Abstract: The present disclosure includes certain steps in immunoassays, such as immunoassays based on chemiluminescence, which increase assay sensitivity as based on a variety of metrics including increasing signal to noise and decreasing limits of detection. One strategy for these enhancements involves movement, and potential sequestration, of solid phases in one triggering reagent prior to addition of a second triggering reagent for chemiluminescence.

Abstract: A money handling system includes: a plurality of money handling apparatuses configured to perform money handling; and a management apparatus communicably connected to the plurality of money handling apparatuses and configured to acquire, from each money handling apparatus, information on an inventory quantity for each kind of money in the apparatus. The plurality of money handling apparatuses are separated into a plurality of groups, and the management apparatus manages an inventory quantity for each kind of money by group, and requests replenishment or collection of money for each money handling apparatus, based on a threshold for each kind of money set for each group in addition to an inventory quantity for each kind of money in each money handling apparatus.

Abstract: A cash transport system includes a cash handling apparatus installed in a store, and a management device. The management device includes circuitry configured to: determine whether cash transport to the store for replenishing the cash handling apparatus with cash is necessary; determine whether cash transport from the store for collecting cash from the cash handling apparatus is necessary; in a case that the circuitry has determined that any of the cash transport to the store and the cash transport from the store is necessary, calculate, based on one currency selected in advance from among the plurality of currencies, a transport amount by converting the amounts of cash of currencies to be transported into amounts of the selected currency and summing up the converted amounts; and in a case that the transport amount exceeds a upper-limit amount, notify a communication terminal that the transport amount exceeds the upper-limit amount.

Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.

Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.

Abstract: A cash transport system includes a cash handling apparatus installed in a store, and a management device. The management device includes circuitry configured to: determine whether cash transport to the store for replenishing the cash handling apparatus with cash is necessary; determine whether cash transport from the store for collecting cash from the cash handling apparatus is necessary; in a case that the circuitry has determined that any of the cash transport to the store and the cash transport from the store is necessary, calculate, based on one currency selected in advance from among the plurality of currencies, a transport amount by converting the amounts of cash of currencies to be transported into amounts of the selected currency and summing up the converted amounts; and in a case that the transport amount exceeds a upper-limit amount, notify a communication terminal that the transport amount exceeds the upper-limit amount.

Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.

Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.

Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.

Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.

Abstract: Systems and methods for facilitating use of physical tokens in a transit system are disclosed. In one implementation, a method for facilitating use of physical tokens by a server includes generating a token identifier and generating, using a private key associated with the server, a cryptographic signature based on the token identifier. The method further includes transmitting the token identifier and the cryptographic signature to a token dispenser. The token dispenser is configured to dispense a physical token, and the physical token is configured to provide the token identifier and the cryptographic signature to a token validator.

Abstract: Zwitterion-containing compounds for the modification of hydrophobic molecules to improve their solubility and/or to lower their non-specific binding as provided. The zwitterion-containing compounds may be suitable for modification of detectable labels such as biotin and fluorescein to improve their solubility. The zwitterion-containing compounds may also be useful for the preparation of conjugates of proteins, peptides and other macromolecules or for crosslinking molecules and/or macromolecules.

Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.

Abstract: Systems and methods for facilitating use of physical tokens in a transit system are disclosed. In one implementation, a method for facilitating use of physical tokens by a server includes generating a token identifier and generating, using a private key associated with the server, a cryptographic signature based on the token identifier. The method further includes transmitting the token identifier and the cryptographic signature to a token dispenser. The token dispenser is configured to dispense a physical token, and the physical token is configured to provide the token identifier and the cryptographic signature to a token validator.

Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.

Abstract: Hydrophilic, chemiluminescent acridinium compounds containing zwitterions are disclosed. These acridinium compounds, when used as chemiluminescent labels in immunochemistry assays and the like, exhibit decreased non-specific binding to solid phases and provide increased assay sensitivity.

Abstract: Zwitterion-containing compounds for the modification of hydrophobic molecules to improve their solubility and/or to lower their non-specific binding as provided. The zwitterion-containing compounds may be suitable for modification of detectable labels such as biotin and fluorescein to improve their solubility. The zwitterion-containing compounds may also be useful for the preparation of conjugates of proteins, peptides and other macromolecules or for crosslinking molecules and/or macromolecules.

Abstract: Zwitterion-containing compounds for the modification of hydrophobic molecules to improve their solubility and/or to lower their non-specific binding as provided. The zwitterion-containing compounds may be suitable for modification of detectable labels such as biotin and fluorescein to improve their solubility. The zwitterion-containing compounds may also be useful for the preparation of conjugates of proteins, peptides and other macromolecules or for crosslinking molecules and/or macromolecules.

Abstract: Zwitterion-containing compounds for the modification of hydrophobic molecules to improve their solubility and/or to lower their non-specific binding as provided. The zwitterion-containing compounds may be suitable for modification of detectable labels such as biotin and fluorescein to improve their solubility. The zwitterion-containing compounds may also be useful for the preparation of conjugates of proteins, peptides and other macromolecules or for crosslinking molecules and/or macromolecules.

Abstract: An input device enabling a computer user to provide a range of inputs. The device comprises a body made up of a lower portion and an upper portion; an output interface; and a plurality of movement detectors arranged with the body to detect movements of the input device and based thereon to generate input signals for a computer or other device coupled to the output interface. The movement detectors are arranged to detect rotation about first and second axes defined by rotational movement of the upper portion relative to the lower portion, and movement of a actuatable element carried on one of the lower portion and the upper portion and actuatable independently of the other of the lower portion and the upper portion. The input device further comprises translational movement detectors, enabling a user to further provide three translational inputs.