Patents by Inventor David S. F. Young

David S. F. Young has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7361342
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: April 22, 2008
    Assignee: Arius Research Inc.
    Inventors: David S. F. Young, Susan E. Hahn, Helen P. Findlay
  • Patent number: 7361343
    Abstract: This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMABs of the instant invention.
    Type: Grant
    Filed: March 26, 2004
    Date of Patent: April 22, 2008
    Assignee: Arius Research Inc.
    Inventors: David S. F. Young, Susan E. Hahn, Helen P. Findlay, Luis A. G. da Cruz
  • Patent number: 7348413
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: March 25, 2008
    Assignee: Arius Research Inc.
    Inventors: David S. F. Young, Susan E. Hahn, Lisa M. Cechetto
  • Patent number: 7256271
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Grant
    Filed: January 21, 2003
    Date of Patent: August 14, 2007
    Assignee: Arius Research Inc.
    Inventors: David S. F. Young, Susan E. Hahn
  • Patent number: 7256272
    Abstract: The present invention relates to a method for producing patient specific anti-cancer antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies customized for the individual patient that can be used for therapeutic and diagnostic purposes. The invention further relates to the process by which the antibodies are made and to their methods of use. The antibodies can be made specifically for one tumor derived from a particular patient and are selected on the basis of their cancer cell cytotoxicity and simultaneous lack of toxicity for non-cancerous cells.
    Type: Grant
    Filed: November 13, 2003
    Date of Patent: August 14, 2007
    Assignee: Arius Research Inc.
    Inventors: David S. F. Young, Miyoko Takahashi
  • Patent number: 7252821
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Grant
    Filed: June 23, 2003
    Date of Patent: August 7, 2007
    Assignee: Arius Research Inc.
    Inventors: David S. F. Young, Helen P. Findlay, Susan E. Hahn, Miyoko Takahashi
  • Patent number: 7247476
    Abstract: The present invention relates to a method for producing patient specific anti-cancer antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies customized for the individual patient that can be used for therapeutic and diagnostic purposes. The invention further relates to the process by which the antibodies are made and to their methods of use. The antibodies can be made specifically for one tumor derived from a particular patient and are selected on the basis of their cancer cell cytotoxicity and simultaneous lack of toxicity for non-cancerous cells. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat tumor metastases.
    Type: Grant
    Filed: September 30, 2005
    Date of Patent: July 24, 2007
    Assignee: Arius Research Inc.
    Inventors: David S. F. Young, Miyoko Takahashi
  • Patent number: 7195764
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Grant
    Filed: September 15, 2004
    Date of Patent: March 27, 2007
    Assignee: Arius Research Inc.
    Inventors: David S. F. Young, Susan E. Hahn, Helen P. Findlay
  • Patent number: 7189397
    Abstract: This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMABs of the instant invention.
    Type: Grant
    Filed: August 22, 2003
    Date of Patent: March 13, 2007
    Assignee: Arius Research Inc.
    Inventors: David S. F. Young, Susan E. Hahn, Helen P. Findlay
  • Patent number: 7189825
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: March 13, 2007
    Assignee: Arius Research Inc.
    Inventors: David S. F. Young, Susan E. Hahn, Helen P. Findlay
  • Patent number: 7186808
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: March 6, 2007
    Assignee: Arius Research Inc.
    Inventors: David S. F. Young, Susan E. Hahn, Helen P. Findlay
  • Patent number: 7175846
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Grant
    Filed: August 3, 2006
    Date of Patent: February 13, 2007
    Assignee: Arius Research Inc.
    Inventors: David S. F. Young, Susan E. Hahn, Helen P. Findlay
  • Patent number: 7009040
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Grant
    Filed: January 21, 2003
    Date of Patent: March 7, 2006
    Assignee: Arius Research, Inc.
    Inventors: David S. F. Young, Susan E. Hahn, Helen P. Findlay
  • Publication number: 20040258693
    Abstract: This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMABs of the instant invention.
    Type: Application
    Filed: March 26, 2004
    Publication date: December 23, 2004
    Inventors: David S. F. Young, Susan E. Hahn, Helen P. Findlay, Luis A. G. da Cruz
  • Publication number: 20040253653
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Application
    Filed: July 15, 2004
    Publication date: December 16, 2004
    Applicant: Arius Research, Inc.
    Inventors: David S.F. Young, Susan E. Hahn, Helen P. Findlay
  • Publication number: 20040197328
    Abstract: This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMABs of the instant invention.
    Type: Application
    Filed: March 26, 2004
    Publication date: October 7, 2004
    Inventors: David S. F. Young, Susan E. Hahn, Helen P. Findlay, Alison L. Ferry
  • Patent number: 6794494
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Grant
    Filed: April 14, 2003
    Date of Patent: September 21, 2004
    Assignee: Arius Research, Inc.
    Inventors: David S. F. Young, Susan E. Hahn
  • Publication number: 20040180002
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Application
    Filed: March 26, 2004
    Publication date: September 16, 2004
    Inventors: David S. F. Young, Susan E. Hahn, Helen P. Findlay
  • Publication number: 20040151665
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Application
    Filed: January 20, 2004
    Publication date: August 5, 2004
    Applicant: Arius Research, Inc.
    Inventors: David S. F. Young, Susan E. Hahn, Helen P. Findlay
  • Publication number: 20040141979
    Abstract: The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 22, 2004
    Applicant: Arius Research, Inc.
    Inventors: David S.F. Young, Susan E. Hahn, Helen P. Findlay