Abstract: A tissue penetrating cannula comprises a tube having a sharp end formed by a first cut surface defining an acute angle to the longitudinal axis of the tube and forming a generally oval tube edge defining a similar acute angle to the longitudinal axis. A second cut surface is defined along a right hand forward portion of the oval tube edge, and a third cut surface is defined along a left hand forward portion of the oval tube edge. A second and third cut surfaces define between them a forward cutting surface in the tube edge. A fourth cut surface at the point intersects the second and third cut surfaces to cause the cutting surface to be spaced inwardly of the tube outer wall. Fifth and sixth cut surfaces are provided to respectively flatten the tube edge between the first and second surfaces and the first and third surfaces.

Abstract: A combined arterial-venous blood flow set comprises connected lengths of flexible tubing for receiving blood from a patient, for conveying the blood to a blood processing device such as a dialyzer or an LDL filter, and for returning the blood to the patient. An optional first bubble trap chamber is connected in series flow between two of the lengths of tubing at a flow position downstream from the patient and upstream from the blood processing device. A second bubble trap chamber is connected in series flow between two of the lengths of tubing at a flow position downstream from the blood processing device and upstream from the patient. A first portion of the tubing which is in a flow position upstream from the blood processing device extends by the second bubble trap chamber, and is physically, laterally connected to it without direct flow connection. This helps to stabilize the positioning of components of the flow set and to reduce confusion in set-up and priming.

Abstract: A molded squeeze clamp for tubing which comprises a strip of plastic having first and second ends, the strip being bent back on itself so that the ends are adjacent to each other in the manner of a Halkey-Roberts clamp. The first strip end defines a first latch, for engagement and releasable locking with the second end, and the second end defines a second latch for locking with the first latch. The first end also defines a first projection extending towards the second end to reduce or eliminate a gap between the first and second ends when the clamp is in its unstressed, as-molded, open configuration. The second end defines a second projection to facilitate manual opening of the clamp, the second projection extending in substantially longitudinal relation to the axis of tubing carried in the squeeze clamp.

Abstract: A blood processing system (e.g. a dialysis system) having a blood processing unit (e.g. a hemodialyzer) and tubular arterial and venous blood flow sets (10, 14) may be primed by temporarily connecting together the ends of the sets and then passing priming solution in a first flow direction (44) that is retrograde to the normal flow of blood. This causes the priming solution to enter an in-line chamber (64) carried by one of the sets. At the same time, air is removed through a port (62). Preferably, the chamber includes a filter (65). In another step, priming solution is passed through the sets in a second flow direction (42), opposite the first flow direction, while continuing to remove air through the port. Preferably, the solution is passed in the first flow direction by gravity and in the second flow direction with a pump (26a). The solution can also be passed in both directions simultaneously.

Abstract: A tubular set is provided for the extracorporeal treatment of blood, for example hemodialysis. The set comprises a patient arterial line and a patient venous line, each line having a patient connector at one end thereof. Each patient line connects at its other end to a reversing flow valve. The valve also connects to respective first ends of a blood processing unit arterial line and a blood processing unit venous line. Each of the unit lines carry a connector at ends opposed to the first ends for connection respectively to arterial and venous ports of a blood processing device, typically a dialyzer. The reversing flow valve has a first position that respectively connects the patient and unit arterial lines with the patient and unit venous lines. The reversing flow valve has a second position that connects the patient arterial line with the unit venous line, and the unit arterial line with the patient venous line.

Abstract: A flow through bubble trap for fluid flow lines comprises a chamber-defining wall and a flow inlet/outlet tube at least substantially extending through the chamber and open at opposed tube ends to respectively define an inlet and an outlet of the bubble trap. The tube defines a flow inlet port and a flow outlet port within the chamber interior. A flow blocking partition closes the bore of the tube between the flow inlet and outlet ports. Additionally, the chamber defining wall carries a retaining-sealing member for removable, sealing connection with a tube connector of a fluid flow line. The retaining-sealing member is free of fluid flow connection with the interior of the chamber defined by the wall, and thus serves as a seal for connectors on tube ends of a set carrying the bubble trap. Also, the chamber defining wall has a bottom wall that defines a third port.

Abstract: Blood lines for hemodialysis and other blood handling procedures may be reused by placing connectors intermediately along the length of the blood lines so that the lines can be disconnected to separate out reusable portions thereof. Specifically, the bulk of the blood lines used may comprise branchless lengths of tubing which are easily reusable, and may be cleaned and stored along with a dialyzer or similar device by connection to a conventional reuse machine. Also, the connectors on the blood lines which are reused may have first and second sealing surfaces. The first sealing surfaces are used in the connections made to form the blood line in its normal form for use. Then, during cleaning and sterilization for reuse, the reusable connectors can connect first and second lengths of blood lines together making use of a second sealing surface, in which the first sealing surfaces are exposed to cleaning/storing solution to cause cleaning and antibacterial action on the first sealing surfaces.

Abstract: An extracorporeal, flow-through bubble trap for blood lines having improved capabilities at high flow rates and with smaller bubbles. The bubble trap comprises a chamber-defining wall, plus a blood inlet and a blood outlet, each extending through the wall to communicate with the interior of the chamber. The blood outlet connects with the chamber interior adjacent the bottom thereof. The chamber interior has a height that is less than 1.6 times the longest horizontal dimension of the chamber interior. As a result of this, blood flow in the bubble trap chamber is substantially horizontal.

Abstract: A squeeze clamp for flexible tubing comprises a strip of plastic which is bent back on itself so that the ends are adjacent to each other. The strip defines a pair of spaced apertures to permit a flexible tube to extend through and be carried by the clamp. First and second latches at the respective ends can hold the clamp in a closed position, or it can spring outwardly into an open position. The apertures extend laterally through a first side edge of the strip, with the apertures thus being each located next to a narrow strip portion connected to wider strip portions on either side of the narrow strip portion. At least one of the narrow strip portions extends laterally outwardly beyond the side edge of the rest of the plastic strip for strengthening of the narrow strip portion, to reduce problems of involuntary twisting or torsion as the clamp is closed.

Abstract: A molded squeeze clamp for tubing which comprises a strip of plastic having first and second ends, the strip being bent back on itself so that the ends are adjacent to each other in the manner of a Halkey-Roberts clamp. The first strip end defines a first latch, for engagement and releasable locking with the second end, and the second end defines a second latch for locking with the first latch. The first end also defines a first projection extending towards the second end to reduce or eliminate a gap between the first and second ends when the clamp is in its unstressed, as-molded, open configuration. The second end defines a second projection to facilitate manual opening of the clamp, the second projection extending in substantially longitudinal relation to the axis of tubing carried in the squeeze clamp.

Abstract: A combined arterial-venous blood flow set comprises connected lengths of flexible tubing for receiving blood from a patient, for conveying the blood to a blood processing device such as a dialyzer or an LDL filter, and for returning the blood to the patient. An optional first bubble trap chamber is connected in series flow between two of the lengths of tubing at a flow position downstream from the patient and upstream from the blood processing device. A second bubble trap chamber is connected in series flow between two of the lengths of tubing at a flow position downstream from the blood processing device and upstream from the patient. A first portion of the tubing which is in a flow position upstream from the blood processing device extends by the second bubble trap chamber, and is physically, laterally connected to it without direct flow connection. This helps to stabilize the positioning of components of the flow set and to reduce confusion in set-up and priming.

Abstract: A flow through bubble trap comprises a chamber-defining wall having a flow inlet/outlet tube extending through the chamber and open at opposed tube ends. The tube has its bore closed with a partition, with ports in the side wall communicating with the chamber interior on opposite sides of the partition and adjacent to the bottom wall of the chamber.

Abstract: A flow through bubble trap for fluid flow lines comprises a chamber having a substantially flat, lateral side, a first port tube, and a second, opposed port tube. A flow directing baffle system is positioned in the chamber to direct incoming fluid from one of the port tubes into a first, lateral flow direction to allow substantially horizontal fluid flow circulation in the chamber. Fluid flow from the circulating fluid in the chamber enters into the other of the port tubes in a lateral flow direction that is generally the same as the first lateral flow direction, while the baffle system prevents direct flow between the first and second port tubes. The chamber is adaptable to fit with a large variety of conventional dialysis machines and the like, having multi-purpose supplemental access ports, for a simplification of the number of codes necessary for product distribution.

Abstract: A medical fluid set comprises tubing sections interconnected with at least one tubing connector component which connects the tubing sections together to form the set. The set further comprises external connectors carried on ends of at least some tubing sections of the set. At least one of the tubing connector components or external connectors carry, as an integral part thereof, a retaining-sealing member for removable, sealing connection with at least one of the external connectors. The retaining-sealing member is free of fluid flow connection with the set flow path. Thus, separate or tethered closure caps for external connectors can be dispensed with.

Abstract: A flow through bubble trap for fluid flow lines comprises a chamber having a substantially flat, lateral side, a first port tube, and a second, opposed port tube. A flow directing baffle system is positioned in the chamber to direct incoming fluid from one of the port tubes into a first, lateral flow direction to allow substantially horizontal fluid flow circulation in the chamber. Fluid flow from the circulating fluid in the chamber enters into the other of the port tubes in a lateral flow direction that is generally the same as the first lateral flow direction, while the baffle system prevents direct flow between the first and second port tubes. The chamber is adaptable to fit with a large variety of conventional dialysis machines and the like, having multi-purpose supplemental access ports, for a simplification of the number of codes necessary for product distribution.

Abstract: A needle protector sheath comprises a body having a top wall, sidewalls and open ends. A slot is formed in each sidewall to slidingly receive a needle wing extending through each of the slots. Typically the slots extend through one end of the protector sheath. The protector sheath also defines an open, bottom aperture extending from end to end of the body, to permit the sheath to be laterally applied to tubing connected to a winged needle and to be advanced to a position where the needle tip is recessed in the sheath and the needle wings extend through the slots. In another embodiment an elongated anchor member may extend forwardly from the body to be manually pressed to retain the protector sheath as the needle is being withdrawn from the skin of a patient. The anchor member may have an outer end portion that bends away from the patient in position of use. Also, a novel sheath design and slot arrangement is disclosed.

Abstract: A blood processing system such as a dialysis system may be primed by passing priming solution in a first direction of flow through at least one of the sets, to cause the priming solution to enter an in-line chamber carried by the one set in a flow direction that is retrograde to the normal direction of blood flow through the chamber. Preferably, the in-line chamber carries a filter. Simultaneously, one removes air from the one set through a port. In another, preferably simultaneous step of the process, one passes priming solution in the second, reverse direction of flow to the first direction, through the blood processing unit and connected sets for continuing to remove air from the system through the port, to complete priming of the system.

Abstract: A female tube connector defining a tapered socket having an open, inner end communicating with the lumen of a tube, and a sealing cap proportioned to close the connector and to seal the tapered socket. The sealing cap comprises a cap body and a tapered projection proportioned to sealingly fit within the tapered socket. The projection is carried by the cap body and extends beyond the cap body by a distance to permit the projection to substantially completely occupy the whole length of the tapered socket when the cap is closing the female connector. The projection has an outer surface that carries an antiseptic material, so that upon such closure the interior of the tube connector can be sterilized between uses.

Abstract: A hemodialysis system includes the following: a dialysate handling unit for providing dialysate to the patient. This unit includes a hemodialysis solution pump and apparatus for monitoring hemodialysis solution safety such as a conductivity tester. Additionally a solution heater and appropriate conventional controls can be provided, as well as a proportioning system, an ultrafiltration measuring unit, and other known apparatus for handling dialysis solution. A blood handling unit is also provided, which includes a membrane dialyzer and holder, a blood pump, blood flow tubing and safety equipment for monitoring blood flow as it is pumped through the arterial/venous blood conduit set tubing from the patient, through the membrane dialyzer, and back to the patient. A first conduit is present for conveying fresh dialysate from the dialysate handling unit to the blood handling unit (or directly to the membrane dialyzer).

Abstract: An extracorporeal blood set may be primed with physiological solution for use in a blood transporting process such as hemodialysis. The set comprises tubing having a patient connector on an end thereof, and a first branch tube in connection with a source of the solution. The branch tube connects with the set between the ends of the set. The branch tube also connects with further branch tubing, having a second connector which is capable of sealing connection with the patient connector. The method comprises the steps of connecting the patient connector and the second connector to form a closed loop of tubing. One then passes the solution from the source in flow through the first branch tube and further branch tubing to fill them and the set tubing with the solution. One then disconnects the patient connector for subsequent connection with the vascular system of a patient.