Abstract: A vehicle parking management system includes one or more processors configured to receive data indicative of one or more characteristics of one or more parking locations. The one or more processors is also configured to determine one or more recommended parking locations of the one or more parking locations based on the data and based on an input related to a vehicle. The one or more processors is further configured to output a recommendation of the one or more recommended parking locations via a display screen to a driver of the vehicle.

Abstract: A device and computer program product including one or more processors and a memory coupled to the one or more processors. The device being configured to selectively run in a timing testing mode or in a mode of operation other than the timing testing mode, wherein in the timing testing mode the device is configured to attempt to induce skew.

Abstract: One or more aspects of the present disclosure are directed to network optimization solutions provided as software agents (applications) executed on network nodes in a heterogenous multi-vendor environment to provide cross-layer network optimization and ensure availability of network resources to meet associated Quality of Experience (QoE) and Quality of Service (QoS). In one aspect, a network slicing engine is configured to receive at least one request from at least one network endpoint for access to the heterogeneous multi-vendor network for data transmission; receive information on state of operation of a plurality of communication links between the plurality of nodes; determine a set of data transmission routes for the request; assign a network slice for serving the request; determine, from the set of data transmission routes, an end-to-end route for the network slice; and send network traffic associated with the request using the network slice and over the end-to-end route.

Abstract: A liquid chromatography sample manager includes a thermal chamber, a sample platter mounted in the thermal chamber, and a needle drive including a base having a shaft configured to rotate about a vertical axis, the base attachable to an interior of a sample manager of a liquid chromatography system. The needle drive further includes a needle assembly attached to the base, the needle assembly including a sample needle, and a drive system attached to the base, the drive system including a sample needle motor configured to impart vertical movement of the sample needle. The liquid chromatography sample manager further includes a sample delivery system configured to transfer a first sample from a first sample vial carrier located in the sample platter into a chromatographic flow stream.

Abstract: Additive manufacturing apparatus, along with methods of forming an object therewith, are provided. The additive manufacturing apparatus may include at least one build unit; a build platform (such as a rotating build platform); and a pair of collectors positioned on the apparatus such that a first collector contacts an outer surface of an object as it is formed on the build platform and a second collector contacts an inner surface of the object as it is formed on the build platform.

Abstract: At least some aspects of this disclosure include one or more auxinic herbicides with relatively low volatility. Some of these compounds may be especially useful when used in the process of growing commercially important plants. Methods for using these actives to control the growth and spread of unwanted plants and/or to hasten the growth of desirable plants are also disclosed herein.

Abstract: The present disclosure provides methods of treating B-cell malignancy in a subject with a Bcl-2 inhibitor, in particularly 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-((4-((((1r,4r)-4-hydroxy-4-methylcyclohexyl)methyl)amino)-3-nitrophenyl)sulfonyl)-4-(2-((S)-2-(2-isopropylphenyl)pyrrolidin-1-yl)-7-azaspiro[3.5]nonan-7-yl)benzamide or a pharmaceutically acceptable salt thereof, or its combination with a Bruton's tyrosine kinase (BTK) inhibitor, particularly (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof.

Abstract: An anode apparatus for mounting on an external surface of a concrete structure to provide cathodic protection of metal members in the concrete uses a pre-assembled body which is typically elongate carrying a longitudinal anode, which can be sacrificial or impressed current, together with a supporting material having a front face for attachment to the surface and an impermeable plastic covering material at the rear face covering the anode and the supporting material when the front face is attached to the surface of the concrete. A channel defined on the front face is arranged to receive a layer of a conformable ionically conductive adhesive material for attachment to the external surface. A distance of the edge of the covering material is arranged to be similar to a distance of the metal from the external surface such that wetting and drying effects of environmental moisture are the same for the anode as for the metal components.

Abstract: A liquid chromatography sample manager includes a thermal chamber, a sample platter mounted in the thermal chamber, and a needle drive including a base having a shaft configured to rotate about a vertical axis, the base attachable to an interior of a sample manager of a liquid chromatography system. The needle drive further includes a needle assembly attached to the base, the needle assembly including a sample needle, and a drive system attached to the base, the drive system including a sample needle motor configured to impart vertical movement of the sample needle. The liquid chromatography sample manager further includes a sample delivery system configured to transfer a first sample from a first sample vial carrier located in the sample platter into a chromatographic flow stream.

Abstract: A method and a fluidic network for acquiring and injecting a chromatographic sample into a chromatography system flow include a metering pump module, a sample needle, a needle seal and an injection valve. The metering pump module includes a metering pump and a pressure transducer in serial fluidic communication. When the injection valve is in a first valve state, the injection valve is configured to fluidically terminate ports of the metering pump module. When the injection valve is in a second valve state, the injection valve is configured to fluidically couple a fluidic path that includes the metering pump module and sample needle into the system flow of a chromatography system without resulting in a substantial change in the pressure of the system flow.

Abstract: A device having a Graphics Processing Unit (GPU) may be configured to selectively run in a normal mode or a timing testing mode. In the timing testing mode the device is configured to disrupt timing of processing that takes place on the GPU while running an application with the GPU and test the application for errors in device hardware component and/or software component synchronization while the device is running in the timing testing mode.

Abstract: The present invention relates to a group of novel compounds, methods for their manufacture and the use of these compounds as research tools and as pharmaceuticals. The novel compounds are analogues of cannabidiol (CBD). CBD is a non-psychoactive cannabinoid which has been used to treat various diseases and disorders. While such treatments hold promise, there remains a need in the art for more effective treatments and this has been brought about by way of novel cannabidiol compounds.

Abstract: A liquid chromatography sample manager includes a sampling mechanism; a sample platter mounted in the sampling mechanism, the sample platter configured to rotate about a first vertical axis; a needle arm mounted within the sampling mechanism, the needle arm configured to rotate about a second vertical axis; and a sample delivery system in fluidic communication with solvent delivery system, the sample delivery system including a sample needle attached to the needle arm, the sample delivery system configured to transfer a first sample from a first sample vial carrier located in the sample platter into a chromatographic flow stream.

Abstract: A new device executing an application on a new central processing unit (CPU), determines whether the application is for a legacy device having a legacy CPU. When the new device determines that the application is for the legacy device, it executes the application on the new CPU with selected available resources of the new device restricted to approximate or match a processing behavior of the legacy CPU, e.g., by reducing a usable portion of a return address stack of the new CPU and thereby reducing a number of calls and associated returns that can be tracked.

Abstract: A method and a fluidic network for acquiring and injecting a chromatographic sample into a chromatography system flow include a metering pump module, a sample needle, a needle seal and an injection valve. The metering pump module includes a metering pump and a pressure transducer in serial fluidic communication. When the injection valve is in a first valve state, the injection valve is configured to fluidically terminate ports of the metering pump module. When the injection valve is in a second valve state, the injection valve is configured to fluidically couple a fluidic path that includes the metering pump module and sample needle into the system flow of a chromatography system without resulting in a substantial change in the pressure of the system flow.

Abstract: An application designed for the current version of a system runs at a standard clock frequency of a current version of the system. Running the application at the standard clock frequency includes synchronizing operation of a processor of the current version of the system with the standard clock frequency. An application designed for a different version of the system characterized by a different standard clock frequency runs at a second clock frequency that is different than the standard clock frequency. Running the application at the second clock frequency includes synchronizing operation of the processor of the current version of the system with the second clock frequency.

Abstract: One or more aspects of the present disclosure are directed to techniques for interference cancellation in the present of Multi-User Interference (MUI). In one aspect, a method includes receiving a mixture signal at a receiver, the mixture signal including a first intended signal and at least one interfering signal overlappingly transmitted with the first intended signal; processing the mixture signal to identify the at least one interfering signal, the processing including at least applying an adaptive filtering to a re-modulated version of each of the at least one interfering signal to yield at least one reconstructed interfering signal; and determining the first intended signal using the mixture signal and the at least one reconstructed interfering signal.

Abstract: One or more aspects of the present disclosure are directed to network optimization solutions provided as software agents (applications) executed on network nodes in a heterogenous multi-vendor environment to provide cross-layer network optimization and ensure availability of network resources to meet associated Quality of Experience (QoE) and Quality of Service (QoS). In one aspect, a network slicing engine is configured to receive at least one request from at least one network endpoint for access to the heterogeneous multi-vendor network for data transmission; receive information on state of operation of a plurality of communication links between the plurality of nodes; determine a set of data transmission routes for the request; assign a network slice for serving the request; determine, from the set of data transmission routes, an end-to-end route for the network slice; and send network traffic associated with the request using the network slice and over the end-to-end route.

Abstract: Described is a metering pump that may be used to meter volumes of sample in a chromatography system. The metering pump has a modular configuration that allows for separation of a head pod from a drive assembly for easy serviceability. The head pod includes a pump head, cartridge housing, seal wash housing and plunger. The drive assembly can be implemented in an inline drive configuration. Alternatively, the drive assembly can be implemented in an offset drive configuration in which a stepper motor is displaced laterally from other drive assembly components but is coupled through a belt and pulley system.

Abstract: The present disclosure relates, in general, to: (a) solid pharmaceutical dosage forms comprising acalabrutinib maleate; (b) methods of using such pharmaceutical dosage forms to treat B-cell malignancies and/or other conditions; (c) kits comprising such pharmaceutical dosage forms and, optionally, a second pharmaceutical dosage form comprising another therapeutic agent; (d) methods for the preparation of such pharmaceutical dosage forms; and (e) pharmaceutical dosage forms prepared by such methods.