Patents by Inventor David T. MacPherson

David T. MacPherson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARING SPIRO DERIVATIVES
    Publication number: 20220033408
    Abstract: The invention relates to a novel process for preparing spiro derivatives, in particular 7-methyl-2-[4-methyl-6-[4-(trifluoromethyl)-phenyl]pyrimidin-2-yl]-1,7-diazaspiro[4.4]nonan-6-one, and to novel intermediates for use in said process along with processes for preparing said intermediates.
    Type: Application
    Filed: October 15, 2021
    Publication date: February 3, 2022
    Inventors: Gerard M. Giblin, David T. MacPherson, Osama Suleiman, Michael Williams, David R. Witty, Thierry Bonnaud, Richard Edwards
  • Process for preparing spiro derivatives
    Patent number: 11149039
    Abstract: The invention relates to a novel process for preparing Spiro derivatives, in particular 7-methyl-2-[4-methyl-6-[4-(trifluoromethyl)-phenyl]pyrimidin-2-yl]-1,7-diazaspiro[4.4]nonan-6-one, and to novel intermediates for use in said process along with processes for preparing said intermediates.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: October 19, 2021
    Assignee: Biogen Inc.
    Inventors: Gerard M. Giblin, David T. MacPherson, Osama Suleiman, Michael Williams, David R. Witty, Thierry Bonnaud, Richard Edwards
  • PROCESS FOR PREPARING SPIRO DERIVATIVES
    Publication number: 20200325144
    Abstract: The invention relates to a novel process for preparing Spiro derivatives, in particular 7-methyl-2-[4-methyl-6-[4-(trifluoromethyl)-phenyl]pyrimidin-2-yl]-1,7-diazaspiro[4.4]nonan-6-one, and to novel intermediates for use in said process along with processes for preparing said intermediates.
    Type: Application
    Filed: October 10, 2018
    Publication date: October 15, 2020
    Inventors: Gerard M. Giblin, David T. MacPherson, Osama Suleiman, Michael Williams, David R. Witty, Thierry Bonnaud, Richard Edwards
  • NOVEL PYRIMIDINYL-DIAZOSPIRO COMPOUNDS
    Publication number: 20200289508
    Abstract: The invention relates to Spiro derivatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Application
    Filed: October 17, 2019
    Publication date: September 17, 2020
    Inventors: Gerard M.P. Giblin, David T. MacPherson, David R. Witty, Steven J. Stanway
  • NOVEL SALTS
    Publication number: 20200255438
    Abstract: The invention relates to novel salts of 7-methyl-2-[4-methyl-6-[4-(trifluoromethyl)-phenyl]pyrimidin-2-yl]-1,7-diazaspiro[4.4]nonan-6-one, to compositions containing said salts and to the use of said salts in treating diseases and conditions mediated by modulation of voltage-gated sodium channels.
    Type: Application
    Filed: September 28, 2018
    Publication date: August 13, 2020
    Inventors: Gerard M. Giblin, David T. MacPherson, Michael Williams, David R. Witty, Julian Northen, Kalyan Vasudevan
  • Pyrimidinyl-diazospiro compounds
    Patent number: 10485801
    Abstract: The invention relates to spiro derivatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: November 26, 2019
    Assignee: Convergence Pharmaceuticals Limited
    Inventors: Gerard M. P. Giblin, David T. MacPherson, David R. Witty, Steven J. Stanway
  • NOVEL PYRIMIDINYL-DIAZOSPIRO COMPOUNDS
    Publication number: 20180360833
    Abstract: The invention relates to spiro derivatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Application
    Filed: June 27, 2018
    Publication date: December 20, 2018
    Inventors: Gerard M.P. Giblin, David T. MacPherson, David R. Witty, Steven J. Stanway
  • Pyrimidinyl-diazospiro compounds
    Patent number: 10010551
    Abstract: The invention relates to spiro deriviatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: July 3, 2018
    Assignee: Convergence Pharmaceuticals Limited
    Inventors: Gerard M. P. Giblin, David T. MacPherson, David R. Witty, Steven J. Stanway
  • Novel Pyrimidinyl-DiazoSpiro Compounds
    Publication number: 20170304303
    Abstract: The invention relates to spiro deriviatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Application
    Filed: July 11, 2017
    Publication date: October 26, 2017
    Inventors: Gerard M.P. Giblin, David T. MacPherson, David R. Witty, Steven J. Stanway
  • Pyrimidinyl-diazospiro compounds
    Patent number: 9737536
    Abstract: The invention relates to spiro derivatives, to the use of said derivatives intreating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: August 22, 2017
    Assignee: Convergence Pharmaceuticals Limited
    Inventors: Gerard M. P. Giblin, David T. MacPherson, David R. Witty, Steven J. Stanway
  • Novel Pyrimidinyl-DiazoSpiro Compounds
    Publication number: 20160263115
    Abstract: The invention relates to spiro derivatives, to the use of said derivatives intreating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Application
    Filed: May 25, 2016
    Publication date: September 15, 2016
    Inventors: Gerard M. P. Giblin, David T. MacPherson, David R. Witty, Steven J. Stanway
  • Novel Pyrimidinyl-DiazoSpiro Compounds
    Publication number: 20160184306
    Abstract: The invention relates to spiro derivatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Application
    Filed: February 15, 2016
    Publication date: June 30, 2016
    Inventors: Gerard M.P. GIBLIN, David T. MACPHERSON, David R. WITTY, Steven J. STANWAY
  • 2-(Pyridin-2-yl)-1, 7-Diaza-Spiro [4.4] Nonane-6-One Compound as Voltage-Gated Sodium Channel Modulator
    Publication number: 20160185758
    Abstract: The invention relates to spiro derivatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Application
    Filed: February 25, 2016
    Publication date: June 30, 2016
    Inventors: David R. Witty, David T. MacPherson, Gerard M.P. Giblin, Steven J. Stanway
  • Pyrimidinyl-diazospiro compounds
    Patent number: 9376445
    Abstract: The invention relates to spiro derivatives, to the use of said derivatives intreating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: June 28, 2016
    Assignee: Convergence Pharmaceuticals Limited
    Inventors: Gerard M. P. Giblin, David T. MacPherson, David R. Witty, Steven J. Stanway
  • 2-(pyridin-2yl)-1, 7-diaza-spiro [4.4] nonane-6-one compound as voltage-gated sodium channels modulators
    Patent number: 9376436
    Abstract: The invention relates to spiro derivatives of formula (I), to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: June 28, 2016
    Assignee: Convergence Pharmaceuticals Limited
    Inventors: David R. Witty, David T. MacPherson, Gerard M. P. Giblin, Steven J. Stanway, Antonio K. K. Vong
  • Pyrimidinyl-diazospiro compounds
    Patent number: 9309254
    Abstract: The invention relates to spiro derivatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: April 12, 2016
    Assignee: Convergence Pharmaceuticals Limited
    Inventors: Gerard M. P. Giblin, David T. MacPherson, David R. Witty, Steven J. Stanway
  • 2-(pyridin-2YL)-1, 7-diaza-spiro [4.4] nonane-6-one compound as voltage-gated sodium channels modulator
    Patent number: 9303032
    Abstract: The invention relates to spiro derivative of formula (I), to the use of said derivative in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivative and processes for its preparation.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: April 5, 2016
    Assignee: Convergence Pharmaceuticals Limited
    Inventors: David R. Witty, David T. MacPherson, Gerard M. P. Giblin, Steven J. Stanway
  • 2 - (PYRIDIN- 2YL)- 1, 7 -DIAZA-SPIRO [4.4] NONANE- 6 -ONE COMPOUND AS VOLTAGE-GATED SODIUM CHANNELS MODULATORS
    Publication number: 20150225400
    Abstract: The invention relates to spiro derivatives of formula (I), to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Application
    Filed: December 21, 2012
    Publication date: August 13, 2015
    Inventors: David R. Witty, David T. MacPherson, Gerard M.P. Giblin, Steven J. Stanway, Antonio K.K. Vong
  • NOVEL COMPOUNDS
    Publication number: 20150166551
    Abstract: The invention relates to spiro derivatives, to the use of said derivatives intreating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Application
    Filed: May 22, 2013
    Publication date: June 18, 2015
    Inventors: Gerard M.P. Giblin, David T. Macpherson, David R. Witty, Steven J. Stanway
  • NOVEL COMPOUNDS
    Publication number: 20150119404
    Abstract: The invention relates to spiro derivatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation.
    Type: Application
    Filed: May 22, 2013
    Publication date: April 30, 2015
    Applicant: CONVERGANCE PHARMACEUTICALS LIMITED
    Inventors: Gerard M.P. Giblin, David T. Macpherson, David R. Witty, Steven J. Stanway