Patents by Inventor David Roger Moore

David Roger Moore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240082815
    Abstract: In some embodiments, the present disclosure relates to a system. The system includes a substrate and a fluid capture material formed on one or more surfaces of the substrate. The fluid capture material includes a sorbent material that binds one or more fluids, the one or more fluids comprising water, carbon dioxide, sulfur oxides, or a combination thereof. The fluid capture material also includes one or more binder materials, wherein the binder material is at least partially cross-linked.
    Type: Application
    Filed: September 14, 2022
    Publication date: March 14, 2024
    Inventors: Michael Joseph O'Brien, David Roger Moore, William Christopher Alberts, Jingjing Yang, Mark Daniel Doherty, Mark D. Buckley, Jack E. Howson, Bryce E. Lipinski
  • Publication number: 20230358025
    Abstract: A water recovery system including a first fluid stream inlet providing for the flow of a first fluid stream, such as a humidified inlet gas, into the system and a second fluid stream inlet providing for the flow of a second fluid stream, such as a gas having a temperature greater than the humidified inlet gas, into the system. At least one contactor is in fluid communication with the first fluid stream inlet and the second fluid stream inlet.
    Type: Application
    Filed: July 13, 2023
    Publication date: November 9, 2023
    Inventors: David Roger Moore, Vitali Victor Lissianski, Albert Santo Stella, Daniel Jason Erno
  • Patent number: 11754563
    Abstract: A device comprising a modified porous membrane is provided. The modified porous membrane comprises a polymer coating grafted to a porous membrane. The device is used for analyte detection from a biological sample using an immunoassay. The device comprises a sample application zone at one end of the device for applying a biological sample comprising a target analyte; and a detection zone present at another end of the device, downstream of the sample application zone for detecting the target analyte, wherein the detection zone comprises one or more first biomolecules immobilized on a modified porous membrane having a structure of Formula (I).
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: September 12, 2023
    Assignee: GLOBAL LIFE SCIENCES SOLUTIONS OPERATIONS UK LTD
    Inventors: Bing Li, Brian Christopher Bales, David Roger Moore, Jason Michael Nichols, Cathryn Ellen Olsen, William Christopher Alberts, Frank John Mondello
  • Patent number: 11739506
    Abstract: A water recovery system including a first fluid stream inlet providing for the flow of a first fluid stream, such as a humidified inlet gas, into the system and a second fluid stream inlet providing for the flow of a second fluid stream, such as a gas having a temperature greater than the humidified inlet gas, into the system. At least one contactor is in fluid communication with the first fluid stream inlet and the second fluid stream inlet.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: August 29, 2023
    Assignee: General Electric Company
    Inventors: David Roger Moore, Vitali Victor Lissianski, Albert Santo Stella, Daniel Jason Erno
  • Patent number: 11726078
    Abstract: A device for rapid detection of a tuberculosis lipoarabinomannan (TB-LAM) is provided. The device includes a pre-concentrator unit for concentrating the TB-LAM comprising: an ion-exchange medium comprising one or more ligands configured to capture the TB-LAM from the source biological sample, wherein the captured-TB-LAM is eluted from the ion-exchange medium as an eluate comprising a concentrated form of TB-LAM; a cassette; a lateral flow assay unit disposed in the cassette; and an integration unit attached to the pre-concentrator unit and the cassette. The integration unit is configured to operatively couple and de-couple the pre-concentrator unit and the cassette. The pre-concentrator unit and the lateral flow assay unit disposed in the cassette are in a fluidic communication in a coupled form. The device for rapid detection of TB-LAM further comprises a dilutor unit.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: August 15, 2023
    Assignees: General Electric Company, Tokitae LLC
    Inventors: Matthew Jeremiah Misner, Gregory Andrew Grossmann, Cathryn Ellen Olsen, John Richard Nelson, David Roger Moore, Paul Michael Smigelski, Jr., John Thomas Connelly, Benjamin David Grant, Bernhard Hans Weigl
  • Patent number: 11714084
    Abstract: A rapid detection method of a target biomolecule comprising an antigenic moiety is provided. The method includes providing a source biological sample comprising the target biomolecule; contacting the source biological sample to an ion-exchange medium; eluting the captured-target biomolecule from the ion-exchange medium as an eluate, and loading the eluate to a rapid diagnostic testing device comprising an antibody. The eluate comprises a concentrated form of the biomolecule in a solution having a salt concentration greater than 150 mM. A concentration of the target biomolecule in the eluate is in a range from about 2× to 25× compared to a concentration of the biomolecule in the source biological sample. The target biomolecule binds to the antibody under the salt concentration of greater than 150 mM. A device for rapid detection of target biomolecule is also provided.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: August 1, 2023
    Assignee: General Electric Company
    Inventors: Matthew Jeremiah Misner, Gregory Andrew Grossmann, Cathryn Ellen Olsen, John Richard Nelson, Brian Christopher Bales, David Roger Moore, Paul Michael Smigelski, Jr.
  • Patent number: 11555215
    Abstract: An electrospinning approach is disclosed for generating a dissolvable formulation of a reagent of interest in a nanoscale fiber medium. In one embodiment, the nanoscale fibers can incorporate and stabilize biological agents of interest, such as for storage at room temperature for extended periods. In one implementation, the fibers can be produced in a continuous manner and dissolve rapidly.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: January 17, 2023
    Assignee: GLOBAL LIFE SCIENCES SOLUTIONS OPERATIONS UK LTD
    Inventors: Bing Li, David Roger Moore, William Christopher Alberts, John Richard Nelson
  • Publication number: 20220250002
    Abstract: A carbon dioxide (CO2) capture system and method for removing CO2 from an inlet gas including a first fluid stream inlet providing for the flow of a first fluid stream, such as an inlet gas containing CO2, and a second fluid stream inlet providing for the flow of a second fluid stream, such as steam, an outlet providing for the flow of a CO2 depleted stream from the CO2 capture system, an outlet providing for the flow of a CO2 stream from the CO2 capture system and a concentrator in fluid communication with the first fluid stream. The system further including a first contactor and a second contactor. Each of the first contactor and the second contactor defining therein a first fluidically-isolated, sorbent-integrated, fluid domain for flow of the first fluid stream and CO2 adsorption and a second fluidically-isolated fluid domain for flow of the second fluid stream to assist in desorption.
    Type: Application
    Filed: February 5, 2021
    Publication date: August 11, 2022
    Inventors: David Roger Moore, Vitali Victor Lissianski, Mark Daniel Doherty, Daniel Jason Erno, Anil Raj Duggal
  • Publication number: 20220251810
    Abstract: A water recovery system including a first fluid stream inlet providing for the flow of a first fluid stream, such as a humidified inlet gas, into the system and a second fluid stream inlet providing for the flow of a second fluid stream, such as a gas having a temperature greater than the humidified inlet gas, into the system. At least one contactor is in fluid communication with the first fluid stream inlet and the second fluid stream inlet.
    Type: Application
    Filed: February 5, 2021
    Publication date: August 11, 2022
    Inventors: David Roger Moore, Vitali Victor Lissianski, Albert Santo Stella, Daniel Jason Erno
  • Patent number: 11173490
    Abstract: The present disclosure relates to a sample assessment device. By way of example, the sample assessment device may include a substrate including a sample application region; an amplification region comprising a plurality of amplification reagents; a waste region comprising an entrance fluidically coupled to the amplification region and extending away from the amplification region; and a detection region spaced apart from the amplification region. The sample assessment device may also include a valve coupled to the substrate and configured to separate the amplification region from the detection region in a closed configuration, wherein the amplification region and the valve are positioned on the sample assessment device between the sample application region and the detection region and wherein the sample assessment device is configured to permit lateral flow from the amplification region to the detection region when the valve is in an open configuration.
    Type: Grant
    Filed: July 16, 2018
    Date of Patent: November 16, 2021
    Assignees: University of Washington, Global Life Sciences Solutions Operations UK Ltd.
    Inventors: David Roger Moore, Matthew Jeremiah Misner, Andrew Arthur Paul Burns, Joshua Bishop, Lisa K. Lafleur, Maxwell Wheeler
  • Patent number: 10983119
    Abstract: A rapid diagnostic testing device for testing of a biological sample is provided. The device comprises a channeled construct, at least one lateral flow unit, and a cassette housing. The channeled construct is configured to receive a biological sample to form at least partially purified biological sample. The lateral flow unit is at least partially disposed in the cassette housing. The lateral flow unit comprises: a sample receiving zone, a conjugate zone and a detection zone. The sample receiving zone is operatively coupled to the channeled construct for receiving the partially purified biological sample comprising at least one analyte. The conjugate zone comprising a conjugate particle to bind the analyte is disposed adjacent to the first side of the sample receiving zone. The detection zone is disposed adjacent to the second side of the sample receiving zone and comprises at least one binding agent for detecting the analyte.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: April 20, 2021
    Assignees: GENERAL ELECTRIC COMPANY, TOKITAE LLC
    Inventors: Bing Li, Matthew Jeremiah Misner, David Roger Moore, Kevin Paul Flood Nichols, David Cate, Matthew F Rosen
  • Publication number: 20210055297
    Abstract: A rapid detection method of a target biomolecule comprising an antigenic moiety is provided. The method includes providing a source biological sample comprising the target biomolecule; contacting the source biological sample to an ion-exchange medium; eluting the captured-target biomolecule from the ion-exchange medium as an eluate, and loading the eluate to a rapid diagnostic testing device comprising an antibody. The eluate comprises a concentrated form of the biomolecule in a solution having a salt concentration greater than 150 mM. A concentration of the target biomolecule in the eluate is in a range from about 2× to 25× compared to a concentration of the biomolecule in the source biological sample. The target biomolecule binds to the antibody under the salt concentration of greater than 150 mM. A device for rapid detection of target biomolecule is also provided.
    Type: Application
    Filed: November 5, 2020
    Publication date: February 25, 2021
    Inventors: Matthew Jeremiah Misner, Gregory Andrew Grossmann, Cathryn Ellen Olsen, John Richard Nelson, Brian Christopher Bales, David Roger Moore, Paul Michael Smigelski
  • Publication number: 20210055282
    Abstract: A device for rapid detection of a tuberculosis lipoarabinomannan (TB-LAM) is provided. The device includes a pre-concentrator unit for concentrating the TB-LAM comprising: an ion-exchange medium comprising one or more ligands configured to capture the TB-LAM from the source biological sample, wherein the captured-TB-LAM is eluted from the ion-exchange medium as an eluate comprising a concentrated form of TB-LAM; a cassette; a lateral flow assay unit disposed in the cassette; and an integration unit attached to the pre-concentrator unit and the cassette. The integration unit is configured to operatively couple and de-couple the pre-concentrator unit and the cassette. The pre-concentrator unit and the lateral flow assay unit disposed in the cassette are in a fluidic communication in a coupled form. The device for rapid detection of TB-LAM further comprises a dilutor unit.
    Type: Application
    Filed: November 6, 2020
    Publication date: February 25, 2021
    Inventors: Matthew Jeremiah Misner, Gregory Andrew Grossmann, Cathryn Ellen Olsen, John Richard Nelson, David Roger Moore, Paul Michael Smigelski, John Thomas Connelly, Benjamin David Grant, Bernhard Hans Weigl
  • Patent number: 10837962
    Abstract: A rapid detection method of a target biomolecule comprising an antigenic moiety is provided. The method includes providing a source biological sample comprising the target biomolecule; contacting the source biological sample to an ion-exchange medium; eluting the captured-target biomolecule from the ion-exchange medium as an eluate, and loading the eluate to a rapid diagnostic testing device comprising an antibody. The eluate comprises a concentrated form of the biomolecule in a solution having a salt concentration greater than 150 mM. A concentration of the target biomolecule in the eluate is in a range from about 2× to 25× compared to a concentration of the biomolecule in the source biological sample. The target biomolecule binds to the antibody under the salt concentration of greater than 150 mM. A device for rapid detection of target biomolecule is also provided.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: November 17, 2020
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Matthew Jeremiah Misner, Gregory Andrew Grossmann, Cathryn Ellen Olsen, John Richard Nelson, Brian Christopher Bales, David Roger Moore, Paul Michael Smigelski, Jr.
  • Patent number: 10830760
    Abstract: A device for rapid detection of a tuberculosis lipoarabinomannan (TB-LAM) is provided. The device includes a pre-concentrator unit for concentrating the TB-LAM comprising: an ion-exchange medium comprising one or more ligands configured to capture the TB-LAM from the source biological sample, wherein the captured-TB-LAM is eluted from the ion-exchange medium as an eluate comprising a concentrated form of TB-LAM; a cassette; a lateral flow assay unit disposed in the cassette; and an integration unit attached to the pre-concentrator unit and the cassette. The integration unit is configured to operatively couple and de-couple the pre-concentrator unit and the cassette. The pre-concentrator unit and the lateral flow assay unit disposed in the cassette are in a fluidic communication in a coupled form. The device for rapid detection of TB-LAM further comprises a dilutor unit.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: November 10, 2020
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Matthew Jeremiah Misner, Gregory Andrew Grossmann, Cathryn Ellen Olsen, John Richard Nelson, David Roger Moore, Paul Michael Smigelski, Jr., John Thomas Connelly, Benjamin David Grant, Bernhard Hans Weigl
  • Patent number: 10518227
    Abstract: A membrane including a block copolymer is presented. The block copolymer includes at least one block A including structural units having a formula (I), and at least one block B including structural units having a formula (II). A hollow-fiber membrane for hemodialysis or hemofiltration, and associated block copolymer are also presented.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: December 31, 2019
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Patrick Joseph McCloskey, Julia Lam Lee, David Roger Moore, Cathryn Ellen Olsen, Matthew Jeremiah Misner, Louisa Ruth Carr, Hongyi Zhou
  • Patent number: 10472620
    Abstract: A method is provided herein, the method includes: applying a sample comprising target nucleic acids to a sample application zone of a substrate; and flowing a nucleic acid amplification reaction mixture across a length of the substrate through the sample application zone to amplify the target nucleic acid forming a nucleic acid amplification product; wherein the target nucleic acid having a first molecular weight is substantially immobilized at the sample application zone and wherein the amplification product having a second molecular weight migrates away from the sample application zone. An associated device is also provided.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: November 12, 2019
    Assignee: General Electric Company
    Inventors: John Richard Nelson, David Roger Moore, Robert Scott Duthie, Matthew Jeremiah Misner, Gregory Andrew Grossmann, Elizabeth Marie Dees, Patrick McCoy Spooner, Erik Leeming Kvam, Andrew Arthur Paul Burns, Vicki Herzl Watkins
  • Publication number: 20190187126
    Abstract: A device for rapid detection of a tuberculosis lipoarabinomannan (TB-LAM) is provided. The device includes a pre-concentrator unit for concentrating the TB-LAM comprising: an ion-exchange medium comprising one or more ligands configured to capture the TB-LAM from the source biological sample, wherein the captured-TB-LAM is eluted from the ion-exchange medium as an eluate comprising a concentrated form of TB-LAM; a cassette; a lateral flow assay unit disposed in the cassette; and an integration unit attached to the pre-concentrator unit and the cassette. The integration unit is configured to operatively couple and de-couple the pre-concentrator unit and the cassette. The pre-concentrator unit and the lateral flow assay unit disposed in the cassette are in a fluidic communication in a coupled form. The device for rapid detection of TB-LAM further comprises a dilutor unit.
    Type: Application
    Filed: December 20, 2017
    Publication date: June 20, 2019
    Inventors: Matthew Jeremiah MISNER, Gregory Andrew GROSSMANN, Cathryn Ellen OLSEN, John Richard NELSON, David Roger MOORE, Paul Michael SMIGELSKI, JR., John Thomas CONNELLY, Benjamin David GRANT, Bernhard Hans WEIGL
  • Publication number: 20190187142
    Abstract: A rapid detection method of a target biomolecule comprising an antigenic moiety is provided. The method includes providing a source biological sample comprising the target biomolecule; contacting the source biological sample to an ion-exchange medium; eluting the captured-target biomolecule from the ion-exchange medium as an eluate, and loading the eluate to a rapid diagnostic testing device comprising an antibody. The eluate comprises a concentrated form of the biomolecule in a solution having a salt concentration greater than 150 mM. A concentration of the target biomolecule in the eluate is in a range from about 2× to 25× compared to a concentration of the biomolecule in the source biological sample. The target biomolecule binds to the antibody under the salt concentration of greater than 150 mM. A device for rapid detection of target biomolecule is also provided.
    Type: Application
    Filed: December 20, 2017
    Publication date: June 20, 2019
    Inventors: Matthew Jeremiah Misner, Gregory Andrew Grossmann, Cathryn Ellen Olsen, John Richard Nelson, Brian Christopher Bales, David Roger Moore, Paul Michael Smigelski, JR.
  • Publication number: 20190153517
    Abstract: An electrospinning approach is disclosed for generating a dissolvable formulation of a reagent of interest in a nanoscale fiber medium. In one embodiment, the nanoscale fibers can incorporate and stabilize biological agents of interest, such as for storage at room temperature for extended periods. In one implementation, the fibers can be produced in a continuous manner and dissolve rapidly.
    Type: Application
    Filed: January 29, 2019
    Publication date: May 23, 2019
    Inventors: Bing Li, David Roger Moore, William Christopher Alberts, John Richard Nelson