepatitis C virus.
    Type: Grant
    Filed: September 30, 2005
    Date of Patent: March 27, 2007
    Assignee: Scynexis Inc.
    Inventors: Hans Georg Fliri, David Renwick Houck