Patents by Inventor David ROUTENBERG

David ROUTENBERG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND KITS FOR VIRUS DETECTION
    Publication number: 20250237661
    Abstract: The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.
    Type: Application
    Filed: December 2, 2024
    Publication date: July 24, 2025
    Inventors: Jacob N. WOHLSTADTER, George SIGAL, Anu MATHEW, Anastasia AKSYUK, David ROUTENBERG, Martin STENGELIN, John KENTEN, Timothy J. BREAK, Seth B. HARKINS, Michael TSIONSKY
  • METHODS FOR ISOLATING SURFACE MARKER DISPLAYING AGENTS
    Publication number: 20250035615
    Abstract: The invention relates to method and kits for highly specific isolation of extracellular vesicles (EVs) by targeting at least two EV surface markers. The invention further relates to methods and kits for analyzing EVs and their contents.
    Type: Application
    Filed: August 1, 2024
    Publication date: January 30, 2025
    Inventor: David ROUTENBERG
  • METHODS FOR ANALYZING A SAMPLE
    Publication number: 20240409983
    Abstract: Provided herein are methods for analyzing a sample for an analyte using proximity-based extension, such as proximity extension strand displacement. Also provided are multiplexed methods for analyzing a sample using proximity-based extension. Provided herein are methods for screening for pairwise combination of binding moieties, for use in a sandwich-type assay. Also provided are compositions that find use in the present methods.
    Type: Application
    Filed: June 5, 2024
    Publication date: December 12, 2024
    Applicant: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: David ROUTENBERG, Evan GIZZIE, Alexander K. TUCKER-SCHWARTZ, George SIGAL, Khondaker RAHMAN, Deepak NANJAPPA
  • METHODS FOR ISOLATING AND ANALYZING A TARGET ANALYTE ENCAPSULATED BY A SURFACE MARKER DISPLAYING AGENT
    Publication number: 20240210399
    Abstract: Method and kits for highly specific detection and isolation of a target analyte encapsulated by a surface marker displaying agent (SMDA) are disclosed.
    Type: Application
    Filed: April 20, 2022
    Publication date: June 27, 2024
    Inventors: Pankaj OBEROI, David ROUTENBERG, Alexander TUCKER-SCHWARTZ
  • METHODS FOR ISOLATING CENTRAL NERVOUS SYSTEM SURFACE MARKER DISPLAYING AGENTS
    Publication number: 20230349920
    Abstract: The invention relates to method and kits for highly specific isolation of surface marker displaying agents from the central nervous system by targeting at least two surface markers. The invention further relates to methods and kits for analyzing surface marker displaying agents and their contents.
    Type: Application
    Filed: September 2, 2021
    Publication date: November 2, 2023
    Inventors: David ROUTENBERG, Sigal SHACHAR
  • Assay kits
    Patent number: 11525825
    Abstract: The present invention is directed to kits for improving assay specificity and performance in binding assays.
    Type: Grant
    Filed: September 9, 2019
    Date of Patent: December 13, 2022
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Anahit Aghvanyan, Eli N. Glezer, John Kenten, George Sigal, Martin Stengelin, David Routenberg
  • ASSAY METHODS
    Publication number: 20220357318
    Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.
    Type: Application
    Filed: July 21, 2022
    Publication date: November 10, 2022
    Inventors: Anahit AGHVANYAN, Eli N. GLEZER, John KENTEN, George SIGAL, Martin STENGELIN, David ROUTENBERG
  • METHODS AND KITS FOR VIRUS DETECTION
    Publication number: 20220003766
    Abstract: The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.
    Type: Application
    Filed: April 30, 2021
    Publication date: January 6, 2022
    Inventors: Jacob N. WOHLSTADTER, George SIGAL, Anu MATHEW, Anastasia AKSYUK, David ROUTENBERG, Martin STENGELIN, John KENTEN, Timothy J. BREAK, Seth B. HARKINS, Michael TSIONSKY
  • METHODS FOR ISOLATING SURFACE MARKER DISPLAYING AGENTS
    Publication number: 20210389304
    Abstract: The invention relates to method and kits for highly specific isolation of extracellular vesicles (EVs) by targeting at least two EV surface markers. The invention further relates to methods and kits for analyzing EVs and their contents.
    Type: Application
    Filed: May 17, 2019
    Publication date: December 16, 2021
    Inventor: David ROUTENBERG
  • METHODS FOR ISOLATING SURFACE MARKER DISPLAYING AGENTS
    Publication number: 20210382043
    Abstract: The invention relates to method and kits for highly specific isolation of surface marker displaying agents by targeting at least two surface markers. The invention further relates to methods and kits for analyzing surface marker displaying agents and their contents.
    Type: Application
    Filed: October 23, 2019
    Publication date: December 9, 2021
    Inventors: David ROUTENBERG, Alexander K. TUCKER-SCHWARTZ, Sigal SHACHAR
  • ASSAY METHODS
    Publication number: 20190391140
    Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.
    Type: Application
    Filed: September 9, 2019
    Publication date: December 26, 2019
    Applicant: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Anahit Aghvanyan, Eli N. Glezer, John Kenten, George Sigal, Martin Stengelin, David Routenberg
  • Assay methods
    Patent number: 10408823
    Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: September 10, 2019
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Anahit Aghvanyan, Eli N. Glezer, John Kenten, George Sigal, Martin Stengelin, David Routenberg
  • IMPROVED ASSAY METHODS
    Publication number: 20170089892
    Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.
    Type: Application
    Filed: May 15, 2015
    Publication date: March 30, 2017
    Applicant: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Anahit AGHVANYAN, Eli N. GLEZER, John KENTEN, George SIGAL, Martin STENGELIN, David ROUTENBERG