Abstract: A lens element intended to be worn in front of an eye of a wearer including at least a first and a second set of optical elements providing respectively a first and a second optical function. When worn by a wearer, an optical element of the first set is located at a greater distance from the center of rotation of the eye than an optical element of the second set. At least some optical elements of the second set are disposed with respect to the optical elements of the first set of the lens element to provide according to a respective first and a second gaze direction on different zones of the retina of the eye of the wearer distinct cumulative optical effects.

Abstract: A lens element intended to be worn in front of an eye of a wearer having at least a first and a second set of optical elements providing respectively a first and a second optical function. When worn by a wearer, an optical element of the first set is located at a greater distance from the center of rotation of the eye than an optical element of the second set. At least some of the optical elements of the first set and the second set are disposed in a mutual relationship in such a way that, for at least one gaze direction, a first and a second cumulative optical effect are provided at the same time for respective at least first and second incoming light beams.

Abstract: A lens element to be worn by a wearer and to provide a refractive power based on a prescription of the wearer is provided for correcting an abnormal refraction of the eye of the wearer, the lens element including: an optical microstructure having an optical function of not focusing an image on a retina of the eye of the wearer so as to slow down progression of the abnormal refraction of the eye of the wearer, in which a modulation transfer function of the lens element is greater or equal to 0.07 over a range of spatial frequencies from 10 to 25 cycles per degree, when measured through the optical microstructure for a pupil aperture of 4 mm centered at 6.6 mm from the optical center of the lens element. A computer-implemented method for determining a lens element to be worn by a wearer is also provided.

Abstract: A lens element to be worn by a wearer and to provide a refractive power based on a prescription of the wearer is provided for correcting an abnormal refraction of the eye of the wearer, the lens element including: an optical microstructure having an optical function of not focusing an image on a retina of the eye of the wearer so as to slow down the progression of the abnormal refraction, in which the modulation transfer function of the lens element, for peripheral vision, is less than or equal to 0.8 over a range of spatial frequency comprised from 3 to 7 cycles per degree, when measured through the optical microstructure for a pupil aperture of 4 mm centered at 6.6 mm from the optical center of the lens element. A computer-implemented method for determining a lens element to be worn by a wearer is also provided.

Abstract: A method implemented by a computer means includes: obtaining a lens design; the lens design representing the variation of optical aberrations as a function of the angular view point; obtaining a set of subjective values representing the sensitivity of the user to a set of optical aberrations; and correlating the set of subjective values and the lens design based on the variation of optical aberrations so as to produce correlation information, advantageously for determining to which extent the lens design is adapted to the user from the correlation.

Abstract: An injection aid system and a social aid system having a computing system with at least one processor and a memory device. The computing system can be configured to generate a at least one of a virtual environment and an augmented environment. A display device can be coupled to the computing system and configured to visually display the environment. The injection aid system can further include an injection tool and a treatment target configured to receive a simulated injection by the injection tool. The injection tool can have a needle and a plunger.

Abstract: An injection aid system and a social aid system having a computing system with at least one processor and a memory device. The computing system can be configured to generate a at least one of a virtual environment and an augmented environment. A display device can be coupled to the computing system and configured to visually display the environment. The injection aid system can further include an injection tool and a treatment target configured to receive a simulated injection by the injection tool. The injection tool can have a needle and a plunger.

Abstract: Embodiments of the present invention are directed to the oral administration of Bryostatins for the treatment of neuro-degenerative disease.

Abstract: The instant invention is related with new perimidine derivatives synthesized via direct condensation between naphthalene-1,8-diamine and itaconic or citraconic anhydrides at low temperature. The targeting itaco-perinone (IP) molecule formed via double low temperature cyclization has fluorescence properties emitting white light intensively. Besides, 9-methylene-8H-pyrrolo[1,2-a]perimidin-10(9H)-one is copolymerizable with several kind of organic monomer compounds via free radical mechanism maintaining the ability to emit white light even within the polymer film.

Abstract: An embodiment includes a holder assembly with terminals that are supported by insert molding. The terminals are electrically connector to conductors, which can be covered with an insulative covering, and thus provide easy to connector holder assemblies. The holder can include features that allow an LED module to be inserted into a recess in the housing and retained via a friction fit. Such a configuration allows the assembly to be shipped as an assembly without the need to solder the LED module to the holder and while still ensuring a reliable electrical connection between the LED module and the corresponding holder assembly.

Abstract: An embodiment includes a holder assembly with terminals that are supported by insert molding. The terminals are electrically connector to conductors, which can be covered with an insulative covering, and thus provide easy to connector holder assemblies. The holder can include features that allow an LED module to be inserted into a recess in the housing and retained via a friction fit. Such a configuration allows the assembly to be shipped as an assembly without the need to solder the LED module to the holder and while still ensuring a reliable electrical connection between the LED module and the corresponding holder assembly.

Abstract: An embodiment includes a holder assembly with terminals that are supported by insert molding. The terminals are electrically connector to conductors, which can be covered with an insulative covering, and thus provide easy to connector holder assemblies. The holder can include features that allow an LED module to be inserted into a recess in the housing and retained via a friction fit. Such a configuration allows the assembly to be shipped as an assembly without the need to solder the LED module to the holder and while still ensuring a reliable electrical connection between the LED module and the corresponding holder assembly.

Abstract: An injection aid system and a social aid system having a computing system with at least one processor and a memory device. The computing system can be configured to generate a at least one of a virtual environment and an augmented environment. A display device can be coupled to the computing system and configured to visually display the environment. The injection aid system can further include an injection tool and a treatment target configured to receive a simulated injection by the injection tool. The injection tool can have a needle and a plunger.

Abstract: The instant invention is related with new perimidine derivatives synthesized via direct condensation between naphthalene-1,8-diamine and itaconic or citraconic anhydrides at low temperature. The targeting itaco-perinone (IP) molecule formed via double low temperature cyclization has fluorescence properties emitting white light intensively. Besides, 9-methylene-8H-pyrrolo[1,2-a]perimidin-10(9H)-one is copolymerizable with several kind of organic monomer compounds via free radical mechanism maintaining the ability to emit white light even within the polymer film.

Abstract: An embodiment includes a holder assembly with terminals that are supported by insert molding. The terminals are electrically connector to conductors, which can be covered with an insulative covering, and thus provide easy to connector holder assemblies. The holder can include features that allow an LED module to be inserted into a recess in the housing and retained via a friction fit. Such a configuration allows the assembly to be shipped as an assembly without the need to solder the LED module to the holder and while still ensuring a reliable electrical connection between the LED module and the corresponding holder assembly.

Abstract: Embodiments of the present invention are directed to the oral administration of Bryostatins for the treatment of neuro-degenerative disease.

Abstract: Embodiments of the present invention are directed to the oral administration of Bryostatins for the treatment of neuro-degenerative disease.

Abstract: The present invention relates to a process for hardening an aluminum-based matrix alloy by the dispersion of metallized graphite (MG) with copper and optionally zinc or boron by the agitation in liquid state. By this means, the impregnating of MG particles (reinforcing phase) is increased, facilitating the homogenous distribution in the aluminum-base matrix alloy. The mechanical properties of aluminum or aluminum-based are increased alloys by the process of hardening by dispersion, without affecting the density and electrical conductivity of the alloy.

Abstract: The invention concerns a device (D) dedicated to managing media server resources (MSj) in a communication network (CR), adapted to provide sets of media functions for providing the media parts of the requested services to client communication terminals (T) requesting services, comprising at least one media part, managed by application servers (ASi). Said device (D) comprises storage means (BD) storing data representative of media functions matching the media server identifiers (MSj) and managing means (MG) adapted, upon receiving a message from an application server (ASi) dedicated to a service requested by a client terminal (T) and requiring the provision of a set of media functions for providing a media part of the requested service, to determine the identifier of a media server (MSj) having the resources for offering the requested set, in the storage means (BD), then allocate resources of said media server (MSj) so that the message may be transmitted thereto.

Abstract: A system and method for generating and managing a generic mortgage-backed securities index. Bonds are selected for the index on a monthly basis. In order to determine which bonds will be represented in the index during a particular month, a set of calculations is performed during the second business week of the preceding month. For the purpose of selecting bonds for the index, all outstanding mortgage-backed securities are considered. They are first aggregated into pools based on their coupon and original term, and then their total outstanding principals are considered. If the total principal outstanding of any 30-year coupon represents more than a predetermined percentage such as 1.5% of the total, then this 30-year coupon will be included in the Index. Similarly, if the total principal outstanding on any 15-year coupon represents more than a second predetermined percentage such as 0.4% of the total, then this 15-year coupon will be included in the Index.