Abstract: Methods and systems for managing processes performed by a host device are disclosed. To manage the processes performed by the host device, the future state of operation of the host device performing the process may be identified. To identify the future state of operation, the actual state of operation at various points in time during performance of the process may be obtained. The actual state of operation may be obtained using information presented by a graphical user interface managed by a process performed by the host device at different points in time. By doing so, the identified future operating state may be used to manage the continued performance of the process to facilitate completion of the process.

Abstract: Methods and systems for managing processes performed by a host device are disclosed. To manage the processes performed by the host device, the actual state of operation of the host device performing the process may be identified. To identify the actual state of operation, out-of-band components of the host device such as a management controller may obtain information presented by a graphical user interface managed by a process performed by the host device. The information may be used to infer the actual operating state of the host device. By doing so, the actual operating state may be used to manage the operation of the host device.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: A valve system controls flow into a downhole production string, and which includes a downhole valve with a port formed in a sidewall of a production string disposed in a wellbore, and a sleeve that is slidable along the production string to block or allow flow through the port. An actuator assembly exerts a sliding force onto the sleeve, and is made up of multiple actuators arranged along an outer surface of the production string. Each actuator has an electrically powered motor and a stem connected to the motor. An opposite end of each stem connects to an end of the sleeve. Energizing the motors causes linear movement of the stems and connected sleeve to open and close the valve.

Abstract: Methods and systems for managing operation of infrastructure are disclosed. The operation of the infrastructure may be managed by managed by identifying solutions that are compatible with the infrastructure. The solutions may be identified through graph analysis of the infrastructure and requirements of various solutions. One or more of the compatible solutions may be selected and used to identify actions and policies for the infrastructure. When used by the infrastructure, the actions and policies may update the operating state of the infrastructure so that the selected solutions may be provided.

Abstract: The present disclosure relates to engineered T cells and methods of making and using the same, as well as reagents for making the engineered T cells.

Abstract: A method includes, by a computing system, receiving a querying image depicting a sampling area, processing the querying image using a single cluster detection model to identify one or more regions of the querying image depicting a cluster in the sampling area, processing the one or more regions using a cluster verification deep-learning model to determine whether each depicted cluster is a cell cluster, and determining that exactly one of the identified one or more regions depicts a cluster that is a cell cluster. The method further includes processing the region depicting the cell cluster using a morphology deep-learning model to determine that there is only one cell in the cell cluster and to determine that die morphology of the cell is acceptable.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: or a pharmaceutically acceptable salt, wherein the variables are as defined herein. Moreover, The compounds of this invention have formula I-A: or a pharmaceutically acceptable salt, wherein the variables are as defined herein.

Abstract: A graphical user interface is configured to guide a user through a method of creating a RESTful API protocol-compliant URL, without requiring that the user be familiar with syntax of the RESTful API protocol. The graphical user interface includes a URL output that indicates to the user features within a user-edited URL that render the user-edited URL non-compliant with the RESTful API protocol. The graphical user interface includes a set of graphical input devices to solicit and receive from the user input specifying a set of query options, which user input is used to define the RESTful API protocol-compliant URL. The graphical user interface is automatically customized to solicit and receive from the user input only for options available from a specific data service.

Abstract: A suppressor assembly is disclosed. The suppressor can comprise an outer tube defining a barrel axis, a first endcap configured to couple to a barrel of a firearm at a first end of the outer tube, and a spacer assembly in the outer tube. The spacer assembly can be positioned and/or captured between the first endcap and an exit side of the outer tube. The spacer assembly can comprise a plurality of spacers comprising a plurality of small and large diameter baffles oriented in different desirable positions within the spacer assembly. The baffles and spacers can be constructed from different materials so the weight of the baffles are greater than the weight of the spacers.

Abstract: A bi-directional valve with valve elements having compliant features biasing them together to maintain a sealing interface that defines a fluid communication barrier within the valve. Parting the valve elements from one another removes the sealing interface to allow fluid communication across the valve elements. The valve includes a side port and a choke member that selectively blocks fluid flow through the valve when moved adjacent the side port and selectively opens the valve to fluid communication when moved away from the side port. The choke member remains adjacent the side port until the valve elements are spaced a distance apart greater than that at which valve erosion or fluid cavitation occurs.

Abstract: A holding system includes a holder. The holder includes a peripheral lip and a flexible collar extending inward and downward from the peripheral lip. The flexible collar defines an opening configured to receive an object. The holding system further includes at least one of (a) a plurality of slide pads having at least a portion thereof positioned along an upper side of the flexible collar or (b) a biasing element extending along and around a periphery of an underside of the flexible collar.

Abstract: A bi-directional valve with valve elements having compliant features biasing them together to maintain a sealing interface that defines a fluid communication barrier within the valve. Parting the valve elements from one another removes the sealing interface allow fluid communication across the valve elements. The valve includes a side port and a choke member that selectively blocks fluid flow through the valve when moved adjacent the side port and selectively opens the valve to fluid communication when moved away from the side port. The choke member remains adjacent the side port until the valve elements are spaced a distance apart greater than that at which valve erosion or fluid cavitation occurs.

Abstract: A management service can receive an installation request for a client application from a first client device, where the installation request specifies a second client device on which the client application is to be installed. The management service can identify an operating system associated with the second client device. The management service can request installation of the client application on the second client device from an application catalog service associated with the operating system of the second client device.

Abstract: A method is disclosed for providing a tuned mass damper for a powertrain component. The method includes the steps of providing a mount adapted to be attached to the powertrain component; assembling a mass element to the mount; and molding an elastomeric body around the mass element to bond the mass element to the mount. The tuned mass damper assembly for a drivetrain component is also disclosed that may be attached to a mount having an opening that extends through the mount or a housing portion provided on the mount The molded elastomeric body integrally attaches the mass element to the mount. Alternatively, the tuned mass assembly may be bonded to a plate that is attached to a motor retention element.

Abstract: A firearm accessory mounting device is disclosed, comprising a nut, a collar coupled to the nut, and a follower captured between the collar and within a cam track of the nut. When the nut is rotated relative to the collar, threaded engagement secures the nut to the collar. Once the threaded engagement causes a torque threshold to be reached, further rotation of the nut causes the follower to extend radially inward to create a compressive force on a muzzle device and quickly and stably attach the firearm accessory mounting device.

Abstract: Disclosed are various approaches for workflow service back end integration. In some examples, a command is transmitted causing a client device to present a workflow action to perform. A user command to perform the workflow action is identified using the client device. Authentication data including user credentials and a navigation action for a visual user interface is identified. The user credentials are transmitted to the network service and an emulation of the navigation action is performed. A command that performs the workflow action is transmitted to the network service.

Abstract: A beverage holder includes a frame, an insert, and a cover. The frame includes a sidewall having an upper end and a lower end, and a bottom wall extending across the lower end. The upper end defines a plurality of protrusions. The sidewall and the bottom wall cooperatively define a chamber. The insert includes a peripheral rim defining a plurality of apertures that receive the plurality of protrusions and a flexible collar extending from the peripheral rim and at least partially into the chamber. The flexible collar defines an opening leading to the chamber. The cover includes a plurality of interfaces that engage with the plurality of protrusions to couple the cover to the upper end of the sidewall and to secure the insert between the frame and the cover. The cover defines an aperture that aligns with the chamber and the opening.

Abstract: A graphical user interface is configured to guide a user through a method of creating an OData-compliant URL, without requiring that the user be familiar with syntax of OData-compliant URLs. The graphical user interface includes a set of graphical input devices to solicit and receive from the user input specifying a set of query options, which user input is used to define the OData-compliant URL. The graphical user interface is automatically customized to solicit and receive from the user input only for options available from a specific OData service.