Abstract: This disclosure relates to Cas9-nucleic acid complexes and uses related thereto. In certain embodiments, the disclosure contemplates transgenic plants and animals genetically engineered to express Cas9-nucleic acid complexes disclosed herein. In certain embodiments, the disclosure relates to methods of treating or preventing, diseases, conditions, cancer, viral infections or other pathogenic infection using vectors configured to express a Cas9-nucleic acid complex disclosed herein.

Abstract: This disclosure relates to Cas9-nucleic acid complexes and uses related thereto. In certain embodiments, the disclosure contemplates transgenic plants and animals genetically engineered to express Cas9-nucleic acid complexes disclosed herein. In certain embodiments, the disclosure relates to methods of treating or preventing, diseases, conditions, cancer, viral infections or other pathogenic infection using vectors configured to express a Cas9-nucleic acid complex disclosed herein.

Abstract: This disclosure relates to Cas9-nucleic acid complexes and uses related thereto. In certain embodiments, the disclosure contemplates transgenic plants and animals genetically engineered to express Cas9-nucleic acid complexes disclosed herein. In certain embodiments, the disclosure relates to methods of treating or preventing, diseases, conditions, cancer, viral infections or other pathogenic infection using vectors configured to express a Cas9-nucleic acid complex disclosed herein.

Abstract: This disclosure relates to Cas9-nucleic acid complexes and uses related thereto. In certain embodiments, the disclosure contemplates transgenic plants and animals genetically engineered to express Cas9-nucleic acid complexes disclosed herein. In certain embodiments, the disclosure relates to methods of treating or preventing, diseases, conditions, cancer, viral infections or other pathogenic infection using vectors configured to express a Cas9-nucleic acid complex disclosed herein.

Abstract: The present invention relates to photoconductive elements having an electrically conductive support, an electrical barrier layer and, disposed over the conductive layer, a charge generation layer capable of generating positive charge carriers when exposed to actinic radiation. The electrical barrier layer, which restrains injection of positive charge carriers from the conductive support, comprises a crosslinkable condensation polymer having as a repeating unit a planar, electron-deficient, tetracarbonylbisimide group and optionally a crosslinker.

Abstract: The present invention is an electrophotographic photoconductor having a photosensitive layer on a conductive substrate. The photosensitive layer contains trimellitimide esters additives.

Abstract: The present invention is an electrophotographic photoconductor having a photosensitive layer on a conductive substrate. The photosensitive layer contains terephthalate esters additives.

Abstract: The present invention is an electrophotographic photoconductor having a photosensitive layer on a conductive substrate. The photosensitive layer contains N-arylphthalimides additives.

Abstract: Disclosed are polymers which include tertiary aryl amine moieties that can function as hole transport agents and which also have reactive silane groups thereon capable of being condensed to a silsesquioxane composition, as well as the silsesquioxane compositions prepared therefrom. The silsesquioxanes can be coated onto substrates to form abrasion-resistant layers having hole transport properties useful in devices that require charge transport properties, such as light-emitting diodes and organic electrophotographic elements such as photoreceptors or photoconductors. Also disclosed are electrophotographic elements which comprise an electrically conducting layer, a charge generating layer overlying the electrically conducting layer, and a charge transport layer overlying the electrically conducting layer. The charge transport layer, which can be an overcoat overlying the charge generating layer, comprises the condensed reaction product of the disclosed polymers.

Abstract: The present invention relates to photoconductive elements having an electrically conductive support, an electrical barrier layer and, disposed over the barrier layer, a charge generation layer capable of generating positive charge carriers when exposed to actinic radiation. The electrical barrier layer, which restrains injection of positive charge carriers from the conductive support, comprises a crosslinker, a crosslinkable condensation polymer having as a repeating unit a planar, electron-deficient, tetracarbonylbisimide group.

Abstract: The present invention is an electrophotographic photoconductor having a photosensitive layer on a conductive substrate. The photosensitive layer contains trimellitimide esters additives.

Abstract: The present invention is an electrophotographic photoconductor having a photosensitive layer on a conductive substrate. The photosensitive layer contains N-arylphthalimides additives.

Abstract: The present invention is an electrophotographic photoconductor having a photosensitive layer on a conductive substrate. The photosensitive layer contains terephthalate esters additives.

Abstract: The present invention relates to photoconductive elements having an electrically conductive support, an electrical barrier layer and, disposed over the conductive layer, a charge generation layer capable of generating positive charge carriers when exposed to actinic radiation.

Abstract: The present invention is a photoconductive element that includes an electrically conductive support, an electrical barrier layer disposed over said electrically conductive support, and disposed over said barrier layer, a charge generation layer capable of generating positive charge carriers when exposed to actinic radiation. The barrier layer includes a vinyl polymer with aromatic tetracarbonylbisimide side groups and crosslinking sites.

Abstract: Diesel engine exhaust filtration systems, and ceramic honeycomb wall flow exhaust filters for such systems, wherein the filters comprise axially centralized filter sections having a higher heat capacity and/or a higher gas flow resistance than peripheral filter sections disposed radially outwardly thereof, the filters thereby exhibiting increased resistance to thermal damage from filter regeneration over-heating.

Abstract: A multi-active electrophotographic charge generation element comprises a conductive support, a charge generation layer (CGL) disposed on the conductive support, and a charge transport layer (CTL) disposed on the charge generation layer. The charge generation layer (CGL) includes a charge-generation material comprising an aggregated or crystalline form of a first dye or pigment and a first polymeric binder. The charge transport layer (CTL) comprises at least one charge-transport agent, a second dye or pigment having absorption in a selected spectral region that at least partially overlaps the absorption of a dissolved non-aggregated or non-crystalline form of the first dye or pigment, and a second polymeric binder. The second dye or pigment in the charge transport layer absorbs radiation in the selected spectral region that is incident on the charge transport layer, thereby shielding the charge generation layer from that radiation and mitigating visible radiation-induced photofatigue.

Abstract: Disclosed are photoconductive elements including a conductive support, e.g., an electrically conductive film, drum, or belt, on which a negatively chargeable photoconductive layer is disposed. An electrical barrier layer is disposed between the conductive support and the photoconductive layer. The barrier layer provides a high energy barrier to the injection of positive charges, but transports electrons under an applied electric field. In embodiments, the barrier layer can transport charge by electronic mechanisms, and, is not substantially affected by humidity changes. The barrier layer includes a polyamide-co-imide having covalently bonded as repeat units in the polymer chain, aromatic tetracarbonylbisimide groups of the formula: wherein Ar1 and Ar2 respectively represent tetravalent or trivalent aromatic groups of 6 to about 20 carbon atoms, and X is O, C(CF3)2, S?O or SO2.

Abstract: Disclosed are polymers which include tertiary aryl amine moieties that can function as hole transport agents and which also have reactive silane groups thereon capable of being condensed to a silsesquioxane composition, as well as the silsesquioxane compositions prepared therefrom. The silsesquioxanes can be coated onto substrates to form abrasion-resistant layers having hole transport properties useful in devices that require charge transport properties, such as light-emitting diodes and organic electrophotographic elements such as photoreceptors or photoconductors. Also disclosed are electrophotographic elements which comprise an electrically conducting layer, a charge generating layer overlying the electrically conducting layer, and a charge transport layer overlying the electrically conducting layer. The charge transport layer, which can be an overcoat overlying the charge generating layer, comprises the condensed reaction product of the disclosed polymers.

Abstract: Disclosed are photoconductive elements including a conductive support, e.g., an electrically conductive film, drum, or belt, on which a negatively chargeable photoconductive layer is disposed. An electrical barrier layer is disposed between the conductive support and the photoconductive layer. The barrier layer provides a high energy barrier to the injection of positive charges, but transports electrons under an applied electric field. In embodiments, the barrier layer can transport charge by electronic mechanisms, and, is not substantially affected by humidity changes.