Abstract: An applicator instrument for dispensing surgical fasteners includes a housing, and an elongated shaft extending from the housing. The elongated shaft has a proximal end secured to the housing, a distal end spaced from the proximal end, and a first axis extending between the proximal and distal ends of the elongated shaft. Surgical fasteners are disposed in the elongated shaft. The surgical fasteners are stacked at an angle relative to the first axis of the elongated shaft. A distal end cap having a surgical fastener dispensing window is secured to the distal end of the elongated shaft. The applicator instrument has a firing system disposed in the housing, and an actuator coupled with the firing system for activating the firing system to dispense the surgical fasteners through the surgical fastener dispensing window.

Abstract: Systems, methods, and non-transitory media are provided for low latency handovers. An example method can include receiving, by a satellite, a schedule of communications between the satellite and one or more gateways; requesting, based on the schedule, a handover from a link between the satellite and a gateway to a different link between the satellite and the gateway or a different gateway; prior to a completion of the handover, processing packets bicasted over the link between the satellite and the gateway and the different link between the satellite and the gateway or the different gateway; performing the handover from the link between the satellite and the gateway to the different link between the satellite and the gateway or the different gateway; and after the handover, transmitting, by the satellite, one or more packets via the different link between the satellite and the gateway or the different gateway.

Abstract: Systems, methods, and non-transitory media are provided for low latency handovers. An example method can include receiving, by a user terminal associated with a cell served by a satellite, a schedule of communications between the user terminal and one or more satellites, wherein the one or more satellites comprises the satellite and a different satellite, and wherein the schedule of communications is obtained by the user terminal from the satellite; requesting, based on the schedule, a handover from a beam of the satellite to a different beam of one of the satellite or the different satellite; performing the handover from the beam of the satellite to the different beam of the one of the satellite or the different satellite; and after the handover, transmitting, by the user terminal, one or more packets via the different beam of the one of the satellite or the different satellite.

Abstract: In an embodiment, a user terminal includes a communication module (CM) configured to generate an initial network entry request; an antenna assembly configured to find, in response to the initial network entry request, a satellite based on a search of a sky. The search of the sky includes sequentially changing a beam pointing direction of the antenna assembly. The satellite is assigned to downlink to a geographic cell associated with the user terminal. The user terminal includes a media access control (MAC) layer component configured to generate an uplink radio frame including a random access channel (RACH) request associated with the initial network entry request at a particular portion of the uplink radio frame for the satellite.

Abstract: In an embodiment, a user terminal includes a connection manager component configured to generate an initial network entry request; an antenna assembly communicatively coupled to the connection manager and configured, in response to the initial network entry request, to find a satellite based on a search of a sky, wherein the satellite comprises a satellite assigned to downlink to a geographic cell associated with the user terminal; and a media access control (MAC) layer component communicatively coupled to the connection manager, the MAC layer component configured to generate an uplink radio frame including a random access channel (RACH) request associated with the initial network entry request at a particular portion of the uplink radio frame for the satellite, wherein the particular portion is selected by the MAC layer component from among a plurality of portions of the uplink radio frame.

Abstract: Systems, methods, and non-transitory media are provided for low latency handovers. An example method can include receiving, by a user terminal associated with a cell served by a satellite, a schedule of communications between the user terminal and one or more satellites; requesting, based on the schedule, a handover from a beam of the satellite to a different beam of one of the satellite or a different satellite; processing packets transmitted over the beam of the satellite and/or the different beam of the one of the satellite or the different satellite; performing the handover from the beam of the satellite to the different beam of the one of the satellite or the different satellite; and after the handover, transmitting, by the user terminal, one or more packets via the different beam of the one of the satellite or the different satellite.

Abstract: Provided herein are polypeptides comprising up to 9 antigenic elements of ETEC virulence determinants: 7 CFA adhesins [CFA/I, CFA/II (CS1, CS2, CS3), CFA/IV (CS4, CS5, CS6)] expressed by the most prevalent and virulent ETEC strains, and 2 toxins expressed by all ETEC strains, were genetically fused together for CFA-toxoid fusion with proteins (CFA/I/II/IV-STatoxoid-LTtoxoid). Methods for making these polypeptides and their use in the treatment of ETEC related disease are also provided.

Abstract: Provided herein are polypeptides comprising up to 9 antigenic elements of ETEC virulence determinants: 7 CFA adhesins [CFA/I, CFA/II (CS1, CS2, CS3), CFA/IV (CS4, CS5, CS6)] expressed by the most prevalent and virulent ETEC strains, and 2 toxins expressed by all ETEC strains, were genetically fused together for CFA-toxoid fusion with proteins (CFA/I/II/IV-STa-toxoid-LTtoxoid). Methods for making these polypeptides and their use in the treatment of ETEC related disease are also provided.

Abstract: Provided herein are polypeptides comprising up to 9 antigenic elements of ETEC virulence determinants: 7 CFA adhesins [CFA/I, CFA/II (CS1, CS2, CS3), CFA/IV (CS4, CS5, CS6)] expressed by the most prevalent and virulent ETEC strains, and 2 toxins expressed by all ETEC strains, were genetically fused together for CFA-toxoid fusion with proteins (CFA/I/II/IV-STa-toxoid-LTtoxoid). Methods for making these polypeptides and their use in the treatment of ETEC related disease are also provided.

Abstract: Provided herein are polypeptides comprising up to 9 antigenic elements of ETEC virulence determinants: 7 CFA adhesins [CFA/I, CFA/II (CS1, CS2, CS3), CFA/IV (CS4, CS5, CS6)] expressed by the most prevalent and virulent ETEC strains, and 2 toxins expressed by all ETEC strains, were genetically fused together for CFA-toxoid fusion with proteins (CFA/I/II/IV-STatoxoid-LTtoxoid). Methods for making these polypeptides and their use in the treatment of ETEC related disease are also provided.

Abstract: Provided herein are polypeptides comprising up to 9 antigenic elements of ETEC virulence determinants: 7 CFA adhesins [CFA/I, CFA/II (CS1, CS2, CS3), CFA/IV (CS4, CS5, CS6)] expressed by the most prevalent and virulent ETEC strains, and 2 toxins expressed by all ETEC strains, were genetically fused together for CFA-toxoid fusion with proteins (CFA/I/II/IV-STa-toxoidLTtoxoid). Methods for making these polypeptides and their use in the treatment of ETEC related disease are also provided.

Abstract: Provided herein are polypeptides comprising up to 9 antigenic elements of ETEC virulence determinants: 7 CFA adhesins [CFA/I, CFA/II (CS1, CS2, CS3), CFA/IV (CS4, CS5, CS6)] expressed by the most prevalent and virulent ETEC strains, and 2 toxins expressed by all ETEC strains, were genetically fused together for CFA-toxoid fusion with proteins (CFA/I/II/IV-STa-toxoidLTtoxoid). Methods for making these polypeptides and their use in the treatment of ETEC related disease are also provided.

Abstract: A food composition having a high protein level and comprising DHA, preferably for use as a meal replacement, is administered to subjects in order to control their weight.

Abstract: The present disclosure provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present disclosure also provides compositions for vaccines to prevent Leishmaniasis.

Abstract: The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis.

Abstract: A system and method for a networked viral family tree are disclosed. According to one embodiment, a computer-implemented method, comprises receiving a first profile from a first client. The first profile includes a first e-mail address. A second e-mail address is received from the first client. The second e-mail address is associated with a second profile. The second profile is created dynamically when the client provides the second e-mail address. An invitation is sent to the second e-mail address to provide additional profile information associated with the second profile. One or more relationships are associated to the first profile and the second profile to generate a family tree. One or more user interfaces is provided through which the first client provides a plurality of e-mail addresses corresponding to members of the family tree and are associated with of a plurality of profiles.

Abstract: The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis.

Abstract: The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis.

Abstract: A method and kit for the detection of an infectious disease, particularly tuberculosis, wherein lymphocytes of a subject are incubated with a disease-specific antigen, and the level of antibody production is measured, the production of antibodies above a baseline level being indicative of infection.

Abstract: The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis.