Patents by Inventor David Simon

David Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210047365
    Abstract: Methods and systems for control of solid phase peptide synthesis are generally described. Control of solid phase peptide synthesis involves the use of feedback from one or more reactions and/or processes (e.g., reagent removal) taking place in the solid phase peptide synthesis system. In some embodiments, a detector may detect one or more fluids flowing across a detection zone of a solid phase peptide synthesis system and one or more signals may be generated corresponding to the fluid(s). For instance, an electromagnetic radiation detector positioned downstream of a reactor may detect a fluid exiting the reactor after a deprotection reactor and produce a signal(s). In some embodiments, based at least in part on information derived from the signal(s), a parameter of the system may be modulated prior to and/or during one or more subsequent reactions and/or processes taking place in the solid phase peptide synthesis system.
    Type: Application
    Filed: May 15, 2020
    Publication date: February 18, 2021
    Applicant: Massachusetts Institute of Technology
    Inventors: Dale Arlington Thomas, Alexander James Mijalis, Bradley L. Pentelute, Mark David Simon, Surin Mong
  • Patent number: 10920798
    Abstract: The invention relates to a hydraulic circuit (10) for an aircraft turboprop comprising a hydraulic fluid tank (16), a pump (14), a component (12) that is supplied with fluid pressurised by the pump (14) and that is selectively put into operation, and a fluid recirculation circuit (20) between the pump discharge (14) and the tank (16) characterised in that it comprises a valve (22) located in the recirculation circuit (20), that is capable of closing the recirculation circuit (20) when the component (12) is not in operation and is capable of opening the recirculation circuit (20) when the component is in operation.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: February 16, 2021
    Assignee: SAFRAN AIRCRAFT ENGINES
    Inventors: Benjamin André Goguet-Chapuis, David Simon
  • Publication number: 20210038611
    Abstract: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.
    Type: Application
    Filed: January 29, 2019
    Publication date: February 11, 2021
    Inventors: Neville John ANTHONY, David Simon MILLAN, Rishi G. VASWANI, Shawn E.R. SCHILLER
  • Publication number: 20210044353
    Abstract: Devices, systems and methods for encoding information using optical components are described. Information associated with a first optical signal (e.g., an optical pump) is encoded onto the phase of a second optical signal (e.g., an optical probe) using cross phase modulation (XPM) in a non-linear optical medium. The optical signals are multiplexed together into the nonlinear optical medium. The probe experiences a modified index of refraction as it propagates through the medium and thus accumulates a phase change proportional to the intensity of the pump. The disclosed devices can be incorporated into larger components and systems for various applications such as scientific diagnostics, radar, remote sensing, wireless communications, and quantum computing that can benefit from encoding and generation of low noise, high resolution signals.
    Type: Application
    Filed: April 10, 2020
    Publication date: February 11, 2021
    Inventors: Brandon Walter Buckley, David Simon Perlmutter, Peter Thomas Setsuda DeVore, Apurva Shantharaj Gowda, Jason Thomas Chou
  • Patent number: 10903389
    Abstract: Presented herein are reactors for growing or depositing semiconductor films or devices. The reactors disclosed may be used for the production of III-V materials grown by hydride vapor phase epitaxy (HVPE).
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: January 26, 2021
    Assignee: Alliance for Sustainable Energy, LLC
    Inventors: Kevin Louis Schulte, Aaron Joseph Ptak, John David Simon
  • Publication number: 20210018814
    Abstract: Devices, methods and systems for generating wideband, high-fidelity arbitrary radio frequency (RF) passband signals are described. A voltage tunable optical filter for arbitrary RF passband signal generation includes a first input configured to receive a broadband optical pulse train, a second input configured to receive a first control voltage representative of an amplitude signal, an electrooptic modulator to receive the broadband optical pulse train and the first control voltage, to modulate the broadband optical pulse train in accordance with the amplitude signal, and to produce two complementary optical outputs that form two arms of an interferometer, an optical delay component to impart an optical path difference into one of the complementary outputs of the electrooptic modulator, and a combiner or a splitter to receive two complementary optical outputs of the electrooptic modulator after impartation of the optical path difference and to produce an output interference pattern of fringes.
    Type: Application
    Filed: January 24, 2020
    Publication date: January 21, 2021
    Inventors: Apurva Shantharaj Gowda, Jacky Chak-Kee Chan, Peter Thomas Setsuda DeVore, David Simon Perlmutter, Jason Thomas Chou
  • Publication number: 20210021337
    Abstract: Methods, devices and systems for providing accurate measurements of timing errors using optical techniques are described. An example timing measurement device includes an optical hybrid that receives two optical pulse trains and produces two or more phase shifted optical outputs. The timing measurement device further includes two or more optical filters that receive the outputs of the optical hybrid to produce multiple pulse signals with distinctive frequency bands. The device also includes one or more photodetectors and analog-to-digital converters to receive to produce electrical signals in the digital domain corresponding to the optical outputs of the hybrid. A timing error associated with the optical pulse trains can be determined using the electrical signals in digital domain based on a computed phase difference between a first frequency band signal and a second frequency band signal and a computed frequency difference between the first frequency band signal and the second frequency band.
    Type: Application
    Filed: June 10, 2020
    Publication date: January 21, 2021
    Inventors: Peter Thomas Setsuda DeVore, Apurva Shantharaj Gowda, David Simon Perlmutter, Joshua Linne Olson, Jason Thomas Chou
  • Publication number: 20210021349
    Abstract: Devices, methods for analog-to-digital converters (ADCs) that perform high-dynamic range measurements based on optical techniques are disclosed. In one example aspect, an optical encoder includes a polarization rotator configured to receive a train of optical pulses, and an electro-optic (EO) modulator coupled to an output of the polarization rotator. The EO modulator is configured to receive a radio frequency (RF) signal and to produce a phase modulated signal in accordance with the RF signal. The optical encoder also includes a polarizing beam splitter coupled to the output of the EO modulator; and an optical hybrid configured to receive two optical signals from the polarizing beam splitter and to produce four optical outputs that are each phase shifted with respect to one another.
    Type: Application
    Filed: May 11, 2020
    Publication date: January 21, 2021
    Inventors: Peter Thomas Setsuda DeVore, Apurva Shantharaj Gowda, David Simon Perlmutter, Alexander Thomas Wargo, Jason Thomas Chou
  • Publication number: 20210021914
    Abstract: Device, methods and systems for the electronic demodulation of optically phase demodulated signals are described. An example optical local oscillator generator configured to generate a radio frequency (RF) tone at a desired RF frequency includes a first input configured to receive a broadband optical pulse train, a second input coupled to a delay line interferometer to receive a first control voltage for controlling a delay value of the interferometer and to produce an output optical pulse train, a dispersive element, coupled to the delay line interferometer, to map the output optical pulse train to a time-domain modulated optical pulse train, an optical-to-electrical converter, coupled to the dispersive element, to convert the time-domain modulated optical pulse train to an analog electrical signal, and an RF filter, coupled to the optical-to-electrical converter, to filter the analog electrical signal to generate the RF tone at the desired RF frequency.
    Type: Application
    Filed: May 7, 2020
    Publication date: January 21, 2021
    Inventors: David Simon Perlmutter, Peter Thomas Setsuda DeVore, Apurva Shantharaj Gowda, Jason Thomas Chou
  • Publication number: 20210009568
    Abstract: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as cancers and viral infections.
    Type: Application
    Filed: July 29, 2020
    Publication date: January 14, 2021
    Inventors: Qianhe Zhou, Michael Bocker, David Simon Millan, Ho Man Chan, Luis Soares, Matthew Russell Netherton, Sabine K. Ruppel, Zhaoxia Yang, Jason T. Lowe, Francois Brucelle
  • Patent number: 10889613
    Abstract: Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: January 12, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Mark David Simon, Bradley L. Pentelute, Andrea Adamo, Patrick Louis Heider, Klavs F. Jensen
  • Publication number: 20200407873
    Abstract: Disclosed herein are methods and devices that use a low-thermal conductivity inert gas to shield reactant gases and thus enabling a cold wall operation within a hot wall system.
    Type: Application
    Filed: June 13, 2020
    Publication date: December 31, 2020
    Inventors: Elisabeth Lynne MCCLURE, Kevin Louis SCHULTE, Aaron Joseph PTAK, John David SIMON, Wondwosen Tilahun METAFERIA
  • Publication number: 20200400049
    Abstract: Methods and systems are provided for a lubricant system for an engine. In one example, the system includes external delivery lines coupling an oil reservoir of the engine to a plurality of cylinder head oil galleries, the engine also having internal oil passages. An amount of hydraulic fluid delivered via the external delivery lines is controlled by a pressure control valve having a vent line.
    Type: Application
    Filed: June 19, 2019
    Publication date: December 24, 2020
    Inventors: Abhijyoth Vempati, David Simon
  • Publication number: 20200398755
    Abstract: An external rearview device for a motor vehicle includes a base assembly provided for arrangement on the motor vehicle; a head assembly configured to be attached to the base assembly; rearview means including at least one of a camera unit and a reflective element secured within the head assembly, the head assembly configured to be detachable and selected from a set comprising a first head assembly with a first rearview means including at least one reflective element and a second head assembly with a second rearview means including at least one reflective element, and a camera unit configured to obtain a rearview image through the reflective element, and a third head assembly with a third rearview means including the camera unit.
    Type: Application
    Filed: October 31, 2018
    Publication date: December 24, 2020
    Inventors: Andrew Lettis, Graham Rehill, Callum Scott-Collins, Andreas Herrmann, Arne Schmierer, David Simon Field, Francis Charlet
  • Patent number: 10871090
    Abstract: Methods and systems are provided for a lubricant system for an engine. In one example, the system includes external delivery lines coupling an oil reservoir of the engine to a plurality of cylinder head oil galleries, the engine also having internal oil passages. An amount of hydraulic fluid delivered via the external delivery lines is controlled by a pressure control valve having a vent line.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: December 22, 2020
    Assignee: Ford Global Technologies, LLC
    Inventors: Abhijyoth Vempati, David Simon
  • Publication number: 20200392645
    Abstract: Disclosed herein are novel hydride vapor phase epitaxy reactors and methods of use.
    Type: Application
    Filed: June 15, 2020
    Publication date: December 17, 2020
    Inventors: Kevin Louis SCHULTE, Aaron Joseph PTAK, John David SIMON
  • Patent number: 10783691
    Abstract: Certain embodiments involve generating one or more of appearance guide and a positional guide and using one or more of the guides to synthesize a stylized image or animation. For example, a system obtains data indicating a target image and a style exemplar image. The system generates an appearance guide, a positional guide, or both from the target image and the style exemplar image. The system uses one or more of the guides to transfer a texture or style from the style exemplar image to the target image.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: September 22, 2020
    Assignees: ADOBE INC., CZECH TECHNICAL UNIVERSITY IN PRAGUE
    Inventors: David Simons, Michal Lukac, Daniel Sykora, Elya Shechtman, Paul Asente, Jingwan Lu, Jakub Fiser, Ondrej Jamriska
  • Publication number: 20200294495
    Abstract: Disclosed systems and methods predict visemes from an audio sequence. In an example, a viseme-generation application accesses a first audio sequence that is mapped to a sequence of visemes. The first audio sequence has a first length and represents phonemes. The application adjusts a second length of a second audio sequence such that the second length equals the first length and represents the phonemes. The application adjusts the sequence of visemes to the second audio sequence such that phonemes in the second audio sequence correspond to the phonemes in the first audio sequence. The application trains a machine-learning model with the second audio sequence and the sequence of visemes. The machine-learning model predicts an additional sequence of visemes based on an additional sequence of audio.
    Type: Application
    Filed: May 29, 2020
    Publication date: September 17, 2020
    Inventors: Wilmot Li, Jovan Popovic, Deepali Aneja, David Simons
  • Patent number: 10749052
    Abstract: Methods for forming interdigitated back contact solar cells from III-V materials are provided. According to an aspect of the invention, a method includes depositing a patterned Zn layer to cover first areas of an n-type emitter region, wherein the emitter region comprises a III-V material, and forming a passivated back contact region by counter-doping the first areas of the emitter region by diffusing Zn from the patterned Zn layer into the first areas of the emitter region, such that the first areas of the emitter region become p-type.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: August 18, 2020
    Assignee: Alliance for Sustainable Energy, LLC
    Inventors: David Levi Young, Myles Aaron Steiner, John David Simon
  • Patent number: 10700534
    Abstract: The uneven charge and discharge from non-collocated batteries within an HMD can be solved by monitoring the DC current on the paths coupled to the first battery and the second battery and making an adjustment in the path resistance to equalize, or at least reduce, the difference between the currents on the two paths. Aspects of the technology described herein monitor current on paths from two or more non-collocated batteries. When the currents are different, resistance is dynamically added to the path with the higher current to equalize the current in the two paths. The monitoring and resistance adjustment can occur during discharge from a battery to a load and during battery recharge.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: June 30, 2020
    Assignee: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Julian Arlo Binder, David Paul Wunsch Desrosiers, Eugene Lvovich Shoykhet, David Simon Lukofsky, Agustya Ruchir Mehta, Junius Mark Penny