Abstract: A chemiluminescent substrate of a hydrolytic enzyme having the following general Formula I is disclosed, as follows: Lumi-M-P ??Formula I where “Lumi” is a chemiluminescent moiety capable of producing light (a) by itself, (b) with MP attached and (c) with M attached. Examples of Lumi include chemiluminescent acridinium compounds, benzacridinium compounds, quinolinium compounds, isoquinolinium compounds, phenanthridinium compounds, and lucigenin compounds, spiroacridan compounds, luminol compounds and isoluminol compounds. M is a multivalent heteroatom having at least one lone pair of electrons selected from oxygen, nitrogen and sulfur, directly attached to the light emitting moiety of Lumi at one end and to P at the other end. P is a group that can be readily removed by hydrolytic enzymes. An enzymatic reaction utilizing the above compound is the following: where HE is a hydrolytic enzyme. Lumi-M is a chemiluminescent product having physical and/or chemical properties different from those of Lumi-M-P.

Abstract: A method for the detection or quantitation of an analyte in a biological sample is disclosed. The method comprises the steps of selecting a biological sample suspected of containing a target analyte and binding the target analyte in the sample to a binding partner conjugated to an acridinium compound, wherein the acridinium compound comprises an acridinium nucleus having an electron-donating substituent directly attached to the acridinium nucleus at the C2 position. Chemiluminescent acridinium compounds useful in the method have emission maxima close to or in the near infrared (NIR) region (>590 nm). These chemiluminescent acridinium compounds when used in conjunction with short wavelength-emitting acridinium esters (with emission maxima below 450 nm) can be highly useful labels for the simultaneous detection of multiple target analytes in a single assay.

Abstract: An apparatus for generating carbon monoxide comprising an enclosure (6) having an inlet and an outlet at least one of which is provided with means (8) restricting air flow from the inlet to the outlet, a container (1) located within the enclosure (6) arranged to receive carbon material (2) in intimate contact with an electrical heating element (3), and means (5) for causing air to move from the inlet to the outlet.

Abstract: Disclosed is a data processing system implemented method, a data processing system and an article of manufacture for executing a query having a union operator. A data processing system implemented method direct the data processing system to execute a query against a database having data objects. The query has sub-queries and having a union operator. The union operator is operable on sub-queries associated with the query. The database is operatively coupled to the data processing system.

Abstract: Disclosed is a data processing system implemented method, a data processing system and an article of manufacture for executing a query having a union operator. The data processing system implemented method directs the data processing system to process a query against data objects. The data objects are operatively coupled to the data processing system. The query includes a parent operator. The parent operator references a union operator. The union operator references sub-queries. The sub-queries reference the data objects. The data processing system implemented method includes noting a set of partitionings for the union operator, the noted set of partitionings being based on the sub-queries and being based on the data objects reference by the sub-queries, and executing the query having the union operator, the execution of the query being based on the noted set of partitionings and the parent operator.

Abstract: Disclosed is a data processing system, a data processing system implemented method and an article of manufacture for executing a query having a union all operator. The data processing system implemented method directs the data processing system to execute a query against a data object. The query has a union all operator and has a set of data modifying operators. The set of data modifying operators is associated with the union all operator. The union all operator references the data object. The data processing system implemented method includes preventing the union all operator from being applied to the data object, and applying the set of data modifying operators against the data object.

Abstract: A method and system that allows the user to fetch a subsequent web page while maintaining the current web page as the active web page. The next web page is fetched “in the background” and stored in cache memory without interrupting the user. Once the requested web page has been stored in cache, an indicator is added to the history list allowing the user access to the processed web page. In order to view the next web page, the user simply selects the appropriate icon on the user interface, such as the forward button which is akin to selecting the back or forward button to scroll through the history of web pages. Since the web page is in the cache, it is displayed relatively quickly and since the user selects when to display the page, there is no interruption.

Abstract: The present invention relates to a process for the production of a frozen vegetable or part thereof, wherein said process comprises the steps: (i) heat-treating a vegetable or part thereof; (ii) under-cooling to a maximum core temperature of less than or equal to ?5° C.; (iii) reducing the core temperature to less than or equal to ?18° C.; The invention also provides a frozen vegetable or part thereof comprising a core ice content, characterised in that at least 40% of said core ice content is located within a plurality of cellular structures, wherein the perimeter of each cellular structure is defined by a cell wall.

Abstract: The present invention relates to hydrophilic, high quantum yield acridinium compounds. It has been discovered that the placement of electron-donating groups in the acridinium ring system increases the amount of light that is emitted by the corresponding acridinium compound when its chemiluminescence is triggered by alkaline peroxide. More specifically, it has been found that the placement of one or two hydrophilic, alkoxy groups at the C-2 and/or C-7 position of the acridinium ring system of acridinium compounds increases their quantum yield and enhances the aqueous solubility of these compounds. The present hydrophilic, high quantum yield, acridinium compounds are useful chemiluminescent labels for improving the sensitivity of immunoassays.

Abstract: A shadow box scrapbook page adapted to hold and secure three-dimensional objects for storage and display. This invention provides a binder portion having openings to receive standard rings or posts common to binders, and a frame device, having a front, back and side, top and bottom sections, defining a cavity. The front is generally transparent for the viewing of the stored objects.

Abstract: A chemiluminescent substrate of a hydrolytic enzyme having the following general Formula I is disclosed, as follows: Lumi-M-P??Formula I where “Lumi” is a chemiluminescent moiety capable of producing light (a) by itself, (b) with MP attached and (c) with M attached. Examples of Lumi include chemiluminescent acridinium compounds, benzacridinium compounds, quinolinium compounds, isoquinolinium compounds, phenanthridinium compounds, and lucigenin compounds, spiroacridan compounds, luminol compounds and isoluminol compounds. M is a multivalent heteroatom having at least one lone pair of electrons selected from oxygen, nitrogen and sulfur, directly attached to the light emitting moiety of Lumi at one end and to P at the other end. P is a group that can be readily removed by hydrolytic enzymes. An enzymatic reaction utilizing the above compound is the following: where HE is a hydrolytic enzyme. Lumi-M is a chemiluminescent product having physical and/or chemical properties different from those of Lumi-M-P.

Abstract: A query processing system has a query processor and a data manager. The query processor calls the data manager to carry out data access for a query including a filtering operation. The data manager accesses the data in a set of data and before returning the data, initiates a callback to the query processor to determine if the located data meets the filtering criteria. Where the data does not satisfy the filtering criteria, the data manager seeks additional data in the set of data, without having to return the first located data to the query processor.

Abstract: Chemiluminescent acridinium compounds are used in homogeneous assays to determine the concentration of an analyte in a sample without strong acid or strong base treatment. The chemiluminescent acridinium compounds include acridinium esters with electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus to inhibit pseudo-base formation, or acridinium sulfonamides with or without electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus.

Abstract: A system and method for displaying property information, such as time or size information, on a display without displaying the textual column for these properties. The method compares predetermined properties of an item to a threshold value and assigns varying display indicators to the items based on the item's properties. The varying display indicators, such as colored fonts, have a variable quality such that as the relative properties for the item change, the variable indicator may also change accordingly. Additionally, the system and method updates the threshold value and the assigned variable visual indicators so the display characteristics change as the value changes. Thus, information is displayed to the user based on relative properties of the item without displaying explicit text.

Abstract: An apparatus for rolling of a powder metallurgical metallic workpiece is provided having a feeding device, a first induction heating apparatus in operable communication with a first RF generator and at least a first hot rolling mill. A process control device monitors at least one parameter of the first RF generator and outputs a signal. A method for continuous rolling of a metallic workpiece is also provided using the apparatus for rolling. The process control device signal can be used to monitor metallurgical properties of the workpiece and provide in-line evaluation of the workpiece.

Abstract: The present invention discloses a method for the measurement of hydride using a chemiluminescent compound. The preferred chemiluminescent molecule is an acridinium compound. The source of hydride for the reduction of acridinium compound may be of chemical or biochemical origin, or the result of enzymatic catalysis. The chemical source of hydride, for example, might be metal hydrides, such as NaBH4. A biochemical source of hydride might be that derived from NADH, or NADPH, while an enzymatic source would be the class of oxidoreductases termed dehydrogenases which convert NADH or NADPH from NAD or NADP. There are numerous potential applications for acridinium compounds as chemiluminescent indicators of hydride. Any applied tests or diagnostic assays, in which hydride is either present at the onset of or generated through the course of a reaction, would benefit from the present invention.

Abstract: The present invention is generally directed to detectable chemiluminescent acridinium ester labels having hydrophilic modifiers; to compositions, complexes and/or conjugates which include such labels; and to processes for performing bioanalytical assays for target analytes which use such labels. Assays for folate, theophylline, and tobramycin (using such labels with hydrophilic modifiers such as nonionic polyethylene glycol and polyionic spermine disulfonate and polyionic spermine dicarboxylate) are described in detail.

Abstract: A system and method for displaying lists of items, such as documents or email messages, wherein the method displays size information without displaying the textual column for this property. The method converts the size information into a percentage of the space in the row. Next, the method shades, in a light color, the calculated percentage of the background space in the row for that item. The shading may begin at the left-hand boundary and continue towards the right-hand boundary. Tick marks and/or values may be displayed in the column headers to indicate the relative sizes based on the shaded background. The shading may otherwise be fixed or relative to the largest item in the list or the both the largest and the smallest items in the list.

Abstract: The present invention is generally directed to detectable chemiluminescent acridinium ester labels having hydrophilic modifiers; to compositions, complexes and/or conjugates which include such labels; and to processes for performing bioanalytical assays for target analytes which use such labels. Assays for folate, theophylline, and tobramycin (using such labels with hydrophilic modifiers such as nonionic polyethylene glycol and polyionic spermine disulfonate and polyionic spermine dicarboxylate) are described in detail.

Abstract: An application specific integrated circuit (ASIC) and method of manufacture. The ASIC includes a substrate layer, at least one metal layer and an operational block. The metal layer is formed above the substrate layer. The operational block is formed in the substrate layer and the metal layer, and is definable by a two-dimensional boundary. The operational block includes a plurality of operational logic gates, a first subgroup of spare logic gates, a second subgroup of spare logic gates, operational wiring and spare gate wiring. The operational logic gates, the first subgroup and the second subgroup are formed on the substrate layer, with the first subgroup being spaced from the second subgroup. The operational wiring is routed into the metal layer and interconnects the operational logic gates to configure the operational block to perform a desired operation. The spare gate wiring is similarly routed into the metal layer.