Patents by Inventor David RUSHWORTH

David RUSHWORTH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SELECTION METHODS FOR GENETICALLY-MODIFIED T CELLS
    Publication number: 20210054346
    Abstract: In some aspects, isolated transgenic cells (e.g., transgenic T cells) are provided that comprise or express a transgene and DHFRFS and/or TYMSSS. Methods for selecting transgeneic cells are also provided.
    Type: Application
    Filed: September 4, 2020
    Publication date: February 25, 2021
    Inventors: David RUSHWORTH, Laurence J.N. COOPER
  • Selection methods for genetically-modified T cells
    Patent number: 10808230
    Abstract: In some aspects, isolated transgenic cells (e.g., transgenic T cells) are provided that comprise or express a transgene and DHFRFS and/or TYMSSS. Methods for selecting transgenic cells are also provided.
    Type: Grant
    Filed: February 24, 2016
    Date of Patent: October 20, 2020
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: David Rushworth, Laurence J. N. Cooper
  • SELECTION METHODS FOR GENETICALLY-MODIFIED T CELLS
    Publication number: 20180298349
    Abstract: In some aspects, isolated transgenic cells (e.g., transgenic T cells) are provided that comprise or express a transgene and DHFRFS and/or TYMSSS. Methods for selecting transgenic cells are also provided.
    Type: Application
    Filed: February 24, 2016
    Publication date: October 18, 2018
    Inventors: David RUSHWORTH, Laurence J.N. COOPER
  • ANTI-CD19 scFv (FMC63) POLYPEPTIDE AND USES THEREOF
    Publication number: 20180265595
    Abstract: Provided are monoclonal antibodies that detect CD19 CAR-modified immune cells and CAR-modified immune cells irrespective of the tumor associated antigen they target. Methods of using these functional monoclonal antibodies include, but are not limited to, detection, quantification, activation, and selective propagation of CAR-modified immune cells.
    Type: Application
    Filed: March 5, 2018
    Publication date: September 20, 2018
    Inventors: Laurence JN COOPER, Bipulendu JENA, Sourindra MAITI, Harjeet SINGH, David RUSHWORTH
  • CHIMERIC ANTIGEN RECEPTOR-TARGETING MONOCLONAL ANTIBODIES
    Publication number: 20160096902
    Abstract: Provided are monoclonal antibodies that detect CD 19 CAR-modified immune cells and CAR-modified immune cells irrespective of the tumor associated antigen they target. Methods of using these functional monoclonal antibodies include, but are not limited to, detection, quantification, activation, and selective propagation of CAR-modified immune cells.
    Type: Application
    Filed: May 23, 2014
    Publication date: April 7, 2016
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Laurence JN COOPER, Bipulendu JENA, Harjeet SINGH, David RUSHWORTH