Abstract: Systems and methods are disclosed for detecting Cherenkov radiation produced during radiotherapy. A radiotherapy system comprises a patient receiving space for receiving a patient, a therapeutic radiation source, and a light detector configured to detect Cherenkov radiation subsequent to the emission of therapeutic radiation. Optionally, the system may make use of a optically transmissive dielectric to produce Cherenkov radiation.

Abstract: Drivetrain assemblies for personal care devices using electromagnetic components to generate a combination of controllable power tapping and sweeping motions. The drivetrain assemblies include a drivetrain shaft at least partially contained within a body portion of the device. The drivetrain shaft is further configured to engage a brush head member of the device. The drivetrain assemblies further include a motor mounted on the drivetrain shaft, where the motor is configured to periodically rotate the drivetrain shaft about a first axis of the device, and an electromagnetic assembly configured to drive the drivetrain shaft and thereby the brush head member about an second axis of the device or in a direction parallel to a third axis of the device. The electromagnetic assembly includes a stator, a voice coil actuator, a rotor, or a linear solenoid actuator, for example.

Abstract: A cutting element assembly includes a cutter support including a cutter bore. A cutting element is in the cutter bore and a resilient element is integral with the cutter support. The resilient element is longitudinally compressible and has a displacement of greater than 0.1 mm and optionally less than 2 mm. Another cutting assembly includes a cutter support coupled to multiple cutting elements. A resilient element of the cutter support is compressible based on a force applied to the cutter support through one or more of the cutting elements. The resilient element can include a slit in the cutter support. A slit may, for instance, extend perpendicular or transverse to an axis of the cutting elements and allow the cutter support to flex and close off or reduce a size of the slit when forces act on one or more of the cutting elements.

Abstract: A biomarker detection apparatus in which a CMOS-based chip is used to generate independent detection signals from a reaction zone that receives a biological sample, where the biological sample is provided to both a test region and positive and negative control regions within the reaction zone. The independent detection signals can be processed together (i.e. as a group of input parameters for an algorithm) to identify the presence of a biomarker (or a plurality of biomarkers) in a biological sample. The use of sample-specific, independently detectable positive and negative controls facilitates improved detection accuracy.

Abstract: A medical device that includes a body and a polymer matrix over the body. The polymer matrix includes a plurality of fibers defining a plurality of pores to permit tissue growth therethrough. The medical device includes a bio-adhesive coating at least partially covering the polymer matrix.

Abstract: A method for analyzing planar sample is provided. In some cases the method comprises: (a) labelling the planar sample with a capture agent that is linked to a nucleic acid, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the nucleic acid, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided.

Abstract: A fluid flow structure for a washing machine is located within a wash tank of the washing machine, which includes a fluid flow guide surface, and a support for the guide surface. The guide surface includes at least one region contoured inconsistently from the contour of at least one corresponding wall of the washing machine wash tank. The contour of the guide surface is generally curved so as to aide in reducing and/or preventing the pinning of items that often occurs in rectangular wash tanks of the prior art. The support for the guide surface creates a gap between the guide surface and at least one wall of the washing machine wash tank.

Abstract: An electrical heater, an exhaust treatment assembly, and method of manufacture. The heater includes a resistive portion configured to generate heat when electrical current is passed therethrough. A plurality of slots extend into the resistive portion from an outer periphery of the resistive portion and define a serpentine current-carrying path extending through the resistive portion between a pair of electrode attachment portions. Each of the electrode attachment portions is connected to a respective end segment that is bounded between an outer periphery of the resistive portion and a respective first slot of the plurality of slots. At least one auxiliary slot in each of the end segments that extends from the outer periphery toward the first slot in a direction transverse to the first slot to bias current flow through a concentrated region adjacent to and extending along the first slot in each end segment.

Abstract: Techniques are described herein that are capable of automatically generating a workflow using responses to AI-generated inquiries as inputs to a generative AI model. An initial prompt from a user is provided as an input to a generative AI model. The initial prompt indicates that a task is to be completed. Inquiries are provided in a first successive order to the user. The inquiries are generated by the generative AI model based at least on the initial prompt. The inquiries solicit information regarding the task. Response prompts are received in a second successive order that corresponds to the first successive order. The response prompts are responses to the respective inquiries. The generative AI model is caused to automatically generate a workflow, which is configured to achieve the task, based at least on the response prompts.

Abstract: There is described an apparatus for heating an aerosol generating material to generate an inhalable aerosol and/or gas. The apparatus comprises a housing; a receptacle within the housing, the receptacle comprising one or more cavities, each cavity for containing an aerosol generating material; and a heating arrangement comprising one or more heater elements for heating aerosol generating material contained in the one or more cavities to generate an inhalable aerosol and/or gas. The one or more heater elements are located externally of the one or more cavities.

Abstract: Some embodiments provide for an inspiratory limb for a breathing circuit that includes a first segment that comprises a first heater wire circuit and a second segment that comprises a second heater wire circuit. The inspiratory limb can include an intermediate connector that includes a connection circuit that electrically couples the first heater wire circuit to the second heater wire circuit. The inspiratory limb can be configured to operate in two modes wherein, in a first mode, electrical power passes through the first electrical connection to provide power to the first heater wire circuit without providing power to the second heater wire circuit, and in a second mode, electrical power pass through the first electrical connection to provide power to both the first heater wire circuit and the second heater wire circuit.

Abstract: Devices, systems and techniques are used for cancer treatment. An example control device may be configured to be communicatively coupled to a radiation source of a radiotherapy device and a position sensor of the radiotherapy device. The example control device may be used to calculate, for a sliding window of a radiotherapy treatment, a positional error between: a measured target position signal determined from a series of images and sampled at the acquisition times of the images, and an estimated target position signal. The example control device may generate a computer-executable instruction configured to alter the radiotherapy treatment in response to the positional error violating a threshold.

Abstract: Systems, apparatuses, and methods disclosed herein are provided for a motorized implant delivery system. The delivery system may utilize a processor for control of at least one motor for actuating a delivery apparatus. The delivery system may include sensors configured sense one or more of a condition of the patient's body or a condition of the delivery apparatus. The processor may process the signals provided by the sensors, which may comprise feedback signals to the processor.

Abstract: A coating composition includes: (a) a polymeric resin including hydroxyl functional groups; (b) a polyisocyanate crosslinker; (c) a thiol including at least 2 active hydrogen groups, where the active hydrogen groups include a thiol group or a combination of a thiol and a hydroxyl group; and (d) a tin-based catalyst. The ratio of the number of moles of thiol to the number of moles of tin in the coating composition is less than or equal to 100:1 and the amount of (d) the tin-based catalyst is less than or equal to 0.25% by weight relative to the total resin solids, and/or the ratio of the number of moles of thiol to the number of moles of tin ranges from 3:1 to 50:1 and the amount of (d) the tin-based catalyst is less than or equal to 0.4% by weight relative to the total resin solids.

Abstract: A catalytic partial wall-flow filter suitable for use in an exhaust gas treatment system, a method of making the catalytic partial wall-flow filter, and a method of using the catalytic partial wall-flow filter to remediate engine exhaust streams are disclosed. The filter comprises a partial wall-flow filter substrate having an inlet end, an outlet end, and a plurality of porous walls forming channels from the inlet end to the outlet end, wherein some of the channels are plugged channels and some are unplugged flow-through channels. A selective catalytic reduction (SCR) catalyst is coated on the porous walls.

Abstract: The present disclosure provides methods for selecting a patient diagnosed with amyotrophic lateral sclerosis (ALS) for an ALS therapy, methods for assessing a ALS patient's likely responsiveness to an ALS therapy, methods for treating an ALS patient with an ALS therapy, methods for monitoring efficacy of an ALS therapy, and methods for assessing the likely progression of ALS in a patient, in which methods serum concentrations of one or more serum immune-based biomarkers are determined.

Abstract: Optimizing beamforming overhead and improving coverage in a radio access network in a wireless communications system (WCS) is disclosed. Herein, a radio node(s) is configured to radiate multiple radio frequency (RF) beams in a coverage area. Notably, the RF beams can intercept a ground since the radio node(s) is mounted above the ground (e.g., on a ceiling) and facing downward toward the ground. As a result, some of the radiated energy may be wasted to degrade coverage and performance in the coverage area. In this regard, in embodiments disclosed herein, multiple reflector devices (passive and/or active) are provided in proximity to the radio node(s) to intercept the RF beams radiated from the radio node(s) and redirect the intercepted RF beams in parallel to the ground. By redirecting the RF beams horizontally, it is possible to reduce energy waste and enhance beamforming coverage in the radio access network.

Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.

Abstract: A cutting element assembly includes a cutter support including a cutter bore. A cutting element is in the cutter bore and a resilient element is integral with the cutter support. The resilient element is longitudinally compressible and has a displacement of greater than 0.1 mm and optionally less than 2 mm. Another cutting assembly includes a cutter support coupled to multiple cutting elements. A resilient element of the cutter support is compressible based on a force applied to the cutter support through one or more of the cutting elements. The resilient element can include a slit in the cutter support. A slit may, for instance, extend perpendicular or transverse to an axis of the cutting elements and allow the cutter support to flex and close off or reduce a size of the slit when forces act on one or more of the cutting elements.