Abstract: A method for tone mapping a high dynamic range image of a large terrestrial area into a lower dynamic range image uses a globally aware, locally adaptive approach whereby local tonal balancing parameter values are derived from known tone mapping parameters for a local 3×3 matrix of image tiles and used in turn to derive a local sigmoid transfer function for pixels in the tile in the middle of the matrix. A global sigmoid transfer function is derived based on values of the tone mapping parameters applicable to the entire image. A lower dynamic range image pixel will have a local tone mapped value and a globally tone mapped value, which are combined by giving each a weighted value to provide a final low dynamitic range pixel value.

Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein Ar1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.

Abstract: A method and apparatus for optimizing a computer assisted procedure is provided. A method and apparatus for performing a procedure is also provided. Data can be accessed and processed to optimize and perform a procedure. The data can be augmented or supplemented with patient specific data.

Abstract: A mobile retail store structure transportable to a plurality of different locations includes a trailer construction configured both exteriorly and interiorly for housing a plurality of storage bins wherein products and/or parts can be stored. Each trailer is a self-sufficient module which includes doors at one end of the trailer unit for entry and exit thereto, portable stairs for providing access to the entry doors, opposed side doors and associated walkways for allowing coupling to additional similarly constructed trailers, extendable canopies for providing a secure passageway between the respective coupled trailers, and a generator/HVAC system for providing heating, cooling and electrical power to each trailer unit. In one embodiment, a terminal is provided to allow a user to either browse electronically various items for selection and/or sale, or access a self-service check-out station to complete a transaction.

Abstract: A correlation confocal microscope uses correlated photon pairs to improve resolution. It employs a source of a light beam converging to a point location on a sample, and an objective that gathers light from the point location and generates an image beam. A modulator applies a spatial pattern of modulation to the source light beam to define spatially correlated photons whose spatial correlations are preserved in modulated light gathered from the sample. A filter applies a modulation-selective filter function to the image light beam to generate a filtered light beam of like-modulated photons. A coincidence detector detects temporally coincident photon pairs in the filtered light beam, generating a pulse output that indicates the magnitude of a light-detectable property (such as transmissivity or reflectivity) of the sample at the point location. The modulator may apply phase modulation and the filter may be a phase-sensitive component such as an interferometer.

Abstract: Disclosed herein is an LED-based light for replacing a fluorescent bulb in a conventional fluorescent light fixture. The LED-based light includes a housing having a first end opposing a second end, a circuit board disposed within the housing and extending along a longitudinal axis of the housing, at least one LED mounted to the circuit board, at least one end cap disposed on one of the first and second ends of the housing, the end cap including a switch and at least one electrically conductive pin configured for physical and electrical connection to the light fixture; and circuitry configured to provide a current path between the at least one LED and the at least one electrically conductive pin, wherein the switch is configured to selectively disconnect the current path.

Abstract: The present invention relates to compounds of the formula and pharmaceutically acceptable salts, solvates or tautomers thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds, and the uses of such compounds, in particular for the treatment of pain.

Abstract: A method is provided for taking electrical impedance tomography measurements using multiple electrodes located at selected positions external to a volume of a subject body. Multiple orthogonal or near-orthogonal signals are introduced simultaneously by way of selected different electrodes and resultant predetermined responses (if any) at receiving electrodes are recorded or determined. The signals are encoded using the technique of code division multiplexing and received signals at each receiving electrode are cross-correlated with original signals to determine the contribution of each original signal to a composite received signal. The invention also relates to apparatus suitable for use in applying a method.

Abstract: This invention relates to sulfonamide derivative of formula (I), to their use in medicine, to compositions containing them, to processes for their preparation, and to intermediates used in such processes. These compounds are inhibitors of Nav1.7.

Abstract: Approaches are disclosed for electrical impedance tomography which apply a current to a region at two or more frequencies and acquire voltage measurements at each frequency to generate a set of multi-frequency voltage measurements. One or more images of the region are generated, using spectral constraints, based on the multi-frequency data.

Abstract: A method for manufacturing a lightweight structural trim part is comprising the following steps: (A) inserting a plurality of layers into a molding tool comprising a first molding half (6) and a second molding half (7). The second molding half (7) comprises a plurality of cup-like indentation (8). The plurality of layers at least comprises a first air permeable skin layer (1) facing the first molding half (6), a second air tight skin layer (3,4) facing the second molding half (7), and a film layer (2) between the two skin layers. (B) Closing the molding tool and discharging gas from one side in order to press the first skin layer against the first molding half. (C) Shaping and consolidating the first porous skin layer. (D) Charging with pressurized air the first space in order to press the second skin layer against the second molding half. (E) Shaping and consolidating the second skin layer.

Abstract: The present invention relates to compounds of the formula and pharmaceutically acceptable salts, solvates or tautomers thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds, and the uses of such compounds, in particular for the treatment of pain.

Abstract: A UV-IR combination curing system and method for manufacture and repair of composite parts, such as for use in wind blade manufacture and repair. The system and method utilize UV and IR dual radiation sources to cure glass fiber reinforced laminates containing a photo initiator. The UV and IR dual radiation sources can be configured as discrete stand-alone UV and IR lamps used in a side by side configuration, a plurality of UV lamps with thermal IR radiation, a combined UV/IR lamp, or other forms of light sources providing both UV and IR radiation. To achieve high glass transition and complete curing of thick laminates, the IR radiation source is initially turned on to heat the laminate to close to 40° C.-100° C. before the UV radiation source is turned on. The IR radiation source can be turned off after UV radiation source is activated.

Abstract: Disclosed herein is an LED-based light for replacing a fluorescent bulb in a conventional fluorescent light fixture. The LED-based light includes a housing having a first end opposing a second end, a circuit board disposed within the housing and extending along a longitudinal axis of the housing, at least one LED mounted to the circuit board, at least one end cap disposed on one of the first and second ends of the housing, the end cap including a switch and at least one electrically conductive pin configured for physical and electrical connection to the light fixture; and circuitry configured to provide a current path between the at least one LED and the at least one electrically conductive pin, wherein the switch is configured to selectively disconnect the current path.

Abstract: One or more markers or sensors are positioned in the vasculature of a patient to facilitate determining the location, configuration, and/or orientation of a vessel or certain aspects thereof (e.g., a branch vessel), determining the location, configuration and/or orientation of a endovascular devices prior to and during prosthesis deployment as well as the relative position of portions of the vasculature and devices, generating an image of a virtual model of a portion of one or more vessels (e.g., branch vessels) or devices, and/or formation of one or more openings in a tubular prosthesis in situ to allow branch vessel perfusion when the prosthesis is placed over one or more branch vessels in a patient (e.g., when an aortic abdominal artery stent-graft is fixed to the aorta superior to the renal artery ostia).

Abstract: Disclosed herein are embodiments of a LED fluorescent tube replacement lamp and lighting modules from which the lamp is constructed. One embodiment of a replacement lamp includes a plurality of interchangeable lighting modules that are configured to be electrically connected to adjacent modules. The interchangeable lighting modules can include end modules each having an end cap with pin connectors, at least one of the end modules includes electrical circuitry connected to the pin connectors for powering the modules. The lighting modules can also be center unit modules having LEDs mounted to a circuit board. The replacement lamps can be made from conceivable configurations of the lighting modules, requiring removal of only one module for repair or replacement.

Abstract: Methods, systems, and techniques that enable enhanced coordination and management of a plurality of servers cooperatively operating in a cluster of servers. In one implementation, a plurality of enhanced Virtual Desktop Management (VDM) Servers operating in a Federated Virtual Desktop Management (VDM) Cluster are provided. Each of the enhanced VDM Servers active in the Federated VDM Cluster use federated task information pertaining to and derived from various executing federated tasks. However, only a single selected one of the plurality of enhanced VDM Servers is executing a particular one of the federated tasks at a time so that each federated task is continuously running somewhere in the Federated VDM Cluster.

Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to new sulfonamide Nav1.7 inhibitors of formula (I) or pharmaceutically acceptable salts thereof, wherein X, Y1, Y2, Z, R1, R2 and R3 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.

Abstract: A non-transitory computer readable storage medium includes executable instructions to evaluate a web page to derive a web page scoring schema that is contingent upon selected advertising campaign parameters that establish a unique scoring system of an advertiser. A bid on an advertisement opportunity in the web page based is generated based upon the web page scoring schema.