Patents by Inventor David Sierra

David Sierra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180177634
    Abstract: A comfortable insert comprises a retention structure sized for placement under the eyelids and along at least a portion of conjunctival sac of the upper and lower lids of the eye. The retention structure resists deflection when placed in the conjunctival sac of the eye and to guide the insert along the sac when the eye moves. The retention structure can be configured in many ways to provide the resistance to deflection and may comprise a hoop strength so as to urge the retention structure outward and inhibit movement of the retention structure toward the cornea. The insert may move rotationally with deflection along the conjunctival sac, and may comprise a retention structure having a cross sectional dimension sized to fit within folds of the conjunctiva. The insert may comprise a release mechanism and therapeutic agent to release therapeutic amounts of the therapeutic agent for an extended time.
    Type: Application
    Filed: February 26, 2018
    Publication date: June 28, 2018
    Inventors: Eugene de Juan, JR., Yair Alster, Cary J. Reich, K. Angela Macfarlane, Janelle Chang, Stephen Boyd, David Sierra, Jose D. Alejandro, Douglas Sutton, Alexander J. Gould
  • Patent number: 10004636
    Abstract: A therapeutic system comprises an ocular insert placed on a region outside an optical zone of an eye. The ocular insert comprises two structures: a first skeletal structure and a second cushioning structure. The first structure functions as a skeletal frame which maintains positioning of the implant along the anterior portion of the eye and provides support to the second, cushioning structure. This first structure maintains the attachment of the therapeutic system to the anterior portion of the eye for at least thirty days. In some embodiments the first structure remains a constant size and shape, e.g. a ring shape, a ring with haptics, or a curvilinear ring that is confined to and restrainingly engages the inferior and superior conjunctival fornices so as to retain the implant within the tear fluid and/or against the tissues of the eye.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: June 26, 2018
    Assignee: ForSight Vision5, Inc.
    Inventors: Yair Alster, Eugene de Juan, Jr., Cary J. Reich, Stephen Boyd, David Sierra, Jose D. Alejandro, K. Angela Macfarlane, Douglas Sutton
  • Patent number: 9943401
    Abstract: A therapeutic lens for the treatment of an epithelial defect comprises a layer of therapeutic material disposed over the stroma and/or Bowman's membrane to inhibit water flow from the tear liquid to the stroma and/or Bowman's membrane, such that corneal deturgescence can be restored to decrease corneal swelling and light scattering. The layer may cover and protect nerve fibers to decrease pain. The layer may comprise an index of refraction to inhibit light scatter from an anterior surface of the stroma and/or Bowman's membrane. The lens may comprise a curved anterior surface that provides functional vision for the patient when the epithelium regenerates. The layer of therapeutic material can be positioned on the eye in many ways, for example with a spray that is cured to adhere the layer to the exposed surface of the stroma and/or Bowman's membrane.
    Type: Grant
    Filed: April 6, 2009
    Date of Patent: April 17, 2018
    Inventors: Eugene de Juan, Jr., Cary J. Reich, Stephen Boyd, Yair Alster, David Sierra, Hanson S. Gifford, Jose D. Alejandro, Richard L. Lindstrom, K. Angela Macfarlane, Douglas Sutton, John Anthony Scholl
  • Patent number: 9937073
    Abstract: A comfortable insert comprises a retention structure sized for placement under the eyelids and along at least a portion of conjunctival sac of the upper and lower lids of the eye. The retention structure resists deflection when placed in the conjunctival sac of the eye and to guide the insert along the sac when the eye moves. The retention structure can be configured in many ways to provide the resistance to deflection and may comprise a hoop strength so as to urge the retention structure outward and inhibit movement of the retention structure toward the cornea. The insert may move rotationally with deflection along the conjunctival sac, and may comprise a retention structure having a cross sectional dimension sized to fit within folds of the conjunctiva. The insert may comprise a release mechanism and therapeutic agent to release therapeutic amounts of the therapeutic agent for an extended time.
    Type: Grant
    Filed: January 20, 2015
    Date of Patent: April 10, 2018
    Assignee: ForSight Vision5, Inc.
    Inventors: Eugene de Juan, Jr., Yair Alster, Cary J. Reich, K. Angela Macfarlane, Janelle Chang, Stephen Boyd, David Sierra, Jose D. Alejandro, Douglas Sutton, Alexander J. Gould
  • Publication number: 20170340560
    Abstract: Drug formulations, devices and methods are provided to deliver biologically active substances to the eye. The formulations are delivered into scleral tissues adjacent to or into the suprachoroidal space without damage to the underlying choroid. One class of formulations is provided wherein the formulation is localized in the suprachoroidal space near the region into which it is administered. Another class of formulations is provided wherein the formulation can migrate to another region of the suprachoroidal space, thus allowing an injection in the anterior region of the eye in order to treat the posterior region.
    Type: Application
    Filed: January 4, 2017
    Publication date: November 30, 2017
    Inventors: Ronald YAMAMOTO, Stanley R. CONSTON, David SIERRA
  • Publication number: 20170290702
    Abstract: Drug formulations, devices and methods are provided to deliver biologically active substances to the eye. The formulations are delivered into scleral tissues adjacent to or into the suprachoroidal space without damage to the underlying choroid. One class of formulations is provided wherein the formulation is localized in the suprachoroidal space near the region into which it is administered. Another class of formulations is provided wherein the formulation can migrate to another region of the suprachoroidal space, thus allowing an injection in the anterior region of the eye in order to treat the posterior region.
    Type: Application
    Filed: November 22, 2016
    Publication date: October 12, 2017
    Inventors: Ronald YAMAMOTO, Stanley R. CONSTON, David SIERRA
  • Publication number: 20170056242
    Abstract: A therapeutic system comprises an ocular insert placed on a region outside an optical zone of an eye. The ocular insert comprises two structures: a first skeletal structure and a second cushioning structure. The first structure functions as a skeletal frame which maintains positioning of the implant along the anterior portion of the eye and provides support to the second, cushioning structure. This first structure maintains the attachment of the therapeutic system to the anterior portion of the eye for at least thirty days. In some embodiments the first structure remains a constant size and shape, e.g. a ring shape, a ring with haptics, or a curvilinear ring that is confined to and restrainingly engages the inferior and superior conjunctival fornices so as to retain the implant within the tear fluid and/or against the tissues of the eye.
    Type: Application
    Filed: August 5, 2016
    Publication date: March 2, 2017
    Inventors: Yair Alster, Eugene de Juan, JR., Cary J. Reich, Stephen Boyd, David Sierra, Jose D. Alejandro, K. Angela Macfarlane, Douglas Sutton
  • Publication number: 20160311300
    Abstract: A tailgate cover includes at least one pocket to securely fit over a tailgate. In some embodiments, the tailgate cover includes two or three pockets. The tailgate cover is made of stretchable material such as a stretchable fabric which enables the cover to be stretched securely over the tailgate. To further secure the tailgate cover over the tailgate, any coupling device is able to be used. The tailgate cover is able to include any graphic and/or text.
    Type: Application
    Filed: July 6, 2016
    Publication date: October 27, 2016
    Inventor: David Sierra
  • Patent number: 9474611
    Abstract: The present invention relates to a method for manufacturing an implantable prosthesis, in other words, a biomodel, which can be implanted in a patient, preferably in the cranium of a patient. The method is based on the use of commercially available adhesive tape, in order to reduce the manufacturing costs of said implant since there is no need to heat same to very high temperatures in order to mold the material to be implanted. The implant is preferably made of titanium via a cold-production process, which requires initially supplying a rapid prototype from a CAD model that corresponds to a plastic mold, which is covered with commercially available adhesive tape, in order to obtain another model that makes it possible to form the model that will be transferred to titanium, thus reducing the ideal temperature for molding same.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: October 25, 2016
    Assignee: INDUSTRIAS MEDICAS SAMPEDRO S.A.
    Inventors: Mauricio Toro Restrepo, David Sierra Navaro, Balmore Bedoya Henao
  • Patent number: 9421126
    Abstract: A therapeutic system comprises an ocular insert placed on a region outside an optical zone of an eye. The ocular insert comprises two structures: a first skeletal structure and a second cushioning structure. The first structure functions as a skeletal frame which maintains positioning of the implant along the anterior portion of the eye and provides support to the second, cushioning structure. This first structure maintains the attachment of the therapeutic system to the anterior portion of the eye for at least thirty days. In some embodiments the first structure remains a constant size and shape, e.g. a ring shape, a ring with haptics, or a curvilinear ring that is confined to and restrainingly engages the inferior and superior conjunctival fornices so as to retain the implant within the tear fluid and/or against the tissues of the eye.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: August 23, 2016
    Assignee: ForSight Vision5, Inc.
    Inventors: Yair Alster, Eugene de Juan, Jr., Cary J. Reich, Stephen Boyd, David Sierra, Jose D. Alejandro, K. Angela Macfarlane, Douglas Sutton
  • Patent number: 9412288
    Abstract: A tailgate cover includes at least one pocket to securely fit over a tailgate. In some embodiments, the tailgate cover includes two or three pockets. The tailgate cover is made of stretchable material such as a stretchable fabric which enables the cover to be stretched securely over the tailgate. To further secure the tailgate cover over the tailgate, any coupling device is able to be used. The tailgate cover is able to include any graphic and/or text.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: August 9, 2016
    Inventor: David Sierra
  • Patent number: 9125735
    Abstract: A corneal onlay is configured to adhere to the cornea so as to inhibit epithelial growth under the onlay. Structures can be provided on the onlay to adhere the onlay to the eye. At least one of an epithelial layer or the water inhibiting layer can be provided on or over the onlay, for example a natural epithelial layer or water inhibiting layer that inhibits, for example minimizes, water penetration into the onlay, so as to adhere the onlay to the eye with pumping of the endothelium. The water inhibiting layer may comprise a therapeutic covering positioned over the onlay to inhibit swelling of the cornea. The posterior surface of the onlay may be shaped so as to fit the anterior exposed surface of the cornea.
    Type: Grant
    Filed: October 4, 2010
    Date of Patent: September 8, 2015
    Assignee: Forsight Labs, LLC
    Inventors: Eugene de Juan, Jr., Cary J. Reich, Stephen Boyd, David Sierra, Jose D. Alejandro
  • Publication number: 20150179092
    Abstract: A tailgate cover includes at least one pocket to securely fit over a tailgate. In some embodiments, the tailgate cover includes two or three pockets. The tailgate cover is made of stretchable material such as a stretchable fabric which enables the cover to be stretched securely over the tailgate. To further secure the tailgate cover over the tailgate, any coupling device is able to be used. The tailgate cover is able to include any graphic and/or text.
    Type: Application
    Filed: March 3, 2015
    Publication date: June 25, 2015
    Inventor: David Sierra
  • Publication number: 20150133878
    Abstract: A comfortable insert comprises a retention structure sized for placement under the eyelids and along at least a portion of conjunctival sac of the upper and lower lids of the eye. The retention structure resists deflection when placed in the conjunctival sac of the eye and to guide the insert along the sac when the eye moves. The retention structure can be configured in many ways to provide the resistance to deflection and may comprise a hoop strength so as to urge the retention structure outward and inhibit movement of the retention structure toward the cornea. The insert may move rotationally with deflection along the conjunctival sac, and may comprise a retention structure having a cross sectional dimension sized to fit within folds of the conjunctiva. The insert may comprise a release mechanism and therapeutic agent to release therapeutic amounts of the therapeutic agent for an extended time.
    Type: Application
    Filed: January 20, 2015
    Publication date: May 14, 2015
    Applicant: ForSight Vision5, Inc.
    Inventors: Eugene de Juan, JR., Yair Alster, Cary J. Reich, K. Angela MacFarlane, Janelle Chang, Stephen Boyd, David Sierra, Jose D. Alejandro, Douglas Sutton, Alexander J. Gould
  • Patent number: 8998288
    Abstract: A tailgate cover includes at least one pocket to securely fit over a tailgate. In some embodiments, the tailgate cover includes two or three pockets. The tailgate cover is made of stretchable material such as a stretchable fabric which enables the cover to be stretched securely over the tailgate. To further secure the tailgate cover over the tailgate, any coupling device is able to be used. The tailgate cover is able to include any graphic and/or text.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: April 7, 2015
    Inventor: David Sierra
  • Patent number: 8939948
    Abstract: A comfortable insert comprises a retention structure sized for placement under the eyelids and along at least a portion of conjunctival sac of the upper and lower lids of the eye. The retention structure resists deflection when placed in the conjunctival sac of the eye and to guide the insert along the sac when the eye moves. The retention structure can be configured in many ways to provide the resistance to deflection and may comprise a hoop strength so as to urge the retention structure outward and inhibit movement of the retention structure toward the cornea. The insert may move rotationally with deflection along the conjunctival sac, and may comprise a retention structure having a cross sectional dimension sized to fit within folds of the conjunctiva. The insert may comprise a release mechanism and therapeutic agent to release therapeutic amounts of the therapeutic agent for an extended time.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: January 27, 2015
    Assignee: ForSight Vision5, Inc.
    Inventors: Eugene de Juan, Jr., Yair Alster, Cary J. Reich, K. Angela MacFarlane, Janelle Chang, Stephen Boyd, David Sierra, Jose D. Alejandro, Douglas Sutton, Alexander J. Gould
  • Publication number: 20150018949
    Abstract: The present invention relates to a method for manufacturing an implantable prosthesis, in other words, a biomodel, which can be implanted in a patient, preferably in the cranium of a patient. The method is based on the use of commercially available adhesive tape, in order to reduce the manufacturing costs of said implant since there is no need to heat same to very high temperatures in order to mold the material to be implanted. The implant is preferably made of titanium via a cold-production process, which requires initially supplying a rapid prototype from a CAD model that corresponds to a plastic mold, which is covered with commercially available adhesive tape, in order to obtain another model that makes it possible to form the model that will be transferred to titanium, thus reducing the ideal temperature for molding same.
    Type: Application
    Filed: December 14, 2011
    Publication date: January 15, 2015
    Applicant: INDUSTRIAS MEDICAS SAMPEDRO S.A.
    Inventors: Mauricio Toro Restrepo, David Sierra Navaro, Balmore Bedoya Henao
  • Publication number: 20140054922
    Abstract: A tailgate cover includes at least one pocket to securely fit over a tailgate. In some embodiments, the tailgate cover includes two or three pockets. The tailgate cover is made of stretchable material such as a stretchable fabric which enables the cover to be stretched securely over the tailgate. To further secure the tailgate cover over the tailgate, any coupling device is able to be used. The tailgate cover is able to include any graphic and/or text.
    Type: Application
    Filed: November 5, 2013
    Publication date: February 27, 2014
    Inventor: David Sierra
  • Patent number: 8602481
    Abstract: A tailgate cover includes at least one pocket to securely fit over a tailgate. In some embodiments, the tailgate cover includes two or three pockets. The tailgate cover is made of stretchable material such as a stretchable fabric which enables the cover to be stretched securely over the tailgate. To further secure the tailgate cover over the tailgate, any coupling device is able to be used. The tailgate cover is able to include any graphic and/or text.
    Type: Grant
    Filed: January 17, 2013
    Date of Patent: December 10, 2013
    Inventor: David Sierra
  • Patent number: 8555416
    Abstract: Gloves for forming a figure are designed to represent a figure such as an animal with one glove forming a first portion of the figure and a second glove forming a second portion of the figure. For example, for a pair of shark gloves, one glove is the top of the shark's mouth with upper teeth and the second glove is the bottom of the shark's mouth with lower teeth. When worn by a user, the user is able to move the two gloves in an open and closed motion so that the shark appears to be opening and biting down. The gloves provide entertainment as well as motivation for the fans and players.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: October 15, 2013
    Inventor: David Sierra