Patents by Inventor David T. Breslin

David T. Breslin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180155329
    Abstract: The present invention is directed to an anhydrous crystalline for of (1S)-1,5-anhydro-1-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol, pharmaceutical compositions containing said anhydrous crystalline form and its use in the treatment glucose-related disorders such as Type 2 diabetes mellitus and Syndrome X.
    Type: Application
    Filed: May 18, 2016
    Publication date: June 7, 2018
    Applicant: Janssen Pharmaceutica NV
    Inventors: David T. Breslin, Nagy E. Fawzy, John Schaefer
  • Patent number: 6979676
    Abstract: The present invention is directed to a pharmaceutical composition comprising a compound of Formula I dissolved in propylene glycol and water. The present invention also relates to a pharmaceutical composition containing a compound of Formula I dissolved in propylene glycol and a buffer that has a pH between about 3 and about 5.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: December 27, 2005
    Assignees: Merck & Co., Inc., Banyu Pharmaceutical Co., Ltd.
    Inventors: Yuichi Sato, David T. Breslin, Shyam B. Karki
  • Publication number: 20040029821
    Abstract: The present invention is directed to a pharmaceutical composition comprising a compound of Formula I dissolved in propylene glycol and water. The present invention also relates to a pharmaceutical composition containing a compound of Formula I dissolved in propylene glycol and a buffer that has a pH between about 3 and about 5.
    Type: Application
    Filed: September 26, 2002
    Publication date: February 12, 2004
    Inventors: Yuichi Sato, David T. Breslin, Shyam B. Karki
  • Patent number: 5470994
    Abstract: Sulfonium and oxysulfonium salts, useful as photoinitiators, have directly attached to the sulfur atom thereof:at least one aromatic or heterocyclic aromatic substituent containing at least 14 aromatic atoms and having a removable positive hydrogen ion, said substituent exhibiting a higher energy occupied molecular orbital than at least one other substituent directly attached to said sulfur atom;and at least one substituent comprising an electron withdrawing group and exhibiting a lower energy unoccupied molecular orbital than at least one other substituent directly attached to said sulfur atom;said salt being capable, upon exposure to visible radiation, of undergoing irreversible intramolecular rearrangement to form a Bronsted acid comprising the anion of said salt and said removable positive hydrogen ion.
    Type: Grant
    Filed: April 5, 1990
    Date of Patent: November 28, 1995
    Assignee: Eastman Kodak Company
    Inventors: Franklin D. Saeva, David T. Breslin
  • Patent number: 5141969
    Abstract: Sulfonium, selenonium, arsonium, ammonium and phosphonium salts, useful as photoinitiators, comprise:a chromophore which absorbs visible radiation, the chromophore (1) having a removable positive hydrogen ion and (2) exhibiting a higher energy occupied molecular orbital than at least one other substituent attached to the S, Se, As, N or P atom of the salt;an insulating group which links the chromophore to the S, Se, As, N or P atom of the salt, the insulating group essentially preventing .pi. resonance between the chromophore and the other substituents in the salt;at least one substituent comprising an electron withdrawing group and exhibiting a lower unoccupied molecular orbital than the chromophore; and,an anion;the salts being capable, upon exposure to visible radiation, of forming a Bronsted acid.
    Type: Grant
    Filed: October 10, 1989
    Date of Patent: August 25, 1992
    Assignee: Eastman Kodak Company
    Inventors: Franklin D. Saeva, David T. Breslin
  • Patent number: 4933377
    Abstract: Sulfonium and oxysulfonium salts, useful as photoinitiators, have directly attached to the sulfur atom thereof:at least one aromatic or heterocyclic aromatic substituent containing at least 14 aromatic atoms and having a removable positive hydrogen ion, said substituent exhibiting a higher energy occupied molecular orbital than at least one other substituent directly attached to said sulfur atom;and at least one substituent comprising an electron withdrawing group and exhibiting a lower energy unoccupied molecular orbital than at least one other substituent directly attached to said sulfur atom;said salt being capable, upon exposure to visible radiation, of undergoing irreversible intramolecular rearrangement to form a Bronsted acid comprising the anion of said salt and said removable positive hydrogen ion.
    Type: Grant
    Filed: February 29, 1988
    Date of Patent: June 12, 1990
    Inventors: Franklin D. Saeva, David T. Breslin