Abstract: Embodiments of devices and methods to maintain preservative concentration in a medication delivered using a medical device are provided. A barrier layer can be used to prevent migration of preservatives. A vent can be used to allow release of preservatives prior to delivery to the patient. An absorbent element can be used to maintain preservative concentration at a desired level. A filter can be used to capture particulates from the medication prior to delivery to a patient.

Abstract: Embodiments of systems and methods for delivering a medicament using a pump are provided. The methods comprise inserting a first cannula into subcutaneous tissue. Medicament is delivered from a medicament pump through the first cannula according to a dosing protocol. The first cannula can removed after a period of time and a second cannula can be inserted. The method comprises modifying the dosing protocol based upon a cannula change indicator, the modifying comprising performing neural network calculations utilizing previously calculated error data, resulting in a modified dosing protocol. Medicament is delivered from the medicament pump through the second cannula according to the modified dosing protocol.

Abstract: A system for delivering fluid to a user transcutaneously includes a subcutaneous infusion cannula base assembly, a cannula inserter assembly and a fluid connection assembly. The subcutaneous infusion cannula base assembly is configured to be located on the user's skin. The cannula inserter assembly is coupled to the cannula base assembly and is configured to drive an infusion cannula through the user's skin in a nominally helical trajectory. The fluid connection assembly is configured to fluidically connect the cannula base assembly to a source of delivery fluid. Cannula and stylet assemblies configured for helical or non-helical insertion are also disclosed.

Abstract: Embodiments of devices and methods to maintain preservative concentration in a medication delivered using a medical device are provided. A barrier layer can be used to prevent migration of preservatives. A vent can be used to allow release of preservatives prior to delivery to the patient. An absorbent element can be used to maintain preservative concentration at a desired level. A filter can be used to capture particulates from the medication prior to delivery to a patient.

Abstract: A system for delivering fluid to a user transcutaneously includes a subcutaneous infusion cannula base assembly, a cannula inserter assembly and a fluid connection assembly. The subcutaneous infusion cannula base assembly is configured to be located on the user's skin. The cannula inserter assembly is coupled to the cannula base assembly and is configured to drive an infusion cannula through the user's skin in a nominally helical trajectory. The fluid connection assembly is configured to fluidically connect the cannula base assembly to a source of delivery fluid. Cannula and stylet assemblies configured for helical or non-helical insertion are also disclosed.

Abstract: A system for delivering fluid to a user transcutaneously includes a subcutaneous infusion cannula base assembly, a cannula inserter assembly and a fluid connection assembly. The subcutaneous infusion cannula base assembly is configured to be located on the user's skin. The cannula inserter assembly is coupled to the cannula base assembly and is configured to drive an infusion cannula through the user's skin in a nominally helical trajectory. The fluid connection assembly is configured to fluidically connect the cannula base assembly to a source of delivery fluid. Cannula and stylet assemblies configured for helical or non-helical insertion are also disclosed.

Abstract: A system for delivering fluid to a user transcutaneously includes a subcutaneous infusion cannula base assembly, a cannula inserter assembly and a fluid connection assembly. The subcutaneous infusion cannula base assembly is configured to be located on the user's skin. The cannula inserter assembly is coupled to the cannula base assembly and is configured to drive an infusion cannula through the user's skin in a nominally helical trajectory. The fluid connection assembly is configured to fluidically connect the cannula base assembly to a source of delivery fluid. Cannula and stylet assemblies configured for helical or non-helical insertion are also disclosed.

Abstract: A system for delivering fluid to a user transcutaneously includes a subcutaneous infusion cannula base assembly, a cannula inserter assembly and a fluid connection assembly. The subcutaneous infusion cannula base assembly is configured to be located on the user's skin. The cannula inserter assembly is coupled to the cannula base assembly and is configured to drive an infusion cannula through the user's skin in a nominally helical trajectory. The fluid connection assembly is configured to fluidically connect the cannula base assembly to a source of delivery fluid. Cannula and stylet assemblies configured for helical or non-helical insertion are also disclosed.

Abstract: A semiconductor integrated circuit includes a hardware mechanism arranged to ensure that associations between instructions and data are enforced so that a processor cannot execute an instruction that is not authorized. A Command Filter Matrix stores entries comprising instructions and associated data memory ranges. A hardware arrangement denies command execution if the CPU attempts to make a data fetch from an instruction that is outside the range associated with data in the Command Filter Matrix. The Command Filter Matrix may be implemented in a Field Programmable Gate Array such that the memory cell content is pre-programmed with entrusted code by a separate trusted hardware source. In this way, an operating system may function normally but only execute trusted instructions, commands and memory operations. The Command Filter Matrix also contains external write-only capability to enable external monitoring of performance.

Abstract: A semiconductor integrated circuit includes a hardware mechanism arranged to ensure that associations between instructions and data are enforced so that a processor cannot execute an instruction that is not authorized. A Command Filter Matrix stores entries comprising instructions and associated data memory ranges. A hardware arrangement denies command execution if the CPU attempts to make a data fetch from an instruction that is outside the range associated with data in the Command Filter Matrix. The Command Filter Matrix may be implemented in a Field Programmable Gate Array such that the memory cell content is pre-programmed with entrusted code by a separate trusted hardware source. In this way, an operating system may function normally but only execute trusted instructions, commands and memory operations. The Command Filter Matrix also contains external write-only capability to enable external monitoring of performance.

Abstract: A compensating drug delivery system for delivery of medicaments to animals is described. A drug-containing reservoir is connected to a needle array through a flow tube. Medicament delivery to the animal through this flow tube is regulated by the combined action of a metering means and a valving means, and inaccuracies in delivery rate are compensated. The metering means and the valving means are microprocessor controlled to insure that the medication administered is according to a pre-established protocol.