Patents by Inventor David Rezac
David Rezac has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11951270Abstract: Systems and methods for implanting an endovascular shunt in a patient is disclosed. The system having an expandable anchor configured for being deployed in a dural venous sinus of a patient at a location distal to a curved portion of a wall of an inferior petrosal sinus (IPS) of the patient; an elongate guide member coupled to, and extending proximally from, the anchor; a shunt delivery catheter having a first lumen configured to receive the guide member, and a second lumen extending between respective proximal and distal openings in the shunt delivery catheter, the shunt delivery catheter further having a penetrating element coupled to a distal end of the catheter; and the system further having a guard at least partially disposed over, and movable relative to, the penetrating element.Type: GrantFiled: August 5, 2020Date of Patent: April 9, 2024Assignee: CereVasc, LLCInventors: Adel M. Malek, Carl Heilman, David A. Rezac, Jack B. Sattell, Anthony Maiorano
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Patent number: 11850390Abstract: Endovascular drug delivery systems and methods are disclosed herein for delivering a therapeutic agent to the intracranial subarachnoid space of a patient, and/or deploying an endovascular drug delivery device distal portion in the intracranial subarachnoid space and a portion of the drug delivery device body in a dural venous sinus such that a therapeutic agent is delivered from the deployed drug delivery device into the intracranial subarachnoid space.Type: GrantFiled: May 11, 2021Date of Patent: December 26, 2023Assignee: Cerevasc, Inc.Inventors: Adel M. Malek, Carl B. Heilman, David A. Rezac, Jack B. Sattell, Alexander Bonin
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Publication number: 20230389924Abstract: The invention provides systems, devices, and methods for the delivery, deployment, and positioning of magnetic compression devices at a desired site so as to improve the accuracy of anastomoses creation between tissues, organs, or the like.Type: ApplicationFiled: August 21, 2023Publication date: December 7, 2023Inventors: Dane Seddon, Peter Lukin, Jonathan B. O'Keefe, Amos Cruz, Jeffrey C. Cerier, Keith D. Boudreau, Taylor Bensel, David A. Rezac
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Patent number: 11771875Abstract: In some aspects, catheter devices can include: a reinforcing member having a proximal and distal ends, the reinforcing member comprising: discrete longitudinally arranged structural regions between the proximal and distal ends comprising: a first, proximal, structural region defining a first series of wall perforations that generate structural properties within the first structural region, the first series of wall perforations setting a first stiffness of the first structural region; and a second structural region, disposed distally relative to the first structural region, defining a second series of wall perforations that generate structural properties within the second structural region, the second series of wall perforations setting a second stiffness of the second structural region, which is less than the first stiffness, wherein the second series of wall perforations differs from the first series of wall perforations by at least one of: cut balance, cut frequency, or pitch.Type: GrantFiled: March 2, 2018Date of Patent: October 3, 2023Assignee: CereVasc, Inc.Inventors: Adel M. Malek, Carl Heilman, David A. Rezac, Jack B. Sattell, Alexander Bonin
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Patent number: 11751877Abstract: The invention provides systems, devices, and methods for the delivery, deployment, and positioning of magnetic compression devices at a desired site so as to improve the accuracy of anastomoses creation between tissues, organs, or the like.Type: GrantFiled: December 1, 2020Date of Patent: September 12, 2023Assignee: G.I. Windows, Inc.Inventors: Dane Seddon, Peter Lukin, Jonathan B. O'Keefe, Amos Cruz, Jeffrey C. Cerier, Keith D. Boudreau, Taylor Bensel, David A. Rezac
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Publication number: 20230255768Abstract: Disclosed herein is an expandable sheath that can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. The disclosed herein sheath can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some aspects can include a sheath comprising an inner layer comprising a reinforcing layer comprising a plurality of struts that can be encapsulated within a polymer layer comprising a tether portion and an outer layer disposed over the inner layer. The disclosed sheath is configured to locally expand from a predetermined first diameter d1 to an expanded second diameter d2 during application of a radial outward force by passage of a medical device through the sheath.Type: ApplicationFiled: April 25, 2023Publication date: August 17, 2023Inventors: Ilan Tamir, David A. Rezac, Devin H. Marr, Jack Sattell, Michelle Riches, Bridget Bergstrom, Matthew Lapointe
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Publication number: 20230256195Abstract: Aspects of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such aspects can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some aspects can include a sheath comprising an inner layer comprising a reinforcing layer rolled into a spiral slidable configuration and encapsulated within a polymer layer comprising a tether portion and an outer layer disposed over the inner layer. The disclosed sheath is configured to locally expand from a predetermined first diameter d1 to an expanded second diameter d2 during application of a radial outward force by passage of the medical device through the sheath.Type: ApplicationFiled: April 21, 2023Publication date: August 17, 2023Inventors: Ilan Tamir, Devin H. Marr, David A. Rezac, Michelle Riches, Bridget Bergstrom, Julia Stoddard
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Publication number: 20230256213Abstract: An apparatus for loading an endovascular shunt into a delivery catheter includes a base, a boss rod connected to, and extending longitudinally across, the base, and a plurality of guide bosses slidably coupled to the boss rod. The guide bosses include a delivery catheter guide boss coupled to the delivery catheter, a malecot holding tube guide boss, wherein a malecot holding tube is connected to a first lateral side of the malecot guide boss extending towards the delivery catheter guide boss, a claw assembly guide boss, where a claw assembly is attached to a first lateral side of the claw guide boss extending towards the malecot holding tube guide boss, and a chase pin guide boss, wherein a chase pin is connected to a first lateral side of the chase pin guide boss extending towards the claw assembly guide boss.Type: ApplicationFiled: March 28, 2023Publication date: August 17, 2023Applicant: CEREVASC, INC.Inventors: Jack B. Sattell, David A. Rezac, Alexander Bonin
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Publication number: 20230233820Abstract: Systems and methods for implanting an endovascular shunt in a patient is disclosed. The system having an expandable anchor configured for being deployed in a dural venous sinus of a patient at a location distal to a curved portion of a wall of an inferior petrosal sinus (IPS) of the patient; an elongate guide member coupled to, and extending proximally from, the anchor; a shunt delivery catheter having a first lumen configured to receive the guide member, and a second lumen extending between respective proximal and distal openings in the shunt delivery catheter, the shunt delivery catheter further having a penetrating element coupled to a distal end of the catheter; and the system further having a guard at least partially disposed over, and movable relative to, the penetrating element.Type: ApplicationFiled: March 30, 2023Publication date: July 27, 2023Applicant: CEREVASC, INC.Inventors: Adel M. Malek, Carl Heilman, David A. Rezac, Jack B. Sattell, Anthony Maiorano
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Publication number: 20230218338Abstract: Apparatus for performing a minimally-invasive procedure, the apparatus comprising: a shaft having a distal end and a proximal end; a monopolar knife assembly attached to the distal end of the shaft, the monopolar knife assembly comprising a knife; a handle attached to the proximal end of the shaft; wherein the shaft comprises a flexible portion and an articulating portion, wherein the flexible portion extends distally from the handle and the articulating portion extends distally from the flexible portion; wherein at least one articulation cable extends from the handle to the articulating portion, such that when tension is applied to the at least one articulation cable, the articulating portion deflects; wherein an actuation element extends through the shaft from the handle to the knife, such that when the actuation element is moved, the knife is moved; and wherein the actuation element transmits electrical power from the handle to the knife.Type: ApplicationFiled: September 20, 2022Publication date: July 13, 2023Inventors: Jonathan O'Keefe, Jeffrey Cerier, Amos Cruz, David Rezac, Niklas Helmick, Peter Aliski, Andrew Caunter
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Patent number: 11633578Abstract: An apparatus for loading an endovascular shunt into a delivery catheter includes a base, a boss rod connected to, and extending longitudinally across, the base, and a plurality of guide bosses slidably coupled to the boss rod. The guide bosses include a delivery catheter guide boss coupled to the delivery catheter, a malecot holding tube guide boss, wherein a malecot holding tube is connected to a first lateral side of the malecot guide boss extending towards the delivery catheter guide boss, a claw assembly guide boss, where a claw assembly is attached to a first lateral side of the claw guide boss extending towards the malecot holding tube guide boss, and a chase pin guide boss, wherein a chase pin is connected to a first lateral side of the chase pin guide boss extending towards the claw assembly guide boss.Type: GrantFiled: January 23, 2021Date of Patent: April 25, 2023Assignee: CereVasc, Inc.Inventors: Jack B. Sattell, David A. Rezac, Alexander Bonin
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Patent number: 11446081Abstract: Apparatus for performing a minimally-invasive procedure, the apparatus comprising: a shaft having a distal end and a proximal end; a monopolar knife assembly attached to the distal end of the shaft, the monopolar knife assembly comprising a knife; a handle attached to the proximal end of the shaft; wherein the shaft comprises a flexible portion and an articulating portion, wherein the flexible portion extends distally from the handle and the articulating portion extends distally from the flexible portion; wherein at least one articulation cable extends from the handle to the articulating portion, such that when tension is applied to the at least one articulation cable, the articulating portion deflects; wherein an actuation element extends through the shaft from the handle to the knife, such that when the actuation element is moved, the knife is moved; and wherein the actuation element transmits electrical power from the handle to the knife.Type: GrantFiled: February 3, 2020Date of Patent: September 20, 2022Assignee: Lumedi Ltd.Inventors: Jonathan O'Keefe, Jeffrey Cerier, Amos Cruz, David Rezac, Niklas Helmick, Peter Aliski, Andrew Caunter
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Publication number: 20220280276Abstract: There is disclosed a porous emboli deflector for preventing cerebral emboli while maintaining cerebral blood flow during an endovascular or open surgical procedure. The device prevents the entrance of emboli of a size able to cause stroke (such as greater than 100 microns) from entering either the right or left common carotid arteries, and/or the right or left vertebral arteries by deflecting emboli downstream of these vessels. The device can be placed prior to any manipulation of the heart or aorta allowing maximal protection of the brain during the index procedure. The deflector has a low profile within the aorta which allows sheaths, catheters, or wires used in the index procedure to pass. Also disclosed are methods for insertion and removal of the deflector.Type: ApplicationFiled: May 24, 2022Publication date: September 8, 2022Inventors: Judith T. Carpenter, Jeffrey P. Carpenter, David A. Rezac, Jeffrey C. Cerier, Richard C. Fortier, Timothy W. Robinson
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Publication number: 20220265292Abstract: A method and apparatus for delivery of cell therapies, introduced via percutaneous access to the circulation, and delivered to the site of vascular injury or intervention.Type: ApplicationFiled: August 31, 2020Publication date: August 25, 2022Inventors: Judith T. Carpenter, Jeffrey P. Carpenter, Spencer Brown, Jack B. Sattell, David A. Rezac, Devin H. Marr, Camron Garrett
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Patent number: 11376031Abstract: Apparatus for performing a minimally-invasive procedure, the apparatus comprising: a tool comprising: a shaft having a distal end and a proximal end; a handle attached to the proximal end of the shaft; and an end effector attached to the distal end of the shaft; wherein the shaft comprises a flexible portion extending distally from the proximal end of the shaft, and an articulating portion extending proximally from the distal end of the shaft, and wherein the articulating portion comprises a flexible spine; wherein a plurality of articulation cables extend through the shaft from the handle to the flexible spine, such that when tension is applied to at least one of the plurality of articulation cables, the flexible spine bends; wherein a rotatable element extends through the shaft from the handle to the end effector, such that when the rotatable element is rotated, the end effector rotates; and wherein an actuation element extends through the shaft from the handle to the end effector, such that when the actuatType: GrantFiled: April 13, 2020Date of Patent: July 5, 2022Assignee: Lumendi Ltd.Inventors: Jonathan O'Keefe, Jeffrey Cerier, Amos Cruz, David Rezac
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Publication number: 20210268252Abstract: Endovascular drug delivery systems and methods are disclosed herein for delivering a therapeutic agent to the intracranial subarachnoid space of a patient, and/or deploying an endovascular drug delivery device distal portion in the intracranial subarachnoid space and a portion of the drug delivery device body in a dural venous sinus such that a therapeutic agent is delivered from the deployed drug delivery device into the intracranial subarachnoid space.Type: ApplicationFiled: May 11, 2021Publication date: September 2, 2021Applicant: CEREVASC, INC.Inventors: Adel M. Malek, Carl B. Heilman, David A. Rezac, Jack B. Sattell, Alexander Bonin
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Publication number: 20210228846Abstract: An apparatus for loading an endovascular shunt into a delivery catheter includes a base, a boss rod connected to, and extending longitudinally across, the base, and a plurality of guide bosses slidably coupled to the boss rod. The guide bosses include a delivery catheter guide boss coupled to the delivery catheter, a malecot holding tube guide boss, wherein a malecot holding tube is connected to a first lateral side of the malecot guide boss extending towards the delivery catheter guide boss, a claw assembly guide boss, where a claw assembly is attached to a first lateral side of the claw guide boss extending towards the malecot holding tube guide boss, and a chase pin guide boss, wherein a chase pin is connected to a first lateral side of the chase pin guide boss extending towards the claw assembly guide boss.Type: ApplicationFiled: January 23, 2021Publication date: July 29, 2021Applicant: CEREVASC, INC.Inventors: Jack B. Sattell, David A. Rezac, Alexander Bonin
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Patent number: 11013900Abstract: Endovascular drug delivery systems and methods are disclosed herein for delivering a therapeutic agent to the intracranial subarachnoid space of a patient, and/or deploying an endovascular drug delivery device distal portion in the intracranial subarachnoid space and a portion of the drug delivery device body in a dural venous sinus such that a therapeutic agent is delivered from the deployed drug delivery device into the intracranial subarachnoid space.Type: GrantFiled: March 8, 2019Date of Patent: May 25, 2021Assignee: CereVasc, Inc.Inventors: Adel M. Malek, Carl B. Heilman, David A. Rezac, Jack B. Sattell, Alexander Bonin
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Publication number: 20210100554Abstract: The invention provides systems, devices, and methods for the delivery, deployment, and positioning of magnetic compression devices at a desired site so as to improve the accuracy of anastomoses creation between tissues, organs, or the like.Type: ApplicationFiled: December 1, 2020Publication date: April 8, 2021Inventors: Dane Seddon, Peter Lukin, Jonathan B. O'Keefe, Amos Cruz, Jeffrey C. Cerier, Keith D. Boudreau, Taylor Bensel, David A. Rezac
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Publication number: 20200406018Abstract: Endovascular drug delivery systems and methods are disclosed herein for delivering a therapeutic agent to the intracranial subarachnoid space of a patient, and/or deploying an endovascular drug delivery device distal portion in the intracranial subarachnoid space and a portion of the drug delivery device body in a dural venous sinus such that a therapeutic agent is delivered from the deployed drug delivery device into the intracranial subarachnoid space.Type: ApplicationFiled: March 8, 2019Publication date: December 31, 2020Applicant: CEREVASC, INC.Inventors: Adel M. Malek, Carl B. Heilman, David A. Rezac, Jack B. Sattell, Alexander Bonin