Abstract: Anti-PVRIG and anti-TIGIT antibodies are provided.

Abstract: Methods for treating eye diseases associated with inflammation and/or vascular proliferation in subjects are disclosed. The methods include administering therapeutically effective amounts of a tranilast compound, in particular (E)-2-[[3-(3-Methoxy-4-propargyloxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or (E)-2-[[3,4-Bis(difluoromethoxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or pharmaceutically acceptable salts or solvates thereof.

Abstract: An identification assembly is provided having a tag assembly and a bracket assembly, the tag assembly comprising a front plate rotatably fixed to a tag body. In accordance with embodiments, the front plate has two identification surfaces and the tag body has one identification surface, and the tag assembly is configured to removably receive the bracket assembly.

Abstract: An identification assembly is provided having a tag assembly and a bracket assembly, the tag assembly comprising a front plate rotatably fixed to a tag body. In accordance with embodiments, the front plate has two identification surfaces and the tag body has one identification surface, and the tag assembly is configured to removably receive the bracket assembly.

Abstract: Methods for treating eye diseases associated with inflammation and/or vascular proliferation in subjects are disclosed. The methods include administering therapeutically effective amounts of a tranilast compound, in particular (E)-2-[[3-(3-Methoxy-4-propargyloxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or (E)-2-[[3,4-Bis(difluoromethoxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or pharmaceutically acceptable salts or solvates thereof.

Abstract: Methods for treating eye diseases associated with inflammation and/or vascular proliferation in subjects are disclosed. The methods include administering therapeutically effective amounts of a tranilast compound, in particular (E)-2-[[3-(3-Methoxy-4-propargyloxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or (E)-2-[[3,4-Bis(difluoromethoxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or pharmaceutically acceptable salts or solvates thereof.

Abstract: A cutter assembly includes a rotatable cutting head carrying outwardly extending cutter blades, as well as a rotatable drive hub and interconnected spring housing. The drive hub has a bearing housing, whereas spring housing includes coil spring. The spring housing is operably coupled with the cutting head, in a manner such that the spring exerts an unrestrained force against the cutting head and blades so that there is unrestrained movement of these components toward the outlet face of an extruder die plate. Consequently, there is a substantially constant self-adjusting force exerted on the cutter and blades against the plate, which promotes cleaner cutting of extrudate, even in the event that there is a degree of misalignment between the cutting edges and the outer surface of die plate. This arrangement lengthens the service life of the blades and the die plate.

Abstract: Methods for treating eye diseases associated with inflammation and/or vascular proliferation in subjects are disclosed. The methods include administering therapeutically effective amounts of a tranilast compound, in particular (E)-2-[[3-(3-Methoxy-4-propargyloxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or (E)-2-[[3,4-Bis(difluoromethoxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or pharmaceutically acceptable salts or solvates thereof.

Abstract: Disclosed is a semiconductor device 2 comprising a radio transmitter hardware section 10 and a processor 4, the device 2 being arranged to transmit information via said transmitter hardware section 10 from a first application running on the processor 4 in accordance with a first communication protocol or from a second application running on the processor 4 or a further processor using a second communication protocol, wherein the first application is configured to generate a first transmit request 24 when it requires to send a data packet and wherein the second application is configured to generate a second transmit request 34 when the second application requires to send a data packet, the device further comprising control logic 22 for allocating a transmission timeslot for said transmitter section 10 to said first or second application upon receipt of said first 24 or second 34 transmit requests respectively.

Abstract: An example system may include a computing device and an additive manufacturing tool. The computing device may define a digital representation of an inclined channel at least partially within a component, including an angle ? based on a formula ?=2 tan?1 [tan(?/2)/sin(?)]. The inclined channel may define a longitudinal axis inclined at the angle ? relative to a build direction, and may include a gabled roof configured to collapse into an arched roof. The angle ? is a predetermined interior angle of the gabled roof measured in a plane substantially parallel to the build direction. The angle ? is an interior angle of the gabled roof in a plane substantially normal to the inclined longitudinal axis. The computing device may control, based on the digital representation, the additive manufacturing tool to deposit a material along the build direction to fabricate the component including the inclined channel.

Abstract: The present disclosure relates to techniques for stress relief in additive layer manufacturing (ALM). Example embodiments include a method for additive layer manufacturing of a metallic component, comprising the steps of: providing a substrate (20); depositing a first layer (22) of material on the substrate (20); depositing a plurality of second layers of material on the first layer (22) to form the metallic component (21), wherein the first layer (22) forms a stress relieving layer between the plurality of second layers and the substrate (20), the stress relieving layer having a lower shear stiffness compared to the metallic component (21).

Abstract: An identification assembly is provided having a tag assembly and a bracket assembly, the tag assembly comprising a front plate rotatably fixed to a tag body. In accordance with embodiments, the front plate has two identification surfaces and the tag body has one identification surface, and the tag assembly is configured to removably receive the bracket assembly.

Abstract: A cutter assembly includes a rotatable cutting head carrying outwardly extending cutter blades, as well as a rotatable drive hub and interconnected spring housing. The drive hub has a bearing housing, whereas spring housing includes coil spring. The spring housing is operably coupled with the cutting head, in a manner such that the spring exerts an unrestrained force against the cutting head and blades so that there is unrestrained movement of these components toward the outlet face of an extruder die plate. Consequently, there is a substantially constant self-adjusting force exerted on the cutter and blades against the plate, which promotes cleaner cutting of extrudate, even in the event that there is a degree of misalignment between the cutting edges and the outer surface of die plate. This arrangement lengthens the service life of the blades and the die plate.

Abstract: Method of processing a layer of material in layer-by-layer additive manufacturing process is provided, wherein successive layers of flowable material are formed and a laser beam is scanned across a selected area of each layer to consolidate the material in said selected area. The method comprises providing a first raster path for a laser beam, the first raster path having a defined spacing between successive passes, and providing at least one further raster path for a laser beam, wherein the or each further raster path has the same defined spacing between successive passes as the first raster path and is offset from the first raster path in the direction of said defined spacing by a distance that is less than said defined spacing, such that the laser beam irradiates the entire selected area in a single pass over the first path and the or each further path.

Abstract: A radio communication system comprises a radio transmitter (2), and a radio receiver (12) configured to receive radio transmissions from the transmitter. The transmitter (2) uses a transmitter clock signal to transmit a succession of connection-event data packets (22a?, 22b?, 22c?) according to a predetermined schedule. The receiver (12) enters a sleep state between receiving successive connection-event data packets from the transmitter (2), in which it does not receive and process radio transmissions from the transmitter. It uses a receiver clock signal to determine when a predetermined number of receiver clock cycles has elapsed after receiving one of the connection-event data packets (22b?), and then enters a ready state. The predetermined number of receiver clock cycles is the number of receiver clock cycles (34a) that elapsed between the respective receipts of two of the connection-event data packets (22a?, 22b?) received by the receiver (12) minus a correction factor (38).

Abstract: Disclosed is a semiconductor device 2 comprising a radio transmitter hardware section 10 and a processor 4, the device 2 being arranged to transmit information via said transmitter hardware section 10 from a first application running on the processor 4 in accordance with a first communication protocol or from a second application running on the processor 4 or a further processor using a second communication protocol, wherein the first application is configured to generate a first transmit request 24 when it requires to send a data packet and wherein the second application is configured to generate a second transmit request 34 when the second application requires to send a data packet, the device further comprising control logic 22 for allocating a transmission timeslot for said transmitter section 10 to said first or second application upon receipt of said first 24 or second 34 transmit requests respectively.

Abstract: Disclosed is a semiconductor device 2 comprising a radio transmitter hardware section 10 and a processor 4, the device 2 being arranged to transmit information via said transmitter hardware section 10 from a first application running on the processor 4 in accordance with a first communication protocol or from a second application running on the processor 4 or a further processor using a second communication protocol, wherein the first application is configured to generate a first transmit request 24 when it requires to send a data packet and wherein the second application is configured to generate a second transmit request 34 when the second application requires to send a data packet, the device further comprising control logic 22 for allocating a transmission timeslot for said transmitter section 10 to said first or second application upon receipt of said first 24 or second 34 transmit requests respectively.

Abstract: Methods for treating eye diseases associated with inflammation and/or vascular proliferation in subjects are disclosed. The methods include administering therapeutically effective amounts of a tranilast compound, in particular (E)-2-[[3-(3-Methoxy-4-propargyloxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or (E)-2-[[3,4-Bis(difluoromethoxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or pharmaceutically acceptable salts or solvates thereof.

Abstract: Methods for treating eye diseases associated with inflammation and/or vascular proliferation in subjects are disclosed. The methods include administering therapeutically effective amounts of a tranilast compound, in particular (E)-2-[[3-(3-Methoxy-4-propargyloxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or (E)-2-[[3,4-Bis(difluoromethoxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or pharmaceutically acceptable salts or solvates thereof.