Patents by Inventor David Temelkoff

David Temelkoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS USEFUL IN HIV THERAPY
    Publication number: 20240182473
    Abstract: The invention relates to compounds of Formula (I), (Ia), (II) or (IIa), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
    Type: Application
    Filed: November 14, 2023
    Publication date: June 6, 2024
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED, VIIV HEALTHCARE COMPANY
    Inventors: Martha Alicia DE LA ROSA, John F. MILLER, B. Narasimhulu NAIDU, Vicente SAMANO, David TEMELKOFF, Emile Johann VELTHUISEN
  • COMPOUNDS USEFUL IN HIV THERAPY
    Publication number: 20220411425
    Abstract: The invention relates to a compound having the structure: or a pharmaceutically acceptable salt thereof, along with pharmaceutical compositions and therapeutic methods thereof.
    Type: Application
    Filed: June 1, 2021
    Publication date: December 29, 2022
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED, VIIV HEALTHCARE COMPANY
    Inventors: Martha Alicia DE LA ROSA, John F. MILLER, B. Narasimhulu NAIDU, Vicente SAMANO, David TEMELKOFF, Emile Johann VELTHUISEN
  • COMPOUNDS USEFUL IN HIV THERAPY
    Publication number: 20220298160
    Abstract: The invention relates to compounds of Formulae (I)-(II), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
    Type: Application
    Filed: August 28, 2020
    Publication date: September 22, 2022
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED, VIIV HEALTHCARE COMPANY
    Inventors: Martha Alicia DE LA ROSA, John MILLER, Lita S. SUWANDI, David TEMELKOFF, Emile Johann VELTHUISEN
  • 4'-ETHYNYL-2'-DEOXYADENOSINE DERIVATIVES AND THEIR USE IN HIV THERAPY
    Publication number: 20220259252
    Abstract: The invention relates to compounds of Formulae (I) and (II), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
    Type: Application
    Filed: July 30, 2020
    Publication date: August 18, 2022
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED, VIIV HEALTHCARE COMPANY
    Inventors: John MILLER, Vicente SAMANO, David TEMELKOFF, Emile Johann VELTHUISEN
  • Compounds Useful in HIV Therapy
    Publication number: 20220117993
    Abstract: The invention relates to compounds of the Formula: salts thereof, pharmaceutical compositions thereof, combinations thereof, as well as therapeutic methods of treatment and prevention.
    Type: Application
    Filed: August 8, 2019
    Publication date: April 21, 2022
    Applicants: GlaxoSmithKline Intellectual Property (No. 2) Limited, VIIV Healthcare Company
    Inventors: John Franklin MILLER, David TEMELKOFF, Emile Johann VELTHUISEN, Martha Alicia DE LA ROSA, Lita SUWANDI, B. Narasimhulu NAIDU
  • Compounds Useful in HIV Therapy
    Publication number: 20210323993
    Abstract: The invention relates to compounds of Formulae (I), (Ia), (II) and (IIa), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
    Type: Application
    Filed: August 28, 2019
    Publication date: October 21, 2021
    Applicants: GlaxosmithKline Intellectual Property (No. 2) Limited, ViiV Healthcare Company
    Inventors: John MILLER, David TEMELKOFF, Emile Johann VELTHUISEN, Martha Alicia DE LA ROSA, Lisa SUWANDI
  • MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE
    Publication number: 20210078988
    Abstract: Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases.
    Type: Application
    Filed: June 27, 2018
    Publication date: March 18, 2021
    Inventors: Ghotas EVINDAR, Wieslaw Mieczyslaw KAZMIERSKI, John Franklin MILLER, Vicente SAMANO, Lita SUWANDI, David TEMELKOFF, Yoshiaki WASHIO, Bing XIA
  • Medical Use
    Publication number: 20200407393
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Application
    Filed: March 6, 2019
    Publication date: December 31, 2020
    Applicants: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED, VIIV HEALTHCARE COMPANY
    Inventors: Martha Alicia DE LA ROSA, John Franklin MILLER, David TEMELKOFF, Emile Johann VELTHUISEN
  • ANTIBODY-DRUG CONJUGATES AND THERAPEUTIC METHODS USING THE SAME
    Publication number: 20190328900
    Abstract: The invention discloses an antibody-drug conjugate of Formula (I): Ab-[L-Dn]x??(I) wherein: Ab comprises a broadly neutralizing anti-HIV antibody; L comprises a linker molecule covalently bonded to said broadly neutralizing anti-HIV antibody; D comprises one or more drugs comprising an HIV therapeutic compound covalently bonded to said linker molecule L, wherein said one or more broadly neutralizing anti-HIV antibodies Ab specifically bind to an HIV envelope glycoprotein and said one or more drugs D specifically bind to an HIV envelope glycoprotein; n is selected from 1-4; and x is selected from 1-12.
    Type: Application
    Filed: June 30, 2017
    Publication date: October 31, 2019
    Inventors: Jerry JEFFREY, Jun TANG, Vincent Wing-Fai TAI, David TEMELKOFF, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • Isoindoline derivatives for use in the treatment of a viral infection
    Patent number: 10112899
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: October 30, 2018
    Assignee: ViiV HEALTHCARE UK LIMITED
    Inventors: Brian Alvin Johns, Emile Johann Velthuisen, Jason Gordon Weatherhead, Lita Suwandi, David Temelkoff
  • ISOINDOLINE DERIVATIVES FOR USE IN THE TREATMENT OF A VIRAL INFECTION
    Publication number: 20180244617
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: July 6, 2015
    Publication date: August 30, 2018
    Inventors: Brian Alvin JOHNS, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD, Lita SUWANDI, David TEMELKOFF
  • Compounds and methods for treating HIV
    Patent number: 9163023
    Abstract: Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the retrovirus family of viruses such as the Human Immunodeficiency Virus (HIV).
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: October 20, 2015
    Assignee: ViiV Healthcare UK Limited
    Inventors: Martha Alicia De La Rosa, Brian Alvin Johns, Wieslaw Mieczyslaw Kazmierski, Vicente Samano, Lita Suwandi, David Temelkoff, Emile Velthuisen, Jason Gordon Weatherhead
  • COMPOUNDS AND METHODS FOR TREATING HIV
    Publication number: 20150191469
    Abstract: Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the retrovirus family of viruses such as the Human Immunodeficiency Virus (HIV).
    Type: Application
    Filed: July 10, 2013
    Publication date: July 9, 2015
    Inventors: Martha Alicia De La Rosa, Brian Alvin Johns, Wieslaw Mieczyslaw Kazmierski, Vicente Samano, Lita Suwandi, David Temelkoff, Emile Velthuisen, Jason Gordon Weatherhead