Patents by Inventor David Robert McIlwain

David Robert McIlwain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ON-SLIDE STAINING BY PRIMER EXTENSION
    Publication number: 20240035068
    Abstract: A method for analyzing planar sample is provided. In some cases the method comprises: (a) labelling the planar sample with a capture agent that is linked to a nucleic acid, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the nucleic acid, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided.
    Type: Application
    Filed: March 2, 2023
    Publication date: February 1, 2024
    Inventors: Nikolay Samusik, Garry P. Nolan, Yury Goltsev, David Robert McIlwain
  • On-slide staining by primer extension
    Patent number: 11634753
    Abstract: A method for analyzing planar sample is provided. In some cases the method comprises: (a) labelling the planar sample with a capture agent that is linked to a nucleic acid, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the nucleic acid, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided.
    Type: Grant
    Filed: February 25, 2021
    Date of Patent: April 25, 2023
    Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Nikolay Samusik, Garry P. Nolan, Yury Goltsev, David Robert McIlwain
  • ON-SLIDE STAINING BY PRIMER EXTENSION
    Publication number: 20220025444
    Abstract: A method for analyzing planar sample is provided. In some cases the method comprises: (a) labelling the planar sample with a capture agent that is linked to a nucleic acid, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the nucleic acid, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided.
    Type: Application
    Filed: February 25, 2021
    Publication date: January 27, 2022
    Inventors: Nikolay Samusik, Garry P. Nolan, Yury Goltsev, David Robert McIlwain
  • On-slide staining by primer extension
    Patent number: 10982263
    Abstract: A method for analyzing planar sample is provided. In some cases the method comprises: (a) labelling the planar sample with a capture agent that is linked to a nucleic acid, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the nucleic acid, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided.
    Type: Grant
    Filed: November 11, 2019
    Date of Patent: April 20, 2021
    Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Nikolay Samusik, Garry P. Nolan, Yury Goltsev, David Robert McIlwain
  • ON-SLIDE STAINING BY PRIMER EXTENSION
    Publication number: 20200063187
    Abstract: A method for analyzing planar sample is provided. In some cases the method comprises: (a) labelling the planar sample with a capture agent that is linked to a nucleic acid, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the nucleic acid, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided.
    Type: Application
    Filed: November 11, 2019
    Publication date: February 27, 2020
    Inventors: Nikolay Samusik, Garry P. Nolan, Yury Goltsev, David Robert McIlwain
  • ON-SLIDE STAINING BY PRIMER EXTENSION
    Publication number: 20170107563
    Abstract: A method for analyzing planar sample is provided. In some cases the method comprises: (a) labelling the planar sample with a capture agent that is linked to a nucleic acid, wherein the capture agent specifically binds to complementary sites in the planar sample; (b) reading a fluorescent signal caused by extension of a primer that is hybridized to the nucleic acid, using fluorescence microscopy. Several implementations of the method, and multiplexed versions of the same, are also provided.
    Type: Application
    Filed: June 19, 2015
    Publication date: April 20, 2017
    Inventors: Nikolay Samusik, Garry P. Nolan, Yury Goltsev, David Robert McIlwain