Patents by Inventor David Stern

David Stern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200188020
    Abstract: Systems, devices, and methods to treat a urinary bladder are disclosed. An expandable member is introduced and expanded in the urinary bladder to appose one or more elongate conductors on the outer surface of the expandable member against the inner wall of the urinary bladder. The one or more elongate conductors are used to create a predetermined pattern of electrically isolated tissue regions having reduced electrical propagation such that electrical propagation through the urinary bladder as a whole is reduced. A mucus layer may be removed from the inner bladder wall prior to the ablation. Ablation may be regulated by impedance measurement with the one or more elongate conductors. The urinary bladder may be filled with a fluid to facilitate the impedance measurement.
    Type: Application
    Filed: February 25, 2020
    Publication date: June 18, 2020
    Inventors: Omry BEN-EZRA, Itzhak AVNERI, David STASKIN, Roger A. STERN, Jerome JACKSON, Benjamin WANG
  • Patent number: 10610294
    Abstract: Systems, devices, and methods to treat a urinary bladder are disclosed. An expandable member is introduced and expanded in the urinary bladder to appose one or more elongate conductors on the outer surface of the expandable member against the inner wall of the urinary bladder. The one or more elongate conductors are used to create a predetermined pattern of electrically isolated tissue regions having reduced electrical propagation such that electrical propagation through the urinary bladder as a whole is reduced. A mucus layer may be removed from the inner bladder wall prior to the ablation. Ablation may be regulated by impedance measurement with the one or more elongate conductors. The urinary bladder may be filled with a fluid to facilitate the impedance measurement.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: April 7, 2020
    Assignee: NewUro, B.V.
    Inventors: Omry Ben-Ezra, Itzhak Avneri, David Staskin, Roger A. Stern, Jerome Jackson, Benjamin Wang
  • Patent number: 10607498
    Abstract: A computer implemented method for distributing, collecting, monitoring and releasing assignments by a content management system. The method includes distributing file requests for assignments to students. Each file request includes one or more metadata tags. Students submit assignments in response to the file requests with the assignments being stored and associated with the file requests using the one or more metadata tags. In response to a release command, the assignments are searched based on one or more metadata tags and assignments associated with a student can be released to the student.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: March 31, 2020
    Assignee: Dropbox, Inc.
    Inventors: Kelly Bonney-Ache, Ritu Moondra, Calvin Low, Kristen Witte, David Fish, Ian Macartney, Ben Stern
  • Patent number: 10586326
    Abstract: Systems and methods for generating biomarkers associated with neuropsychiatric disorders, neurodevelopmental disorders, neurobehavioral disorders, or other neurological disorders are described. In general, the biomarkers are generated based on correlations between functional imaging data and clinical acquired from a subject, as computed using a multivariate classifier. Functional imaging data may include functional magnetic resonance images, or activation maps generated from such images. Clinical data generally includes data associated with a clinical or behavioral characterization of the subject. The biomarkers can be used to monitor or otherwise assess a treatment response; to provide diagnostic information, such as subtyping or classifying a disorder; to provide prognostic information, such as a prediction of treatment response or outcome; or to indicate functional or anatomical targets for treatments.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: March 10, 2020
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: David Silbersweig, Emily Stern, Hong Pan
  • Patent number: 10586095
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: March 10, 2020
    Assignee: Affymetrix, Inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • Patent number: 10585296
    Abstract: Disclosed herein is a high throughput optical scanning device and methods of use. The optical scanning device and methods of use provided herein can allow high throughput scanning of a continuously moving object with a high resolution despite fluctuations in stage velocity. This can aid in high throughput scanning of a substrate, such as a biological chip comprising fluorophores. Also provided herein are improved optical relay systems and scanning optics.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: March 10, 2020
    Assignee: APTON BIOSYSTEMS, INC.
    Inventors: Windsor Owens, Bryan Staker, Rob Hartlage, Edvinas Zizminskas, David Stern, Paul Heilman
  • Publication number: 20200033434
    Abstract: A system and method for imaging a subject includes a first imaging pulse sequence having gradient blips along an x-direction and a y-direction to acquire calibration image data from multiple slices. The imaging pulse sequence also includes a plurality of Z-shimming gradient blips coincident in time with the gradient blips along the x- and y-directions and varied within each slice. A plurality of calibration images are reconstructed from the calibration image data and a comparison image is formed by selecting an image from the calibration images corresponding to at least one of the varied Z-shimming gradient blips for each slice to determine a desired value of the Z-shimming gradient blips. The desired values are used to perform a second pulse sequence to acquire clinical image data from the subject. The second pulse sequence is used to acquire clinical images having been compensated for magnetic susceptibility variations within the subject.
    Type: Application
    Filed: April 8, 2019
    Publication date: January 30, 2020
    Inventors: Emily Stern, David Silbersweig, Hong Pan, Yihong Yang, Hong Gu
  • Patent number: 10540739
    Abstract: A predictive application cache is described. The predictive application cache intelligently selects which applications to cache to maximize caching effectiveness. In an embodiment, the selecting is based on user input and a graphical user interface. The predictive application cache then determines, based on the user input and the graphical user interface, which applications are likely to be selected by user input next. In an embodiment, the selecting is also based on historical usage information. In an embodiment, the selecting is based on crowd sourced information.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: January 21, 2020
    Assignee: Roku, Inc.
    Inventors: David Stern, Anthony Wood
  • Publication number: 20190311178
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Application
    Filed: April 3, 2019
    Publication date: October 10, 2019
    Applicant: Affymetrix, Inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • Patent number: 10437304
    Abstract: Streaming content using a data streaming device having limited power is described. A data streaming device receives streaming content from a network and provides the streaming content for display on a content display device. Data streaming device includes power supplies that receive power from the content display device. The power supplies use the power to operate components of data streaming device that process the streaming content. A measuring module measures the power provided to the data streaming device. When the power is insufficient, a controller generates an indication that there is insufficient power to operate the components of the data streaming device. The controller may also modify functionality of the components to operate using available power or disable a component of the data streaming device.
    Type: Grant
    Filed: March 15, 2016
    Date of Patent: October 8, 2019
    Assignee: Roku, Inc.
    Inventors: Gregory Garner, Anthony Wood, Simon Martin, David Stern
  • Publication number: 20190302864
    Abstract: Streaming content using a data streaming device having limited power is described. A data streaming device receives streaming content from a network and provides the streaming content for display on a content display device. Data streaming device includes power supplies that receive power from the content display device. The power supplies use the power to operate components of data streaming device that process the streaming content. A measuring module measures the power provided to the data streaming device. When the power is insufficient, a controller generates an indication that there is insufficient power to operate the components of the data streaming device. The controller may also modify functionality of the components to operate using available power or disable a component of the data streaming device.
    Type: Application
    Filed: June 21, 2019
    Publication date: October 3, 2019
    Inventors: Gregory GARNER, Anthony Wood, Simon Martin, David Stern
  • Patent number: 10413900
    Abstract: The present disclosure provides microfluidic devices, systems and methods for sample preparation and/or analysis. A microfluidic device can include a first channel having a sequence of (n) chambers each having a first volume (v). The first channel can include one or more valves at opposing ends of the first channel that fluidically isolate the first channel. The microfluidic device can further include a second channel in fluid communication with the first channel. The second channel can include at least one second chamber having a total second volume that is at least equal to the total volume of the first channel (n*v). The second channel can include one or more valves at opposing ends of the second channel that fluidically isolate the second channel from the first channel.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: September 17, 2019
    Assignee: GENAPSYS, INC.
    Inventors: Seth Stern, Hesaam Esfandyarpour, David Eberhart
  • Patent number: 10384189
    Abstract: Compositions, devices, methods and systems are provided for differential functionalization of a surface of a structure to support biopolymer synthesis. Provided herein are processes which include use of lamps, lasers, and/or microcontact printing to add functional groups to surfaces for the efficient and uniform synthesis of oligonucleic acids.
    Type: Grant
    Filed: January 2, 2018
    Date of Patent: August 20, 2019
    Assignee: Twist Bioscience Corporation
    Inventors: Bill James Peck, Pierre Indermuhle, Eugene P. Marsh, Andres Fernandez, David Stern
  • Publication number: 20190240636
    Abstract: Compositions, devices, methods and systems are provided for differential functionalization of a surface of a structure to support biopolymer synthesis. Provided herein are processes which include use of lamps, lasers, and/or microcontact printing to add functional groups to surfaces for the efficient and uniform synthesis of oligonucleic acids.
    Type: Application
    Filed: April 15, 2019
    Publication date: August 8, 2019
    Inventors: Bill James PECK, Pierre INDERMUHLE, Eugene P. MARSH, Andres FERNANDEZ, David STERN
  • Patent number: 10303922
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: May 28, 2019
    Assignee: Affymetrix, Inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • Publication number: 20190066673
    Abstract: Disclosed herein are embodiments for an audio responsive electronic device. The audio responsive electronic device includes a data storage having stored therein an intent queue. Intents are stored in the intent queue. The audio responsive electronic device operates by receiving an indication that a user pressed the play/stop button. The audio responsive electronic device retrieves from the intent queue an intent last stored in the queue, wherein the retrieved intent is associated with content previously paused. The audio responsive electronic device also retrieves from the intent queue state information associated with the paused content, and then causes content to be played based on at least the paused content and the state information. In some embodiments, the audio responsive electronic device receives an indication that a user selected tell me something functionality.
    Type: Application
    Filed: July 11, 2018
    Publication date: February 28, 2019
    Applicant: Roku, Inc.
    Inventors: Anthony John WOOD, David STERN, Gregory Mack GARNER
  • Publication number: 20190066687
    Abstract: Disclosed herein are system, apparatus, article of manufacture, method and/or computer program product embodiments, and/or combinations and sub-combinations thereof, for distributing the performance of speech recognition among a remote control device and a voice platform in the cloud. In some embodiments, the remote control device operates to receive a voice input from a user. The remote control device detects a trigger word in the voice input. The remote control device then processes the voice input. The remote control device then transmits the voice input to a voice platform based on the detecting in order to determine an intent associated with the voice input.
    Type: Application
    Filed: July 11, 2018
    Publication date: February 28, 2019
    Applicant: Roku, Inc.
    Inventors: Anthony John WOOD, David Stern, Gregory Mack Garner
  • Publication number: 20190066672
    Abstract: Disclosed herein are system, apparatus, article of manufacture, method and/or computer program product embodiments, and/or combinations and sub-combinations thereof, for providing voice control using multiple digital assistants. In some embodiments, a voice platform operates to receive a voice input from a user. The voice platform selects a digital assistant from a plurality of digital assistants based on a trigger word. The voice platform then generates an intent from the voice input using the selected digital assistant. The voice platform then transmits the intent to a media device for processing.
    Type: Application
    Filed: July 11, 2018
    Publication date: February 28, 2019
    Applicant: Roku, Inc.
    Inventors: Anthony John WOOD, David Stern, Gregory Mack Garner
  • Publication number: 20180341802
    Abstract: In one embodiment of the invention, a method to image a probe array is described that includes focusing on a plurality of fiducials on a surface of an array. The method utilizes obtaining the best z position of the fiducials and using a surface fitting algorithm to produce a surface fit profile. One or more surface non-flatness parameters can be adjusted to improve the flatness image of the array surface to be imaged.
    Type: Application
    Filed: May 30, 2018
    Publication date: November 29, 2018
    Applicant: Affymetrix, Inc.
    Inventors: David Stern, Chuan Gao, Melvin Yamamoto, Devin Nguyen
  • Publication number: 20180252936
    Abstract: Disclosed herein is a high throughput optical scanning device and methods of use. The optical scanning device and methods of use provided herein can allow high throughput scanning of a continuously moving object with a high resolution despite fluctuations in stage velocity. This can aid in high throughput scanning of a substrate, such as a biological chip comprising fluorophores. Also provided herein are improved optical relay systems and scanning optics.
    Type: Application
    Filed: March 2, 2018
    Publication date: September 6, 2018
    Inventors: Windsor Owens, Bryan Staker, Rob Hartlage, Edvinas Zizminskas, David Stern, Paul Heilman