Patents by Inventor David SEGHETTI

David SEGHETTI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEXT-GENERATION SEQUENCING FOR PROTEIN MEASUREMENT
    Publication number: 20260104409
    Abstract: Methods of detecting and quantifying target molecules, such as proteins, in a biological sample are provided. The disclosed methods include capturing target molecules with aptamers, replacing the aptamers with aptamer identification sequences, and then sequencing the aptamer identification sequences using next-generation sequencing techniques.
    Type: Application
    Filed: December 12, 2025
    Publication date: April 16, 2026
    Inventors: Dom ZICHI, Allison WEISS, David SEGHETTI, Kathryn JENKO
  • Next-generation sequencing for protein measurement
    Patent number: 12498365
    Abstract: Tri-molecular complexes and related systems for quantifying the abundances of target molecules in a biological sample are provided. The disclosed tri-molecular complexes each include an aptamer, a first capture probe hybridized to a first portion of the aptamer, and a second capture probe hybridized to a second portion of the aptamer. The second capture probe further includes an aptamer identification sequence that may be used to identify the aptamer, and thereby to identify the target molecule to which the aptamer is configured to bind.
    Type: Grant
    Filed: March 29, 2024
    Date of Patent: December 16, 2025
    Assignee: SomaLogic Operating Co., Inc.
    Inventors: Dom Zichi, Allison Weiss, David Seghetti, Kathryn Jenko
  • NEXT-GENERATION SEQUENCING FOR PROTEIN MEASUREMENT
    Publication number: 20240241112
    Abstract: Methods of detecting and quantifying target molecules, such as proteins, in a biological sample are provided. The disclosed methods include capturing target molecules with aptamers, replacing the aptamers with aptamer identification sequences, and then sequencing the aptamer identification sequences using next-generation sequencing techniques.
    Type: Application
    Filed: March 29, 2024
    Publication date: July 18, 2024
    Inventors: Dom ZICHI, Allison WEISS, David SEGHETTI, Kathryn JENKO
  • Next-generation sequencing for protein measurement
    Patent number: 11965880
    Abstract: Methods of detecting and quantifying target molecules, such as proteins, in a biological sample are provided. The disclosed methods include capturing target molecules with aptamers, replacing the aptamers with aptamer identification sequences, and then sequencing the aptamer identification sequences using next-generation sequencing techniques.
    Type: Grant
    Filed: December 29, 2022
    Date of Patent: April 23, 2024
    Assignee: SomaLogic Operating Co., Inc.
    Inventors: Dom Zichi, Allison Weiss, David Seghetti, Kathryn Jenko
  • NEXT-GENERATION SEQUENCING FOR PROTEIN MEASUREMENT
    Publication number: 20230213502
    Abstract: Methods of detecting and quantifying target molecules, such as proteins, in a biological sample are provided. The disclosed methods include capturing target molecules with aptamers, replacing the aptamers with aptamer identification sequences, and then sequencing the aptamer identification sequences using next-generation sequencing techniques.
    Type: Application
    Filed: December 29, 2022
    Publication date: July 6, 2023
    Inventors: Dom ZICHI, Allison WEISS, David SEGHETTI, Kathryn JENKO