Patents by Inventor David S. Lake

David S. Lake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8952693
    Abstract: A method for calculating a mechanical property of a material using a magnetic resonance imaging (“MRI”) system is provided. The method is particularly robust to image data having low signal-to-noise ratio (“SNR”). An MRI system is used to acquire magnetic resonance elastography (“MRE”) data from a subject containing the material. Exemplary materials include lung tissue. Images are reconstructed from the MRE data and used to produce a wave image from which a spatial frequency spectrum is produced. A principal frequency of the spatial frequency spectrum is produced and used to calculate a mechanical property of the material. For example, shear stiffness may be calculated.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: February 10, 2015
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David S Lake, Kiaran P McGee, Armando Manduca, Yogesh K Mariappan, Richard L Ehman
  • Patent number: 8653816
    Abstract: Systems, methods and articles of manufacture are disclosed for compensating for motion of a subject during an MRI scan of the subject. k-space data may be received from the MRI scan of the subject. Motion information may be received for the subject. Based on the received motion information, a translational motion of the subject may be determined between a first point in time and a second point in time. A search space for motion correction may be reduced using the determined change and an error margin of the capturing technique. A motion-compensated, graphical image of the subject may be generated using the reduced search space.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: February 18, 2014
    Assignee: International Business Machines Corporation
    Inventors: David S. Lake, Armando Manduca, Jeffrey S. McAllister, Nelson Ramirez
  • Patent number: 8498689
    Abstract: Systems, methods and articles of manufacture are disclosed for capturing motion information in a magnetic resonance imaging (MRI) environment. A light sink in the MRI environment may detect light emitted from a plurality of light sources. Each of the plurality of light sources may emit light of a different frequency. Further, each of the plurality of light sources may be located at a different spatial position in the MRI environment. The detected light may be analyzed. A change in spatial position of the light sink may be computed based on the analysis.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: July 30, 2013
    Assignee: International Business Machines Corporation
    Inventors: David S. Lake, Armando Manduca, Jeffrey S. McAllister, Nelson Ramirez
  • Patent number: 8396267
    Abstract: Systems, methods and articles of manufacture are disclosed for compensating for motion of a subject during an MRI scan of the subject. k-space data may be received from the MRI scan of the subject. A first graphical image may be generated from a first set of data elements from the k-space data. Similarly, a second graphical image may be generated from a second set of data elements from the k-space data. An offset in pixels may be determined by which to translate the second graphical image from the first graphical image to compensate for the motion. The k-space data may be modified at a sub-pixel offset relative to the determined offset. A motion-compensated graphical image of the subject may be generated from the modified k-space data. Doing so reduces the search space evaluated to sharpen images generated from the k-space data.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: March 12, 2013
    Assignee: International Business Machines Corporation
    Inventors: David S. Lake, Armando Manduca, Jeffrey S. McAllister, Timothy J. Mullins, Nelson Ramirez
  • Publication number: 20120268128
    Abstract: A method for calculating a mechanical property of a material using a magnetic resonance imaging (“MRI”) system is provided. The method is particularly robust to image data having low signal-to-noise ratio (“SNR”). An MRI system is used to acquire magnetic resonance elastography (“MRE”) data from a subject containing the material. Exemplary materials include lung tissue. Images are reconstructed from the MRE data and used to produce a wave image from which a spatial frequency spectrum is produced. A principal frequency of the spatial frequency spectrum is produced and used to calculate a mechanical property of the material. For example, shear stiffness may be calculated.
    Type: Application
    Filed: April 23, 2012
    Publication date: October 25, 2012
    Inventors: David S. Lake, Kiaran P. McGee, Armando Manduca, Yogesh K. Mariappan, Richard L. Ehman
  • Publication number: 20110101978
    Abstract: Systems, methods and articles of manufacture are disclosed for compensating for motion of a subject during an MRI scan of the subject. k-space data may be received from the MRI scan of the subject. Motion information may be received for the subject. Based on the received motion information, a translational motion of the subject may be determined between a first point in time and a second point in time. A search space for motion correction may be reduced using the determined change and an error margin of the capturing technique. A motion-compensated, graphical image of the subject may be generated using the reduced search space.
    Type: Application
    Filed: November 4, 2009
    Publication date: May 5, 2011
    Applicants: INTERNATIONAL BUSINESS MACHINES CORPORATION, MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: David S. Lake, Armando Manduca, Jeffrey S. McAllister, Nelson Ramirez
  • Publication number: 20110105883
    Abstract: Systems, methods and articles of manufacture are disclosed for capturing motion information in a magnetic resonance imaging (MRI) environment. A light sink in the MRI environment may detect light emitted from a plurality of light sources. Each of the plurality of light sources may emit light of a different frequency. Further, each of the plurality of light sources may be located at a different spatial position in the MRI environment. The detected light may be analyzed. A change in spatial position of the light sink may be computed based on the analysis.
    Type: Application
    Filed: November 4, 2009
    Publication date: May 5, 2011
    Applicants: INTERNATIONAL BUSINESS MACHINES CORPORATION, MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: David S. Lake, Armando Manduca, Jeffrey S. McAllister, Nelson Ramirez
  • Publication number: 20110105882
    Abstract: Systems, methods and articles of manufacture are disclosed for compensating for motion of a subject during an MRI scan of the subject. k-space data may be received from the MRI scan of the subject. A first graphical image may be generated from a first set of data elements from the k-space data. Similarly, a second graphical image may be generated from a second set of data elements from the k-space data. An offset in pixels may be determined by which to translate the second graphical image from the first graphical image to compensate for the motion. The k-space data may be modified at a sub-pixel offset relative to the determined offset. A motion-compensated graphical image of the subject may be generated from the modified k-space data. Doing so reduces the search space evaluated to sharpen images generated from the k-space data.
    Type: Application
    Filed: November 4, 2009
    Publication date: May 5, 2011
    Applicants: INTERNATIONAL BUSINESS MACHINES CORPORATION, MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: David S. Lake, Armando Manduca, Jeffrey S. McAllister, Timothy J. Mullins, Nelson Ramirez