Patents by Inventor David Rodman
David Rodman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260053811Abstract: This invention provides a method of treating hypertension in a hypertensive subject having a body mass index of at least 30, the method comprising administering to the subject a CYP 11?2 beta hydroxylase inhibitor once or twice per day in an amount sufficient to treat hypertension in the hypertensive subject.Type: ApplicationFiled: August 22, 2023Publication date: February 26, 2026Applicant: Mineralys Therapeutics, Inc.Inventors: David Rodman, Jon Congleton
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Publication number: 20260053812Abstract: This invention provides a method of treating hypertension in a hypertensive subject, the method administering to the subject, an amount of a diuretic and an amount of a CYP 11?2 beta hydroxylase inhibitor once or twice per day, wherein the amounts taken together are sufficient to treat hypertension in the hypertensive subject when taken in combination with other antihypertensive agents. In particular, the method is sufficient to elicit a safe and robust reduction in hypertension (>10 mmHg reduction in systolic blood pressure) in the hypertensive subject.Type: ApplicationFiled: August 22, 2023Publication date: February 26, 2026Applicant: Mineralys Therapeutics, Inc.Inventors: David Rodman, Jon Congleton
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Publication number: 20250099475Abstract: This invention provides method of treating hypertension in a hypertensive subject, the method comprising administering to the subject a CYP 11?2 beta hydroxylase inhibitor once or twice per day in an amount sufficient to inhibit 50% or more of CYP 11?2 beta hydroxylase's activity for 40-60% of a 24-hour period to thereby treat hypertension in the hypertensive subject.Type: ApplicationFiled: January 19, 2023Publication date: March 27, 2025Applicants: Mineralys Therapeutics, Inc., Mitsubishi Tanabe Pharma CorporationInventors: David Rodman, Brian Taylor Slingsby, Jon Congleton, Hidetoshi Shimizu, Yoshiyasu Ota, Madori Orihashi
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Publication number: 20240009201Abstract: The disclosure provides, inter alia, methods to treat hypertension in patients using CYP 11?2 beta hydroxylase inhibitors.Type: ApplicationFiled: October 25, 2021Publication date: January 11, 2024Applicant: Mineralys Therapeutics, Inc.Inventors: Brian Taylor Slingsby, William Connolly Watt, David Rodman
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Patent number: 10669172Abstract: A composition and method for dispersing sulfur, cleaning sulfur deposits, and minimizing foaming in an aqueous system is disclosed. The method may include adding a first sulfur dispersant to process water containing sulfur and dispersing the sulfur. The first sulfur dispersant may include a C5-C25 alkyl polyglycoside. A second sulfur dispersant may also be added to the process water. The second sulfur dispersant may include a polymer of acrylic acid and 2-acrylamido-2-methylpropane sulfonic acid.Type: GrantFiled: August 21, 2018Date of Patent: June 2, 2020Assignee: ECOLAB USA INC.Inventors: Dinesh Mantri, David Rodman, Jasbir S. Gill
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Publication number: 20190359980Abstract: The present invention provides oligonucleotide inhibitors of miR-155 and compositions thereof. The invention further provides methods for treating cancer such as a T cell lymphoma in a subject by administering to the subject an oligonucleotide inhibitor of miR-155. The invention also provides methods for reducing or inhibiting the proliferation of malignant T cells by administering an oligonucleotide inhibitor of miR-155.Type: ApplicationFiled: April 12, 2019Publication date: November 28, 2019Inventors: David RODMAN, Anita SETO, Christina DALBY, Aimee JACKSON, Xuan BEATTY
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Patent number: 10316318Abstract: The present invention provides oligonucleotide inhibitors of miR-155 and compositions thereof. The invention further provides methods for treating cancer such as a T cell lymphoma in a subject by administering to the subject an oligonucleotide inhibitor of miR-155. The invention also provides methods for reducing or inhibiting the proliferation of malignant T cells by administering an oligonucleotide inhibitor of miR-155.Type: GrantFiled: May 10, 2018Date of Patent: June 11, 2019Assignee: MIRAGEN THERAPEUTICS, INC.Inventors: David Rodman, Anita Seto, Christina Dalby, Aimee Jackson, Xuan Beatty
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Publication number: 20190106695Abstract: The present invention provides oligonucleotide inhibitors of miR-155 and compositions thereof. The invention further provides methods for treating cancer such as a T cell lymphoma in a subject by administering to the subject an oligonucleotide inhibitor of miR-155. The invention also provides methods for reducing or inhibiting the proliferation of malignant T cells by administering an oligonucleotide inhibitor of miR-155.Type: ApplicationFiled: May 10, 2018Publication date: April 11, 2019Inventors: David RODMAN, Anita SETO, Christina DALBY, Aimee JACKSON, Xuan BEATTY
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Publication number: 20190062184Abstract: A composition and method for dispersing sulfur, cleaning sulfur deposits, and minimizing foaming in an aqueous system is disclosed. The method may include adding a first sulfur dispersant to process water containing sulfur and dispersing the sulfur. The first sulfur dispersant may include a C5-C25 alkyl polyglycoside. A second sulfur dispersant may also be added to the process water. The second sulfur dispersant may include a polymer of acrylic acid and 2-acrylamido-2-methylpropane sulfonic acid.Type: ApplicationFiled: August 21, 2018Publication date: February 28, 2019Applicant: ECOLAB USA, Inc.Inventors: Dinesh Mantri, David Rodman, Jasbir S. Gill
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Patent number: 10035949Abstract: The present invention generally relates to methods for increasing recovery of crude oil from a subterranean hydrocarbon-containing formation and for removing or inhibiting deposits in a well, the methods comprising contacting an acid composition that comprises a salt of a nitrogen base having a fluoro inorganic anion with the well or the formation.Type: GrantFiled: August 16, 2016Date of Patent: July 31, 2018Assignee: Ecolab USA Inc.Inventors: Jasbir S. Gill, Anthony G. Sommese, Thomas M. Miller, David Rodman
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Patent number: 9994852Abstract: The present invention provides oligonucleotide inhibitors of miR-155 and compositions thereof. The invention further provides methods for treating cancer such as a T cell lymphoma in a subject by administering to the subject an oligonucleotide inhibitor of miR-155. The invention also provides methods for reducing or inhibiting the proliferation of malignant T cells by administering an oligonucleotide inhibitor of miR-155.Type: GrantFiled: September 25, 2017Date of Patent: June 12, 2018Assignee: MIRAGEN THERAPEUTICS, INC.Inventors: David Rodman, Anita Seto, Christina Dalby, Aimee Jackson, Xuan Beatty
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Publication number: 20180127750Abstract: The present invention provides oligonucleotide inhibitors of miR-155 and compositions thereof. The invention further provides methods for treating cancer such as a T cell lymphoma in a subject by administering to the subject an oligonucleotide inhibitor of miR-155. The invention also provides methods for reducing or inhibiting the proliferation of malignant T cells by administering an oligonucleotide inhibitor of miR-155.Type: ApplicationFiled: August 15, 2017Publication date: May 10, 2018Inventors: David RODMAN, Anita SETO, Christina DALBY, Aimee JACKSON, Xuan BEATTY
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Publication number: 20180037890Abstract: The present invention provides oligonucleotide inhibitors of miR-155 and compositions thereof. The invention further provides methods for treating cancer such as a T cell lymphoma in a subject by administering to the subject an oligonucleotide inhibitor of miR-155. The invention also provides methods for reducing or inhibiting the proliferation of malignant T cells by administering an oligonucleotide inhibitor of miR-155.Type: ApplicationFiled: September 25, 2017Publication date: February 8, 2018Inventors: David RODMAN, Anita SETO, Christina DALBY, Aimee JACKSON, Xuan BEATTY
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Patent number: 9771585Abstract: The present invention provides oligonucleotide inhibitors of miR-155 and compositions thereof. The invention further provides methods for treating cancer such as a T cell lymphoma in a subject by administering to the subject an oligonucleotide inhibitor of miR-155. The invention also provides methods for reducing or inhibiting the proliferation of malignant T cells by administering an oligonucleotide inhibitor of miR-155.Type: GrantFiled: June 3, 2016Date of Patent: September 26, 2017Assignee: MIRAGEN THERAPEUTICS, INC.Inventors: David Rodman, Anita Seto, Christina Dalby, Aimee Jackson, Xuan Beatty
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Patent number: 9645557Abstract: A system for geothermal process optimization can include a receiver configured to receive brine conditions sensed at a head of a production well of a geothermal power plant and a first circuit configured to determine an analyte value according to the sensed brine conditions. Also, the system can include a second circuit configured to determine a product dosage value for a product, according to the analyte value, product information, and historical power plant data. The product dosage value can be an amount of the product suggested to adequately prevent buildup, corrosion, or a combination thereof at a given part of the geothermal power plant, such as the production well.Type: GrantFiled: July 11, 2014Date of Patent: May 9, 2017Assignee: ECOLAB USA INC.Inventors: Jasbir S. Gill, David Rodman, Srinivasan Ramanathan, Tin Huynh
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Publication number: 20170051198Abstract: The present invention generally relates to methods for increasing recovery of crude oil from a subterranean hydrocarbon-containing formation and for removing or inhibiting deposits in a well, the methods comprising contacting an acid composition that comprises a salt of a nitrogen base having a fluoro inorganic anion with the well or the formation.Type: ApplicationFiled: August 16, 2016Publication date: February 23, 2017Inventors: Jasbir S. Gill, Anthony G. Sommese, Thomas M. Miller, David Rodman
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Publication number: 20160355814Abstract: The present invention provides oligonucleotide inhibitors of miR-155 and compositions thereof. The invention further provides methods for treating cancer such as a T cell lymphoma in a subject by administering to the subject an oligonucleotide inhibitor of miR-155. The invention also provides methods for reducing or inhibiting the proliferation of malignant T cells by administering an oligonucleotide inhibitor of miR-155.Type: ApplicationFiled: June 3, 2016Publication date: December 8, 2016Inventors: David RODMAN, Anita SETO, Christina DALBY, Aimee JACKSON, Xuan BEATTY
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Publication number: 20160011570Abstract: A system for geothermal process optimization can include a receiver configured to receive brine conditions sensed at a head of a production well of a geothermal power plant and a first circuit configured to determine an analyte value according to the sensed brine conditions. Also, the system can include a second circuit configured to determine a product dosage value for a product, according to the analyte value, product information, and historical power plant data. The product dosage value can be an amount of the product suggested to adequately prevent buildup, corrosion, or a combination thereof at a given part of the geothermal power plant, such as the production well.Type: ApplicationFiled: July 11, 2014Publication date: January 14, 2016Applicant: ECOLAB USA INC.Inventors: Jasbir S. Gill, David Rodman, Srinivasan Ramanathan, Tin Huynh