Abstract: This invention relates to an apparatus, device or method for manufacturing a grip plectrum or pick formed from a first material (such as, for example, plastic or like material), the plectrum having in one embodiment a generally triangular shaped body with a broad top portion, an intermediate portion, and a narrow bottom portion, with the top and intermediate portion being substantially covered with a second material that has a greater degree of grip than the first material. The plectrum has a generally triangular (and preferably tear-drop) shaped body being made from a first material. A top and intermediate portion of the plectrum are substantially or completely covered by a second material on all four sides (front surface, back surface and both side surfaces) and is adapted to be gripped by the user between the thumb and index finger, with a bottom portion being used to pluck the instrument strings. In one embodiment, the second material is preferably a non-slip material such as rubber or the like.

Abstract: The present invention relates to a pharmaceutical composition and a process for the preparation of a tablet containing a growth hormone secretagogue as the active ingredient. The tablet is prepared by forming a powder blend of the active ingredient N-[1(R)-[(1,2-dihydro-1-methanesulfonyl-spiro[3H-indole-3,4'-piperdin]-1'- yl)carbonyl]-2-(phenylmethyl-oxy)ethyl]-2-amino-2-methyl-propanamide, or a pharmaceutically acceptable salt thereof, in particular the methanesulfonate salt, with a binder/diluent, a first diluent, a second diluent, a first portion of a disintegrant, and a lubricant; wet granulating the powder blend with a solution of ethanol/water to form granules; drying the granules to remove the ethanol/water; adding a second portion of a disintegrant; lubricating the granules; and compressing the dried granules into the desired tablet form.