Patents by Inventor David T. Weaver

David T. Weaver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for humanizing antibodies and humanized antibodies made thereby
    Patent number: 8343489
    Abstract: Disclosed herein is the use of three-dimensional structure information to guide the process of modifying antibodies with amino acids from one or more templates or surrogates such that the antigen binding properties of the parent antibody are maintained and the immunogenicity potential is reduced when administered as a therapeutic in humans.
    Type: Grant
    Filed: March 21, 2007
    Date of Patent: January 1, 2013
    Inventors: David T. Weaver, Michael Rynkiewicz
  • Biomarkers For The Identification, Monitoring, And Treatment Of Non-Small Cell Lung Cancer (NSCLC)
    Publication number: 20110217713
    Abstract: This present invention compositions and methods of treating, diagnosing, prognosing cancer and methods of accessing/monitoring the responsiveness of a cancer cell to a therapeutic compound.
    Type: Application
    Filed: March 7, 2011
    Publication date: September 8, 2011
    Applicant: On-Q-ity
    Inventors: David T. Weaver, William E. Pierceall, Brian Ward
  • METHODS FOR HUMANIZING ANTIBODIES AND HUMANIZED ANTIBODIES MADE THEREBY
    Publication number: 20090130102
    Abstract: Disclosed herein is the use of three-dimensional structure information to guide the process of modifying antibodies with amino acids from one or more templates or surrogates such that the antigen binding properties of the parent antibody are maintained and the immunogenicity potential is reduced when administered as a therapeutic in humans.
    Type: Application
    Filed: March 21, 2007
    Publication date: May 21, 2009
    Inventors: David T. Weaver, Michael Rynkiewicz
  • Compositions and methods of treating cancer
    Publication number: 20090062196
    Abstract: This present invention compositions and methods of treating cancer and methods of accessing/monitoring the responsiveness of a cancer cell to a therapeutic compound.
    Type: Application
    Filed: October 22, 2007
    Publication date: March 5, 2009
    Inventors: Alan D'Andrea, David T. Weaver, Markus Grompe
  • Compounds and methods for treatment of thrombosis
    Patent number: 7217794
    Abstract: The present invention provides compounds that inhibit Factor XIa and methods of preventing or treating undesired thrombosis by administering a compound of the invention to a mammal. The invention also provides three-dimensional structures of Factor XIa and methods for designing or selecting additional Factor XIa inhibitors using these structures.
    Type: Grant
    Filed: April 2, 2004
    Date of Patent: May 15, 2007
    Assignee: Daiamed, Inc.
    Inventors: Sherin S. Abdel-Meguid, Robert E. Babine, Hongfeng Deng, Lei Jin, Jian Lin, Scott R. Magee, Harold V. Meyers, Pramod Pandey, Michael J. Rynkiewicz, David T. Weaver, Zihong Gho, Thomas D. Bannister