Patents by Inventor David T. Puerta

David T. Puerta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBACTERIAL COMPOUNDS
    Publication number: 20240150298
    Abstract: Provided herein are heterocyclic compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. The subject compounds and compositions are useful for the treatment of bacterial infections, such as pneumonia.
    Type: Application
    Filed: February 8, 2022
    Publication date: May 9, 2024
    Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Christian PEREZ, David T. PUERTA
  • LPXC INHIBITOR AND METHODS OF MAKING
    Publication number: 20240002373
    Abstract: Provided herein is an LpxC inhibitor compound, as well as methods of making and pharmaceutical compositions comprising said compound, and methods of use thereof in the treatment of disease that would benefit from treatment with an LpxC inhibitor, including gram-negative bacterial infections such as urinary tract infections and the like.
    Type: Application
    Filed: June 27, 2023
    Publication date: January 4, 2024
    Inventors: Min TENG, Baskar NAMMALWAR, David T. PUERTA
  • GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE (QPCTL) PROTEIN INHIBITORS AND USES THEREOF
    Publication number: 20230382891
    Abstract: Described herein are compounds that are glutaminyl-peptide cyclotransferase like (QPCTL) protein modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of QPCTL activity.
    Type: Application
    Filed: October 19, 2021
    Publication date: November 30, 2023
    Inventors: Min TENG, David T. PUERTA, Baskar NAMMALWAR, Christian PEREZ, David LONERGAN, David Pifer MARTIN
  • LpxC inhibitor and methods of making
    Patent number: 11731962
    Abstract: Provided herein is an LpxC inhibitor compound, as well as methods of making and pharmaceutical compositions comprising said compound, and methods of use thereof in the treatment of disease that would benefit from treatment with an LpxC inhibitor, including gram-negative bacterial infections such as urinary tract infections and the like.
    Type: Grant
    Filed: March 24, 2021
    Date of Patent: August 22, 2023
    Assignee: BLACKSMITH MEDICINES, INC.
    Inventors: Min Teng, Baskar Nammalwar, David T. Puerta
  • LPXC INHIBITOR, FORMULATIONS, AND USES THEREOF
    Publication number: 20230201214
    Abstract: Provided herein is an LpxC inhibitor compound, as well as pharmaceutical compositions comprising said compound, and methods of use thereof in the treatment of disease that would benefit from treatment with an LpxC inhibitor, including gram-negative bacterial infections such as urinary tract infections and the like.
    Type: Application
    Filed: February 23, 2023
    Publication date: June 29, 2023
    Inventors: Min TENG, Baskar NAMMALWAR, David T. PUERTA
  • ANTIBACTERIAL COMPOUNDS
    Publication number: 20220324846
    Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Application
    Filed: June 9, 2022
    Publication date: October 13, 2022
    Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Christian PEREZ, Ian YULE, Adele FAULKNER, Holly ATTON, Alastair PARKES, Serge CONVERS-REIGNIER, Michelle SOUTHEY, David T. PUERTA
  • Antibacterial compounds
    Patent number: 11407740
    Abstract: Provided herein are heterocyclic derivative compounds of Formula (II), and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: August 9, 2022
    Assignee: FORGE THERAPEUTICS, INC.
    Inventors: Min Teng, Baskar Nammalwar, Xiaoming Li, Christian Perez, Ian Yule, Adele Faulkner, Holly Atton, Alastair Parkes, Serge Convers-Reignier, Michelle Southey, David T. Puerta
  • ANTIBACTERIAL COMPOUNDS
    Publication number: 20220081421
    Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Application
    Filed: November 14, 2019
    Publication date: March 17, 2022
    Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Ian YULE, Alastair PARKES, Heather TYE, Holly ATTON, Helen WILLIAMS, Adele FAULKNER, Serge CONVERS-REIGNIER, David T. PUERTA
  • LPXC INHIBITOR, FORMULATIONS, AND USES THEREOF
    Publication number: 20210315902
    Abstract: Provided herein is an LpxC inhibitor compound, as well as pharmaceutical compositions comprising said compound, and methods of use thereof in the treatment of disease that would benefit from treatment with an LpxC inhibitor, including gram-negative bacterial infections such as urinary tract infections and the like.
    Type: Application
    Filed: March 24, 2021
    Publication date: October 14, 2021
    Inventors: Min TENG, Baskar NAMMALWAR, David T. PUERTA
  • LPXC INHIBITOR AND METHODS OF MAKING
    Publication number: 20210309651
    Abstract: Provided herein is an LpxC inhibitor compound, as well as methods of making and pharmaceutical compositions comprising said compound, and methods of use thereof in the treatment of disease that would benefit from treatment with an LpxC inhibitor, including gram-negative bacterial infections such as urinary tract infections and the like.
    Type: Application
    Filed: March 24, 2021
    Publication date: October 7, 2021
    Inventors: Min TENG, Baskar NAMMALWAR, David T. PUERTA
  • ANTIBACTERIAL COMPOUNDS
    Publication number: 20210221796
    Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Application
    Filed: March 18, 2021
    Publication date: July 22, 2021
    Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Christian PEREZ, Ian YULE, Adele FAULKNER, Holly ATTON, Alastair PARKES, Serge CONVERS-REIGNIER, Michelle SOUTHEY, David T. PUERTA
  • Antibacterial compounds
    Patent number: 11021471
    Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: June 1, 2021
    Assignee: FORGE THERAPEUTICS, INC.
    Inventors: Min Teng, Baskar Nammalwar, Konstantin Taganov, Xiaoming Li, David T. Puerta
  • SUBSTITUTED PYRIMIDINES FOR TREATING BACTERIAL INFECTIONS
    Publication number: 20210078957
    Abstract: The present teachings relate to hydroxypyridinone and hydroxypyrimidinone derivatives, pharmaceutical compositions thereof, and methods of using such compounds to treat bacterial infections.
    Type: Application
    Filed: November 24, 2020
    Publication date: March 18, 2021
    Inventors: Min TENG, Baskar NAMMALWAR, Konstantin TAGANOV, David T. PUERTA
  • Compositions and methods for inhibiting influenza RNA polymerase PA endonuclease
    Patent number: 10889556
    Abstract: There are provided inter alia metalloenzyme inhibitors, such as inhibitors of influenza A RNA dependent RNA polymerase PA subunit endonuclease, and methods of synthesis and use of the same.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: January 12, 2021
    Assignee: The Regents of the University of California
    Inventors: Seth M. Cohen, Cy V. Credille, David T. Puerta
  • Substituted pyrimidines for treating bacterial infections
    Patent number: 10875832
    Abstract: The present teachings relate to hydroxypyrimidinone derivatives of Formula II, pharmaceutical compositions thereof, and methods of using such compounds to treat bacterial infections.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: December 29, 2020
    Assignee: FORGE THERAPEUTICS, INC.
    Inventors: Min Teng, Baskar Nammalwar, Konstantin Taganov, David T. Puerta
  • ANTIBACTERIAL COMPOUNDS
    Publication number: 20200255413
    Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Application
    Filed: May 9, 2018
    Publication date: August 13, 2020
    Inventors: Min TENG, Baskar NAMMALWAR, Konstantin TAGANOV, Xiaoming LI, David T. PUERTA
  • Pyrone based compounds for treating bacterial infections
    Patent number: 10611747
    Abstract: The present teachings relate to pyrone derivatives, pharmaceutical compositions thereof, and methods of using such compounds to treat bacterial infections.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: April 7, 2020
    Assignee: FORGE THERAPEUTICS, INC.
    Inventors: Min Teng, Baskar Nammalwar, Konstantin Taganov, David T. Puerta
  • ANTIBACTERIAL COMPOUNDS
    Publication number: 20200095236
    Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Application
    Filed: May 9, 2018
    Publication date: March 26, 2020
    Inventors: Min TENG, Baskar NAMMALWAR, Konstantin TAGANOV, Xiaoming LI, David T. PUERTA, Serge CONVERS-REIGNIER, Holly ATTON, Ian YULE, Heather TYE, Adele FAULKNER, Alastair PARKES
  • HYDROXYPYRIMIDINONE AND HYDROXYPYRIMIDINONE BASED COMPOUNDS FOR TREATING BACTERIAL INFECTIONS
    Publication number: 20200010427
    Abstract: The present teachings relate to hydroxypyridinone and hydroxypyrimidinone derivatives, pharmaceutical compositions thereof, and methods of using such compounds to treat bacterial infections.
    Type: Application
    Filed: July 15, 2019
    Publication date: January 9, 2020
    Inventors: Min TENG, Baskar NAMMALWAR, Konstantin TAGANOV, David T. PUERTA
  • Substituted hydroxypyrimidinones for treating bacterial infections
    Patent number: 10414735
    Abstract: The present teachings relate to hydroxypyrimidinone derivatives of Formula IV, pharmaceutical compositions thereof, and methods of using such compounds to treat bacterial infections.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: September 17, 2019
    Assignee: FORGE THERAPEUTICS, INC.
    Inventors: Min Teng, Baskar Nammalwar, Konstantin Taganov, David T. Puerta