Patents by Inventor David Sabatino

David Sabatino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azapeptides as CD36 binding compounds
    Patent number: 9708370
    Abstract: An azapeptide compound of Formula I: A-(Xaa)a-N(RA)—N(RB)—C(O)-(Xaa?)b-B ??I.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: July 18, 2017
    Assignees: VALORISATION-RECHERCHE, LIMITED PARTNERSHIP, VALORISATION HSJ, LIMITED PARTNERSHIP
    Inventors: Huy Ong, Sylvain Chemtob, William Lubell, Florian Sennlaub, Damien Boeglin, Caroline Proulx, Zohreh Sajjadi, David Sabatino
  • Functionalized fluorine containing phthalocyanine molecules
    Patent number: 9572898
    Abstract: Functionalized fluorine containing phthalocyanine molecules, methods of making, and methods of use in diagnostic applications and disease treatment are disclosed herein. In some embodiments, the fluorine containing phthalocyanine molecules are functionalized with a reactive functional group or at least one cancer-targeting ligand (CTL). The CTL can facilitate more efficient binding and/or internalization to a cancer cell than to a healthy cell. The CTL can inhibit expression of oncoprotein in some embodiments. The pthalocyanine moiety can be used in diagnostic applications, such as fluorescence labeling of a cancer cell, and/or treatment applications, such as catalyzing formation of a reactive oxygen species (ROS) which can contribute to cell death of a cancer cell.
    Type: Grant
    Filed: September 9, 2014
    Date of Patent: February 21, 2017
    Assignee: Seton Hall University
    Inventors: David Sabatino, Sergiu M. Gorun, Emily Borland, Hemantbhai Patel, Pradeepkumar Patel, Erik Nathaniel Carrión
  • AZAPEPTIDES AS CD36 BINDING COMPOUNDS
    Publication number: 20150329591
    Abstract: An azapeptide compound of Formula I: A-(Xaa)a-N(RA)—N(RB)—C(O)-(Xaa?)b-B
    Type: Application
    Filed: July 28, 2015
    Publication date: November 19, 2015
    Inventors: Huy ONG, Sylvain CHEMTOB, William LUBELL, Florian SENNLAUB, Damien BOEGLIN, Caroline PROULX, Zohreh SAJJADI, David SABATINO
  • Azapeptides as CD36 binding compounds
    Patent number: 9115171
    Abstract: An azapeptide compound of Formula I: A-(Xaa)a-N(RA)—N(RB)—C(O)-(Xaa?)b-B??I.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: August 25, 2015
    Assignees: VALORISATION-RECHERCHE, LIMITED PARTNERSHIP, VALORISATION HSJ, LIMITED PARTNERSHIP
    Inventors: Huy Ong, Sylvain Chemtob, William Lubell, Florian Sennlaub, Damien Boeglin, Caroline Proulx, Zohreh Sajjadi, David Sabatino
  • FUNCTIONALIZED FLUORINE CONTAINING PHTHALOCYANINE MOLECULES
    Publication number: 20150071862
    Abstract: Functionalized fluorine containing phthalocyanine molecules, methods of making, and methods of use in diagnostic applications and disease treatment are disclosed herein. In some embodiments, the fluorine containing phthalocyanine molecules are functionalized with a reactive functional group or at least one cancer-targeting ligand (CTL). The CTL can facilitate more efficient binding and/or internalization to a cancer cell than to a healthy cell. The CTL can inhibit expression of oncoprotein in some embodiments. The pthalocyanine moiety can be used in diagnostic applications, such as fluorescence labeling of a cancer cell, and/or treatment applications, such as catalyzing formation of a reactive oxygen species (ROS) which can contribute to cell death of a cancer cell.
    Type: Application
    Filed: September 9, 2014
    Publication date: March 12, 2015
    Inventors: David Sabatino, Sergiu M. Gorun, Emily Borland, Hemantbhai Patel, Pradeepkumar Patel
  • AZAPEPTIDES AS CD36 BINDING COMPOUNDS
    Publication number: 20130203686
    Abstract: An azapeptide compound of Formula I: A-(Xaa)a-N(RA)—N(RB)—C(O)-(Xaa?)b—B??I.
    Type: Application
    Filed: March 14, 2013
    Publication date: August 8, 2013
    Inventors: Huy Ong, Sylvain Chemtob, William Lubell, Florian Sennlaub, Damien Boeglin, Caroline Proulx, Zohreh Sajjadi, David Sabatino
  • Azapeptides as CD36 binding compounds
    Patent number: 8435954
    Abstract: An azapeptide derivative of growth hormone releasing peptide (GHRP) of Formula I: A-(Xaa)a-N(RA)—N(RB)—C(O)-(Xaa?)b-B which binds to CD 36.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: May 7, 2013
    Assignees: Valorisation-Recherche, Limited Partnership, Valorisation HSJ, Limited Partnership
    Inventors: Huy Ong, Sylvain Chemtob, William Lubell, Florian Sennlaub, Damien Boeglin, Caroline Proulx, Zohreh Sajjadi, David Sabatino
  • AZAPEPTIDES AS CD36 BINDING COMPOUNDS
    Publication number: 20100210566
    Abstract: An azapeptide derivative of growth hormone releasing peptide (GHRP) of Formula I: A-(Xaa)a-N(RA)—N(RB)—C(O)-(Xaa?)b-B which binds to CD 36.
    Type: Application
    Filed: June 18, 2008
    Publication date: August 19, 2010
    Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Huy Ong, Sylvain Chemtob, William Lubell, Florian Sennlaub, Damien Boeglin, Caroline Proulx, Zohreh Sajjadi, David Sabatino