Patents by Inventor David Simon Millan
David Simon Millan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11773085Abstract: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as cancers and viral infections.Type: GrantFiled: July 29, 2020Date of Patent: October 3, 2023Assignee: Foghorn Therapeutics Inc.Inventors: Qianhe Zhou, Michael Bocker, David Simon Millan, Ho Man Chan, Luis Soares, Matthew Russell Netherton, Sabine K. Ruppel, Zhaoxia Yang, Jason T. Lowe, Francois Brucelle
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Publication number: 20230149414Abstract: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.Type: ApplicationFiled: January 29, 2021Publication date: May 18, 2023Inventors: Neville John ANTHONY, Rishi G. VASWANI, David Simon MILLAN, Shawn E.R. SCHILLER, Kevin J. WILSON
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Publication number: 20230138480Abstract: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.Type: ApplicationFiled: October 13, 2022Publication date: May 4, 2023Inventors: Neville John ANTHONY, David Simon MILLAN, Rishi G. VASWANI, Shawn E.R. SCHILLER
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Publication number: 20230079819Abstract: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.Type: ApplicationFiled: January 29, 2020Publication date: March 16, 2023Inventors: Rishi G. VASWANI, Neville John ANTHONY, David Simon MILLAN, Shawn E.R. SCHILLER, Kevin J. WILSON, David S. HUANG
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Patent number: 11497752Abstract: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.Type: GrantFiled: January 29, 2019Date of Patent: November 15, 2022Assignee: Foghorn Therapeutics Inc.Inventors: Neville John Anthony, David Simon Millan, Rishi G. Vaswani, Shawn E. R. Schiller
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Publication number: 20220119378Abstract: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.Type: ApplicationFiled: January 29, 2020Publication date: April 21, 2022Inventors: Neville John ANTHONY, Rishi G. VASWANI, David Simon MILLAN, Shawn E.R. SCHILLER
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Publication number: 20210038611Abstract: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.Type: ApplicationFiled: January 29, 2019Publication date: February 11, 2021Inventors: Neville John ANTHONY, David Simon MILLAN, Rishi G. VASWANI, Shawn E.R. SCHILLER
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Publication number: 20210009568Abstract: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as cancers and viral infections.Type: ApplicationFiled: July 29, 2020Publication date: January 14, 2021Inventors: Qianhe Zhou, Michael Bocker, David Simon Millan, Ho Man Chan, Luis Soares, Matthew Russell Netherton, Sabine K. Ruppel, Zhaoxia Yang, Jason T. Lowe, Francois Brucelle
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Publication number: 20150291514Abstract: The present invention relates to sulfonamide derivatives of formula (I): or a pharmaceutically acceptable salts thereof, wherein Z, R1a, R1b, R2, R3, R4 and R5 are as defined in the description, and to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. The compounds of formula (I) are Nav1.7 inhibitors useful in the treatment of a wide range of disorders, particularly pain.Type: ApplicationFiled: December 21, 2012Publication date: October 15, 2015Applicant: PFIZER LIMTEDInventors: Alan Daniel Brown, Sebastien Rene Gabriel Galan, David Simon Millan, David James Rawson, Robert Ian Storer, Paul Anthony Stupple, NIgel Alan Swain
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Patent number: 9096558Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to new sulfonamide Nav1.7 inhibitors of formula (I) or pharmaceutically acceptable salts thereof, wherein X, Y1, Y2, Z, R1, R2 and R3 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.Type: GrantFiled: July 1, 2011Date of Patent: August 4, 2015Assignees: Pfizer Limited, Icagen, Inc.Inventors: Benjamin Scott Greener, Brian Edward Marron, David Simon Millan, David James Rawson, Robert Ian Storer, Nigel Alan Swain
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Patent number: 8907101Abstract: The present invention relates to compounds of the formula and pharmaceutically acceptable salts, solvates or tautomers thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds, and the uses of such compounds, in particular for the treatment of pain.Type: GrantFiled: August 16, 2013Date of Patent: December 9, 2014Assignees: Pfizer Limited, Icagen, Inc.Inventors: Serge Beaudoin, Michael Christopher Laufersweiler, Christopher John Markworth, Brian Edward Marron, David Simon Millan, David James Rawson, Steven Michael Reister, Kosuke Sasaki, Robert Ian Storer, Paul Anthony Stupple, Nigel Alan Swain, Christopher William West, Shulan Zhou
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Publication number: 20140336160Abstract: This invention relates to novel glucocorticoid receptor agonists of formula (I): and to processes and intermediates for their preparation. The present invention also relates to pharmaceutical compositions containing these compounds, to their combination with one or more other therapeutic agents, as well as to their use for the treatment of a number of inflammatory and allergic diseases, disorders and conditions.Type: ApplicationFiled: July 23, 2014Publication date: November 13, 2014Inventors: Paul Alan Glossop, David Simon Millan, David Anthony Price
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Patent number: 8822439Abstract: This invention relates to novel glucocorticoid receptor agonists of formula (I): and to processes and intermediates for their preparation. The present invention also relates to pharmaceutical compositions containing these compounds, to their combination with one or more other therapeutic agents, as well as to their use for the treatment of a number of inflammatory and allergic diseases, disorders and conditions.Type: GrantFiled: November 24, 2008Date of Patent: September 2, 2014Assignee: Pfizer Inc.Inventors: Paul Alan Glossop, David Simon Millan, David Anthony Price
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Patent number: 8685977Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein Ar1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.Type: GrantFiled: July 11, 2011Date of Patent: April 1, 2014Assignee: Pfizer LimitedInventors: Andrew Simon Bell, Alan Daniel Brown, Russell Andrew Lewthwaite, Ian Roger Marsh, David Simon Millan, Manuel Perez Pacheco, David James Rawson, Nunzio Sciammetta, Robert Ian Storer, Paul Anthony Stupple, Nigel Alan Swain, Marcel John De Groot
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Publication number: 20130338111Abstract: The present invention relates to compounds of the formula and pharmaceutically acceptable salts, solvates or tautomers thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds, and the uses of such compounds, in particular for the treatment of pain.Type: ApplicationFiled: August 16, 2013Publication date: December 19, 2013Applicants: Icagen, Inc., Pfizer LimitedInventors: Serge Beaudoin, Michael Christopher Laufersweiler, Christopher John Markworth, Brian Edward Marron, David Simon Millan, David James Rawson, Steven Michael Reister, Kosuke Sasaki, Robert Ian Storer, Paul Anthony Stupple, Nigel Alan Swain, Christopher William West, Shulan Zhou
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Patent number: 8592629Abstract: This invention relates to sulfonamide derivative of formula (I), to their use in medicine, to compositions containing them, to processes for their preparation, and to intermediates used in such processes. These compounds are inhibitors of Nav1.7.Type: GrantFiled: July 11, 2011Date of Patent: November 26, 2013Assignee: Pfizer LimitedInventors: Andrew Simon Bell, Alan Daniel Brown, Marcel John De Groot, Russell Andrew Lewthwaite, Ian Roger Marsh, David Simon Millan, Manuel Perez Pacheco, David James Rawson, Nunzio Sciammetta, Robert Ian Storer, Nigel Alan Swain, Steven Matthieu Gaulier
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Patent number: 8541588Abstract: The present invention relates to compounds of the formula and pharmaceutically acceptable salts, solvates or tautomers thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds, and the uses of such compounds, in particular for the treatment of pain.Type: GrantFiled: February 20, 2012Date of Patent: September 24, 2013Assignees: Pfizer Limited, Icagen, Inc.Inventors: Serge Beaudoin, Michael Christopher Laufersweiler, Christopher John Markworth, Brian Edward Marron, David Simon Millan, David James Rawson, Steven Michael Reister, Kosuke Sasaki, Robert Ian Storer, Paul Anthony Stupple, Nigel Alan Swain, Christopher William West, Shulan Zhou
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Publication number: 20130109696Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to new sulfonamide Nav1.7 inhibitors of formula (I) or pharmaceutically acceptable salts thereof, wherein X, Y1, Y2, Z, R1, R2 and R3 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.Type: ApplicationFiled: July 1, 2011Publication date: May 2, 2013Applicant: Pfizer LimitedInventors: Benjamin Scott Greener, Brian Edward Marron, David Simon Millan, David James Rawson, Robert Ian Storer, Nigel Alan Swain
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Publication number: 20120149679Abstract: The present invention relates to compounds of the formula and pharmaceutically acceptable salts, solvates or tautomers thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds, and the uses of such compounds, in particular for the treatment of pain.Type: ApplicationFiled: February 20, 2012Publication date: June 14, 2012Inventors: Serge Beaudoin, Michael Christopher Laufersweiler, Christopher John Markworth, Brian Edward Marron, David Simon Millan, David James Rawson, Steven Michael Reister, Kosuke Sasaki, Robert Ian Storer, Paul Anthony Stupple, Nigel Alan Swain, Christopher William West, Shulan Zhou
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Patent number: 8153814Abstract: The present invention relates to compounds of the formula and pharmaceutically acceptable salts, solvates or tautomers thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds, and the uses of such compounds, in particular for the treatment of pain.Type: GrantFiled: January 12, 2010Date of Patent: April 10, 2012Assignees: Pfizer Limited, Icagen, Inc.Inventors: Serge Beaudoin, Michael Christopher Laufersweiler, Christopher John Markworth, Brian Edward Marron, David Simon Millan, David James Rawson, Steven Michael Reister, Kosuke Sasaki, Robert Ian Storer, Paul Anthony Stupple, Nigel Alan Swain, Christopher William West, Shulan Zhou