Patents by Inventor David Rolf

David Rolf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140141048
    Abstract: According to one aspect of the disclosure, medical devices are provided which have a negatively charged surface and a lubricous hydrophilic coating comprising a sulf(on)ated species disposed on the negatively charged surface. In various embodiments, the sulf(on)ated species is ionically crosslinked with itself and with the negatively charged species by a multivalent cationic species. In other aspects, medical devices are provided which have a polymeric surface and a lubricous hydrophilic layer comprising a covalently crosslinked sulf(on)ated species disposed on the surface. Still other aspects of the invention pertain to methods of forming such devices and methods of using such devices.
    Type: Application
    Filed: November 20, 2013
    Publication date: May 22, 2014
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: David Rolf, Steven L Kangas
  • Patent number: 8475844
    Abstract: Polymers of fluorinated monomers and acrylate and alkyl acrylates are disclosed which demonstrate improved performance as coatings for implantable devices. Such coatings may, for example, be used to release a bioactive agent from the medical device. One specific application lies in drug-eluting coatings for stents.
    Type: Grant
    Filed: April 16, 2009
    Date of Patent: July 2, 2013
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Gordon Kocur, David Rolf, James Lasch, Kasyap Seethamraju
  • Publication number: 20120232582
    Abstract: The disclosure pertains to a vascular closure plug having a reinforced proximal end and methods of use therefor. The reinforcement may comprise a proximal force distributing member and a plurality of plug restraining members thereby tending to limit tearing or spreading of at least the proximal end of the vascular closure plug. In some embodiments, the reinforcement may also comprise a distal force distributing member and a plurality of plug restraining members, a circumferential collar, and/or a supplemental force distributing member.
    Type: Application
    Filed: March 9, 2012
    Publication date: September 13, 2012
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Kristopher Vietmeier, Scott Schewe, David Rolf
  • Publication number: 20090264539
    Abstract: Polymers of fluorinated monomers and acrylate and alkyl acrylates are disclosed which demonstrate improved performance as coatings for implantable devices. Such coatings may, for example, be used to release a bioactive agent from the medical device. One specific application lies in drug-eluting coatings for stents.
    Type: Application
    Filed: April 16, 2009
    Publication date: October 22, 2009
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Gordon Kocur, David Rolf, James Lasch, Kasyap Seethamraju
  • Patent number: 7288265
    Abstract: An adhesive patch is provided wherein the patch includes a porous backing having a front side and a back side. The patch also includes a therapeutic formulation located on the front side of the backing. The backing includes a flexible sheet of water insoluble porous material. The therapeutic formulation includes a combination of a antiviral agent useful for treating a viral infection in a mammal (e.g., human), a medicament that relieves topical discomfort, an adhesive, and a solvent. The solvent can preferably include a fragrance.
    Type: Grant
    Filed: January 8, 2003
    Date of Patent: October 30, 2007
    Assignee: LecTec Corporation
    Inventor: David Rolf
  • Publication number: 20070026056
    Abstract: An adhesive patch is provided wherein the patch includes a porous backing having a front side and a back side. The patch also includes a therapeutic formulation located on the front side of the backing. The backing includes a flexible sheet of water insoluble porous material. The therapeutic formulation includes a combination of a antiviral agent useful for treating a viral infection in a mammal (e.g., human), a medicament that relieves topical discomfort, an adhesive, and a solvent. The solvent can preferably include a fragrance.
    Type: Application
    Filed: September 26, 2006
    Publication date: February 1, 2007
    Inventor: DAVID ROLF
  • Publication number: 20060165747
    Abstract: An activator comprising a biocompatible base and a known fungicide in the form of an acid salt are mixed together by the user shortly before being applied to the infection so as to react them chemically to produce the free base of the fungicide thereby rendering the composition capable of penetrating throughout the infected tissue. The free base form has been found to be much more lethal to the fungal infection, particularly in the treatment of onychomycosis. The activator is formulated to be mixed within a few days of or just before application with the fungicide, e.g., terbinafine hydrochloride (an acid salt). Although the free base is subject to degradation and has a shorter shelf life, it was found that mixing just prior to use eliminates problems that could be caused by degradation of an active ingredient. A preferred activator solution also contains a penetration enhancer and a tissue softener.
    Type: Application
    Filed: January 24, 2005
    Publication date: July 27, 2006
    Inventor: David Rolf
  • Patent number: 6830758
    Abstract: The present invention provides a water insoluble, protective, adhesive skin patch useful for treating or preventing psoriasis, dermatitis, and/or eczema. The adhesive patch includes a backing that is treated with a sizing agent (e.g., a fluorocarbon solution, a silicone-containing compound, or a combination thereof). The present invention also provides a method for treating or preventing at least one of psoriasis, dermatitis, and eczema in a mammal (e.g., human) and a method for exfoliating the skin surface of a mammal.
    Type: Grant
    Filed: April 2, 2001
    Date of Patent: December 14, 2004
    Assignee: Lectec Corporation
    Inventors: Jane Nichols, Teri Buseman, David Rolf, David Brandwein, Daniel M. McWhorter
  • Publication number: 20040236675
    Abstract: The present invention provides a method of credit aggregation in an arrangement including a borrower, a plurality of credit suppliers, and a credit aggregator, the method including the steps of: determining a borrower's credit requirements; assessing offers of credit from the credit suppliers to determine a suitable combination of credit offers to meet the needs of the borrower; the credit aggregator entering into at least one agreement with the borrower to provide the suitable combination of offers; the credit aggregator entering into separate agreements with each of the credit suppliers in relation to the relevant parts of each offer to supply credit to the borrower; wherein the arrangement of credit facilities are supplied by the credit suppliers to the borrower without the borrower entering into an agreement with the individual credit suppliers.
    Type: Application
    Filed: May 20, 2004
    Publication date: November 25, 2004
    Inventors: David Rolf Lynch, Andrew Gale, David Roger Eastwood
  • Publication number: 20040071757
    Abstract: The present invention provides a method for preventing a respiratory infection in a mammal at risk thereof. The method includes contacting a live respiratory pathogen at risk of entering the respiratory tract of the mammal with a therapeutically effective amount of an essential oil. The live respiratory pathogen is inactivated upon contact with the essential oil. The source of the essential oil is a patch located in the vicinity of the nasal passageway of the mammal. The present invention also provides a kit that includes the adhesive patch, a mask for placing over the nasal passageway, packaging material, and optionally instructions for using the adhesive patch and mask.
    Type: Application
    Filed: June 10, 2003
    Publication date: April 15, 2004
    Inventor: David Rolf
  • Patent number: 6620436
    Abstract: The invention provides a mixing and dispensing pouch for applying a wound dressing onto a wound. The pouch includes a pair of superimposed sheets, e.g., of plastic film, connected together at their edges. A pressure-rupturable seal is located between the super-imposed sheets and extends from one edge of the package to the other to form two compartments. The pressure-rupturable seal can be forced open manually by applying pressure on the exterior of the package with the hands so as to increase the hydrostatic pressure in a liquid, e.g., water contained in one compartment of the package causing the seal to rupture and the liquid to spurt through the ruptured seal, mixing with a dry wound dressing contained in the other compartment. If required, additional kneading of the package with the hands will mix the wound dressing for use as soon as it is expelled from the package.
    Type: Grant
    Filed: November 28, 1994
    Date of Patent: September 16, 2003
    Assignee: LecTec Corporation
    Inventor: David Rolf
  • Publication number: 20030152610
    Abstract: The present invention provides an adhesive patch. The adhesive patch includes a flexible backing having a front side and a back side and a cosmetic formulation positioned on at least a portion of the front side of the backing, in at least a portion of the front side of the backing, or on and in at least a portion of the front side of the backing. The cosmetic formulation includes a cosmetic agent; a solvent; a skin absorption enhancer; and at least one of a pressure sensitive adhesive and a polymer.
    Type: Application
    Filed: January 28, 2002
    Publication date: August 14, 2003
    Inventors: David Rolf, Teri Buseman, Dede Cooke
  • Publication number: 20030077316
    Abstract: The present invention provides a water insoluble, protective, adhesive skin patch useful for treating or preventing psoriasis, dermatitis, and/or eczema. The adhesive patch includes a backing that is treated with a sizing agent (e.g., a fluorocarbon solution, a silicone-containing compound, or a combination thereof). The present invention also provides a method for treating or preventing at least one of psoriasis, dermatitis, and eczema in a mammal (e.g., human) and a method for exfoliating the skin surface of a mammal.
    Type: Application
    Filed: April 2, 2001
    Publication date: April 24, 2003
    Inventors: Jane Nichols, Teri Buseman, David Rolf, David Brandwein, Daniel M. McWhorter
  • Publication number: 20020192273
    Abstract: The present invention provides an adhesive patch that includes a flexible backing having a front side and a back side. A therapeutic formulation is positioned on at least a portion of the front side of the backing, in at least a portion of the front side of the backing, or on and in at least a portion of the front side of the backing. The therapeutic formulation includes a vasoconstrictor, a solvent that dissolves the vasoconstrictor, and a pressure sensitive adhesive. The present invention also provides methods of medical use that employ the patch of the present invention. Such uses include, e.g.
    Type: Application
    Filed: April 10, 2002
    Publication date: December 19, 2002
    Inventors: Teri Buseman, David Rolf
  • Patent number: 6495158
    Abstract: An adhesive patch is provided wherein the patch includes a flexible backing having a front side and a back side. The patch also includes a therapeutic formulation positioned on and in at least a portion of the front side of the backing such that the therapeutic formulation is partially embedded in at least a portion of the front side of the backing. At least a portion of the backing is treated with a hydrophobic sizing agent such that the portion of the backing that is treated with the hydrophobic sizing agent has a surface energy of about 20 dynes/cm2 to about 65 dynes/cm2. The therapeutic formulation includes a topical acne drug, a solvent that dissolves the topical acne drug, and a pressure sensitive adhesive.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: December 17, 2002
    Assignee: Lec Tec Corporation
    Inventors: Teri Buseman, David Rolf, Daniel M. McWhorter
  • Patent number: 6469227
    Abstract: The present invention provides a non-occlusive adhesive skin patch. The patch includes a woven or nonwoven porous backing having a front side and a back side. The patch also includes a therapeutic formulation located on the front side of the backing. The backing includes a flexible sheet of water insoluble porous material. The therapeutic formulation includes a medicament useful for relieving topical discomfort and a pressure sensitive adhesive. The therapeutic formulation optionally includes a solvent that can effectively dissolve the medicament. The present invention also provides a method for alleviating topical discomfort. The method includes applying an adhesive skin patch of the present invention to skin inflicted with a topical disorder.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: October 22, 2002
    Assignee: LecTec Corporation
    Inventors: Dede Cooke, David Rolf
  • Patent number: 6406712
    Abstract: A solid elastic and pliable self-supporting wound dressing is formed by mixing dry hydrocolloid polymer powder with water. Preferably the dry polymer powder and water are contained in a sealed package having a temporary or manually-removable barrier so that the dry polymer and waster can be stored separately from each other while in the package. The wound dressing may be prepared by breaking or removing the barrier to allow intermixing of the polymer and water within the package so that a fluid, pourable and spreadable aqueous colloidal dispersion is initially formed within the package and which can be removed from the package and easily poured or spread onto the wound. The initially-formed dispersion then solidifies to form a solid or semi-solid elastic, pliable wound dressing containing water and hydrocolloid. The presence of water in the wound dressing provides desirable moisture during the healing process.
    Type: Grant
    Filed: October 25, 1994
    Date of Patent: June 18, 2002
    Assignee: LecTec Corporation
    Inventor: David Rolf
  • Patent number: 6361790
    Abstract: A non-occlusive medication patch to be applied to the skin includes a porous self-supporting backing layer to give the patch the required integrity and strength by acting as a supporting framework for other components, and a flexible hydrophilic pressure-sensitive adhesive reservoir comprising a natural or synthetic polymer for the sustained release of medication to be absorbed topically through the skin into the body of a patient. The reservoir has two portions: first, an external coating layer with an exposed lower skin-contacting surface that forms a pressure-sensitive bond with the skin, and second, an upper internal portion which infiltrates the porous backing and becomes solidified therein after being applied so that the reservoir and the backing are unified, enabling the backing itself to act as a storage location for the medication-containing reservoir.
    Type: Grant
    Filed: July 31, 2000
    Date of Patent: March 26, 2002
    Assignee: LecTec Corporation
    Inventors: David Rolf, Elisabeth K. Sjoblom Urmann
  • Patent number: 6096334
    Abstract: A non-occlusive medication patch to be applied to the skin includes a porous self-supporting backing layer to give the patch the required integrity and strength by acting as a supporting framework for other components, and a flexible hydrophilic pressure-sensitive adhesive reservoir comprising a natural or synthetic polymer for the sustained release of medication to be absorbed topically through the skin into the body of a patient. The reservoir has two portions: first, an external coating layer with an exposed lower skin-contacting surface that forms a pressure-sensitive bond with the skin, and second, an upper internal portion which infiltrates the porous backing and becomes solidified therein after being applied so that the reservoir and the backing are unified, enabling the backing itself to act as a storage location for the medication-containing reservoir.
    Type: Grant
    Filed: December 14, 1998
    Date of Patent: August 1, 2000
    Assignee: LecTec Corporation
    Inventors: David Rolf, Elisabeth K. Sjoblom Urmann
  • Patent number: 6096333
    Abstract: A non-occlusive medication patch to be applied to the skin includes a porous self-supporting backing layer to give the patch the required integrity and strength by acting as a supporting framework for other components, and a flexible hydrophilic pressure-sensitive adhesive reservoir comprising a natural or synthetic polymer for the sustained release of medication to be absorbed topically through the skin into the body of a patient. The reservoir has two portions: first, an external coating layer with an exposed lower skin-contacting surface that forms a pressure-sensitive bond with the skin, and second, an upper internal portion which infiltrates the porous backing and becomes solidified therein after being applied so that the reservoir and the backing are unified, enabling the backing itself to act as a storage location for the medication-containing reservoir.
    Type: Grant
    Filed: October 8, 1997
    Date of Patent: August 1, 2000
    Assignee: LecTec Corporation
    Inventors: David Rolf, Elisabeth K. Sjoblom Urmann