Patents by Inventor David Shivak

David Shivak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ZINC FINGER NUCLEASE VARIANTS FOR TREATING OR PREVENTING LYSOSOMAL STORAGE DISEASES
    Publication number: 20230048224
    Abstract: The present disclosure provides 2-in-1 zinc finger nuclease variants and methods of treating and/or preventing a lysosomal storage disorder using said zinc finger nuclease variants.
    Type: Application
    Filed: October 30, 2020
    Publication date: February 16, 2023
    Inventors: Gustavo De Alencastro, Marshall Huston, David Shivak
  • Use of biomolecular targets in the treatment and visualization of brain tumors
    Publication number: 20070025997
    Abstract: The present invention relates to the use of proteins that are differentially expressed in primary brain tumor tissues, as compared to normal brain tissues, as biomolecular targets for brain tumor treatment therapies. Specifically, the present invention relates to the use of therapeutic and imaging agents, which specifically bind to one or more of the identified brain tumor protein targets. The present invention also provides compounds and pharmaceutically acceptable compositions for administration in the methods of the invention. Nucleic acid probes specific for the spliced mRNA encoding these variants and affinity reagents specific for the novel proteins are also provided.
    Type: Application
    Filed: April 27, 2006
    Publication date: February 1, 2007
    Inventors: Usha Nagavarapu, David Shivak, Daniel Chin, Erik Foehr, Mirella Gonzalez-Zulueta